MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

[1]  J. Bonifacino,et al.  Association with BiP and aggregation of class II MHC molecules synthesized in the absence of invariant chain. , 1994, The EMBO journal.

[2]  A. Goldberg,et al.  Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. , 1993, Nature.

[3]  D. Finley,et al.  MHC-linked LMP gene products specifically alter peptidase activities of the proteasome , 1993, Nature.

[4]  S. Tonegawa,et al.  TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective , 1993, Cell.

[5]  J. Neefjes,et al.  Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter. , 1993, Science.

[6]  F. Sinigaglia,et al.  Promiscuous and allele-specific anchors in HLA-DR-binding peptides , 1993, Cell.

[7]  D. Wiley,et al.  Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 , 1993, Nature.

[8]  R. Germain,et al.  Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules , 1993, Nature.

[9]  K. Rock,et al.  Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[10]  R. Germain,et al.  Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression , 1993, The Journal of experimental medicine.

[11]  R. Germain,et al.  Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling , 1993, The Journal of experimental medicine.

[12]  J. Yewdell,et al.  Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments , 1993, The Journal of experimental medicine.

[13]  C. Benoist,et al.  Mice lacking the MHC class II-associated invariant chain , 1993, Cell.

[14]  J. Pfeifer,et al.  Phagocytic processing of bacterial antigens for class I MHC presentation to T cells , 1993, Nature.

[15]  R. Germain,et al.  The biochemistry and cell biology of antigen processing and presentation. , 1993, Annual review of immunology.

[16]  A. Miller,et al.  Dominance and crypticity of T cell antigenic determinants. , 1993, Annual review of immunology.

[17]  P. Cresswell,et al.  HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides , 1992, Nature.

[18]  William S. Lane,et al.  Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle , 1992, Nature.

[19]  P. Cresswell,et al.  Proteasome subunits encoded in the MHC are not generally required for the processing of peptides bound by MHC class I molecules , 1992, Nature.

[20]  J. Neefjes,et al.  Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation , 1992, Nature.

[21]  H. Geuze,et al.  Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells , 1992, The Journal of cell biology.

[22]  Dean R. Madden,et al.  The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC , 1992, Cell.

[23]  W. T. Schaiff,et al.  HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cells , 1992, The Journal of experimental medicine.

[24]  William S. Lane,et al.  Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size , 1992, Nature.

[25]  P. A. Peterson,et al.  Emerging principles for the recognition of peptide antigens by MHC class I molecules. , 1992, Science.

[26]  E. Bikoff Formation of complexes between self-peptides and MHC class II molecules in cells defective for presentation of exogenous protein antigens. , 1992, Journal of immunology.

[27]  A Sette,et al.  Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad. , 1992, Science.

[28]  Eric O Long,et al.  Processing pathways for presentation of cytosolic antigen to MHC class II-restricted T cells , 1992, Nature.

[29]  A. Goldberg,et al.  Proteolysis, proteasomes and antigen presentation , 1992, Nature.

[30]  E. Degen,et al.  Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2- microglobulin and peptide , 1992, The Journal of experimental medicine.

[31]  J. Slot,et al.  Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi , 1992, Nature.

[32]  N. Huskisson,et al.  Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule , 1992, Nature.

[33]  F. Maxfield,et al.  Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes , 1992, The Journal of cell biology.

[34]  M. Anderson,et al.  Invariant chain can function as a chaperone protein for class II major histocompatibility complex molecules. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[35]  R. Henderson,et al.  Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. , 1992, Science.

[36]  H. Grey,et al.  Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor , 1992, Cell.

[37]  J. Monaco Genes in the MHC that may affect antigen processing , 1992, Current Biology.

[38]  A. Rudensky,et al.  Sequence analysis of peptides bound to MHC class II molecules , 1991, Nature.

[39]  A. Lanzavecchia,et al.  Processed antigen binds to newly synthesized mhc class II molecules in antigen-specific B lymphocytes , 1991, Cell.

[40]  R. Germain,et al.  MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding , 1991, Nature.

[41]  P. Allen,et al.  Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. , 1991, Science.

[42]  H. Rammensee,et al.  Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules , 1991, Nature.

[43]  D. Wiley,et al.  Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution. , 1991, Journal of molecular biology.

[44]  W R Taylor,et al.  A hypothetical model for the peptide binding domain of hsp70 based on the peptide binding domain of HLA. , 1991, The EMBO journal.

[45]  R. Germain,et al.  Invariant chain promotes egress of poorly expressed, haplotype-mismatched class II major histocompatibility complex A alpha A beta dimers from the endoplasmic reticulum/cis-Golgi compartment. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[46]  S. Weiss,et al.  MHC class II—Restricted presentation of intracellular antigen , 1991, Cell.

