Screening for mutations in synaptotagmin XI in Parkinson's disease.

[1]  Daniel R. Scoles,et al.  The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI. , 2003, Human molecular genetics.

[2]  E. Hirsch,et al.  The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration. , 2003, Human molecular genetics.

[3]  N. Thakor,et al.  Parkin Facilitates the Elimination of Expanded Polyglutamine Proteins and Leads to Preservation of Proteasome Function* , 2003, Journal of Biological Chemistry.

[4]  D. Hernandez,et al.  Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease. , 2003, Human molecular genetics.

[5]  Jian Feng,et al.  Parkin Binds to α/β Tubulin and Increases their Ubiquitination and Degradation , 2003, The Journal of Neuroscience.

[6]  A. Abeliovich,et al.  Parkin Is a Component of an SCF-like Ubiquitin Ligase Complex and Protects Postmitotic Neurons from Kainate Excitotoxicity , 2003, Neuron.

[7]  Richard Paylor,et al.  Synaptic Vesicle Depletion Correlates with Attenuated Synaptic Responses to Prolonged Repetitive Stimulation in Mice Lacking α-Synuclein , 2002, The Journal of Neuroscience.

[8]  T. Sherer,et al.  Mechanistic Approaches to Parkinson's Disease Pathogenesis , 2002, Brain pathology.

[9]  T. Hashikawa,et al.  CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. , 2002, Molecular cell.

[10]  B. Hyman,et al.  Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. , 2002, The American journal of pathology.

[11]  J. Schulz,et al.  Parkinson's disease: one biochemical pathway to fit all genes? , 2002, Trends in molecular medicine.

[12]  F. Moreau,et al.  Parkin and CASK/LIN-2 Associate via a PDZ-mediated Interaction and Are Co-localized in Lipid Rafts and Postsynaptic Densities in Brain* , 2002, The Journal of Biological Chemistry.

[13]  M. Jackson,et al.  Synaptotagmin Modulation of Fusion Pore Kinetics in Regulated Exocytosis of Dense-Core Vesicles , 2001, Science.

[14]  C. Ross,et al.  Parkin ubiquitinates the α-synuclein–interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease , 2001, Nature Medicine.

[15]  S. Minoshima,et al.  Parkin is associated with cellular vesicles , 2001, Journal of neurochemistry.

[16]  N. Hattori,et al.  An Unfolded Putative Transmembrane Polypeptide, which Can Lead to Endoplasmic Reticulum Stress, Is a Substrate of Parkin , 2001, Cell.

[17]  Nobutaka Hattori,et al.  Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease , 2001, Science.

[18]  D. Atlas.  Functional and physical coupling of voltage‐sensitive calcium channels with exocytotic proteins: ramifications for the secretion mechanism , 2001, Journal of neurochemistry.

[19]  T. Dawson,et al.  Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[20]  Shinsei Minoshima,et al.  Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase , 2000, Nature Genetics.

[21]  S. Minoshima,et al.  Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism , 1998, Nature.

[22]  T. Südhof,et al.  The Evolutionary Pressure to Inactivate , 1997, The Journal of Biological Chemistry.

[23]  Thomas C. Südhof,et al.  Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins , 1995, Nature.

[24]  S. Sprang,et al.  Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold , 1995, Cell.

[25]  Richard G. W. Anderson,et al.  Functional properties of multiple synaptotagmins in brain , 1994, Neuron.

[26]  K. Mikoshiba,et al.  Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II. , 1994, The Journal of biological chemistry.

[27]  Richard G. W. Anderson,et al.  Synaptotagmin I is a high affinity receptor for clathrin AP-2: Implications for membrane recycling , 1994, Cell.

[28]  T. Südhof,et al.  A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding. , 1993, The Journal of biological chemistry.

[29]  P. Oefner,et al.  High-resolution liquid chromatography of DNA fragments on non-porous poly(styrene-divinylbenzene) particles. , 1993, Nucleic acids research.

[30]  C. Ross,et al.  Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein. , 2003, Human molecular genetics.

[31]  S Rozen,et al.  Primer3 on the WWW for general users and for biologist programmers. , 2000, Methods in molecular biology.

[32]  D. Gjerde,et al.  Detection of single-nucleotide polymorphisms with the WAVE DNA fragment analysis system. , 1997, Genetic testing.