Mechanisms of cellular communication through intercellular protein transfer

•  Introduction •  Intercellular membrane transfer a widespread phenomenon ‐  Intercellular protein transfers between the cells of immune system ‐  Intercellular protein transfer between the cells related – unrelated to immunity ‐  Intercellular protein transfer in the systems unrelated to immunity •  The pathways responsible for the intercellular membrane transfer [ 18] ‐  TCR‐mediated internalization and recycling ‐  Dissociation‐associated pathway ‐  Exosome uptake ‐  Membrane nanotube formation •  Functional relevance to immune responses ‐  Stimulatory effect on immune responses ‐  Suppressive effect on immune responses ‐  Unusual phenotypes and negative consequences ‐  Technological consequences •  Perspectives