[47]  H. Geuze,et al.  Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments , 1991, Nature.

[48]  F. Brodsky,et al.  The cell biology of antigen processing and presentation. , 1991, Annual review of immunology.

[49]  R. Steinman,et al.  The dendritic cell system and its role in immunogenicity. , 1991, Annual review of immunology.

[50]  T. Olson,et al.  Targeting specific proteins for lysosomal proteolysis. , 1991, Biomedica biochimica acta.

[51]  P. A. Peterson,et al.  Intracellular transport of class II MHC molecules directed by invariant chain , 1990, Nature.

[52]  P. A. Peterson,et al.  Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways , 1990, Nature.

[53]  P. Cresswell,et al.  Intracellular transport and peptide binding properties of HLA class II glycoproteins. , 1990, Seminars in immunology.

[54]  P. Cresswell,et al.  Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding , 1990, Nature.

[55]  M. Cohn,et al.  The Protection: The Unit of Humoral Immunity Selected by Evolution , 1990, Immunological Reviews.

[56]  P. Jensen,et al.  Regulation of antigen presentation by acidic pH , 1990, The Journal of experimental medicine.

[57]  Joseph Schlessinger,et al.  Signal transduction by receptors with tyrosine kinase activity , 1990, Cell.

[58]  M. Bevan,et al.  Class I-restricted processing and presentation of exogenous cell- associated antigen in vivo , 1990, The Journal of experimental medicine.

[59]  M. A. Saper,et al.  Specificity pockets for the side chains of peptide antigens in HLA-Aw68 , 1990, Nature.

[60]  L Adorini,et al.  Capacity of intact proteins to bind to MHC class II molecules. , 1989, Journal of immunology.

[61]  H. Ljunggren,et al.  Association of class I major histocompatibility heavy and light chains induced by viral peptides , 1989, Nature.

[62]  R. Schwartz Acquisition of immunologic self-tolerance , 1989, Cell.

[63]  C. Janeway,et al.  Cross-linking and conformational change in T-cell receptors: role in activation and in repertoire selection. , 1989, Cold Spring Harbor symposia on quantitative biology.

[64]  M. Bevan,et al.  Introduction of soluble protein into the class I pathway of antigen processing and presentation , 1988, Cell.

[65]  P. Cresswell,et al.  Role for intracellular proteases in the processing and transport of class II HLA antigens. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[66]  F Celada,et al.  Differential activation of T cell clones stimulated by macrophages exposed to antigen complexed with monoclonal antibodies. A possible influence of paratope specificity on the mode of antigen processing. , 1988, Journal of immunology.

[67]  J. Yewdell,et al.  Cells process exogenous proteins for recognition by cytotoxic T lymphocytes. , 1988, Science.

[68]  M. A. Saper,et al.  Structure of the human class I histocompatibility antigen, HLA-A2 , 1987, Nature.

[69]  J. Berzofsky,et al.  Antibody conjugates mimic specific B cell presentation of antigen: relationship between T and B cell specificity. , 1987, Journal of immunology.

[70]  M. Bevan Class discrimination in the world of immunology , 1987, Nature.

[71]  R. Germain Immunology: The ins and outs of antigen processing and presentations , 1986, Nature.

[72]  T. Braciale,et al.  Differences in antigen presentation to MHC class I-and class II- restricted influenza virus-specific cytolytic T lymphocyte clones , 1986, The Journal of experimental medicine.

[73]  P. Cresswell Intracellular class II HLA antigens are accessible to transferrin-neuraminidase conjugates internalized by receptor-mediated endocytosis. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[74]  K. Rock,et al.  Antigen presentation by hapten-specific B lymphocytes. II. Specificity and properties of antigen-presenting B lymphocytes, and function of immunoglobulin receptors. , 1985, Journal of immunology.

[75]  J. Davey,et al.  Cytotoxic T cells recognize fragments of the influenza nucleoprotein , 1985, Cell.

[76]  Antonio Lanzavecchia,et al.  Antigen-specific interaction between T and B cells , 1985, Nature.

[77]  R. Schwartz T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex. , 1985, Annual review of immunology.

[78]  H. Mcdevitt,et al.  Histocompatibility-linked immune response genes. , 1972, Science.

[79]  N. Klinman THE MECHANISM OF ANTIGENIC STIMULATION OF PRIMARY AND SECONDARY CLONAL PRECURSOR CELLS , 1972, The Journal of experimental medicine.

[80]  R. Barth,et al.  Strong and Weak Histocompatibility Gene Differences in Mice and Their Role in the Rejection of Homografts of Tumors and Skin , 1956, Annals of surgery.