DNA methylation and immunohistochemical analysis of the S100A4 calcium binding protein in human prostate cancer

The role of DNA methylation in the transcriptional regulation of S100A4 is unknown in human prostate cancer.

[1]  Rajvir Dahiya,et al.  Epigenetic changes in prostate cancer: implication for diagnosis and treatment. , 2005, Journal of the National Cancer Institute.

[2]  T. Tkatch,et al.  Transcriptional regulation of the mts1 gene in human lymphoma cells: the role of DNA-methylation. , 1995, Biochimica et biophysica acta.

[3]  L. Mazzucchelli Protein S100A4: too long overlooked by pathologists? , 2002, The American journal of pathology.

[4]  J. Rees,et al.  Genetic change in actinic keratoses. , 1996, Oncogene.

[5]  O. Witte,et al.  S100A5: a marker of recurrence in WHO grade I meningiomas , 2004, Neuropathology and applied neurobiology.

[6]  P. Rudland,et al.  Induction of the metastatic phenotype by transfection of a benign rat mammary epithelial cell line with the gene for p9Ka, a rat calcium-binding protein, but not with the oncogene EJ-ras-1. , 1993, Oncogene.

[7]  S. Cross,et al.  Promoter hyper‐methylation of calcium binding proteins S100A6 and S100A2 in human prostate cancer , 2005, The Prostate.

[8]  D. Neal,et al.  Expression of S100A4 protein is associated with metastasis and reduced survival in human bladder cancer , 2002, The Journal of pathology.

[9]  P. Rudland,et al.  S100A4 regulates cell motility and invasion in an in vitro model for breast cancer metastasis , 2004, British Journal of Cancer.

[10]  Tajamul Hussain,et al.  Differential expression of S100A2 and S100A4 during progression of human prostate adenocarcinoma. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[11]  F. Rehman,et al.  Fenretinide stimulates redox-sensitive ceramide production in breast cancer cells: potential role in drug-induced cytotoxicity , 2004, British Journal of Cancer.

[12]  C. Heizmann,et al.  Inverse expression of S100A4 and E-cadherin is associated with metastatic potential in gastric cancer. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

[13]  T. Fujiyoshi,et al.  Cloning of the sequences expressed abundantly in established cell lines: identification of a cDNA clone highly homologous to S-100, a calcium binding protein. , 1988, Journal of biochemistry.

[14]  S. Cross,et al.  Dysregulated expression of S100A11 (calgizzarin) in prostate cancer and precursor lesions. , 2004, Human pathology.

[15]  C. Heizmann,et al.  The S100 family of EF-hand calcium-binding proteins: functions and pathology. , 1996, Trends in biochemical sciences.

[16]  J. Winstanley,et al.  Prognostic significance of the metastasis-inducing protein S100A4 (p9Ka) in human breast cancer. , 2000, Cancer research.

[17]  C. Heizmann,et al.  S100 proteins: structure, functions and pathology. , 2002, Frontiers in bioscience : a journal and virtual library.

[18]  J. Issa CpG island methylator phenotype in cancer , 2004, Nature Reviews Cancer.

[19]  S. Cross,et al.  S100A6 (Calcyclin) is a prostate basal cell marker absent in prostate cancer and its precursors , 2004, British Journal of Cancer.

[20]  S. Cross,et al.  Expression of S100 proteins in normal human tissues and common cancers using tissue microarrays: S100A6, S100A8, S100A9 and S100A11 are all overexpressed in common cancers , 2005, Histopathology.

[21]  Yohko Nakamura,et al.  Expression of antisense RNA to S100A4 gene encoding an S100-related calcium-binding protein suppresses metastatic potential of high-metastatic Lewis lung carcinoma cells , 1997, Oncogene.

[22]  H. Kreipe,et al.  Prognostic significance of calcium-binding protein S100A4 in colorectal cancer. , 2002, Gastroenterology.

[23]  D. Helfman,et al.  The metastasis associated protein S100A4: role in tumour progression and metastasis , 2005, British Journal of Cancer.

[24]  M. Grigorian,et al.  Suppression of tumor development and metastasis formation in mice lacking the S100A4(mts1) gene. , 2005, Cancer research.

[25]  C. Iacobuzio-Donahue,et al.  Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma. , 2003, Cancer research.

[26]  B. B. Mukherjee,et al.  Transformation of normal rat kidney cells by v-K-ras enhances expression of transin 2 and an S-100-related calcium-binding protein. , 1992, Oncogene.

[27]  P. Rudland,et al.  Differential Reactivity of the RatS100A4(p9Ka) Gene to Sodium Bisulfite Is Associated with Differential Levels of the S100A4 (p9Ka) mRNA in Rat Mammary Epithelial Cells* , 1999, The Journal of Biological Chemistry.

[28]  R. Donato,et al.  Intracellular and extracellular roles of S100 proteins , 2003, Microscopy research and technique.

[29]  Naoko Nakamura,et al.  Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines , 1998, Clinical & Experimental Metastasis.

[30]  J. Cameron,et al.  Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation. , 2002, The American journal of pathology.