Induced changes of cerebrospinal fluid volume. Effects during continuous monitoring of ventricular fluid pressure.

Observations were made to test the hypothesis that the relationship between additions to the volume of the intracranial contents and the resulting intracranial pressure is exponential, and that during the development of intracranial space-cocupying lesions there is a stage before the resting level of intracranial pressure is much increased when a small additional volume will result in a considerable rise in pressure. The effect on ventricular fluid pressure (VFP) of an induced change of 1 ml in cerebrospinal fluid volume was studied in 20 patients during continuous monitoring of VFP. The effect of surgical removal of intracranial space-occupying lesions on this relationship was studied in an additional three patients. The results support the hypothesis, and in individual patients this technique provides useful data about the remaining compensatory capacity for further increases in intracranial volume.

[1]  D. Mcdowall,et al.  Cerebrospinal fluid pressure measurements during anæsthesia , 1966 .

[2]  B. Jennett,et al.  Intracranial-pressure changes following head injury. , 1970, Lancet.

[3]  J. R. Nelson,et al.  An evaluation of the cerebrospinal fluid infusion test for hydrocephalus , 1971, Neurology.

[4]  J. Miller,et al.  Intracranial Volume/Pressure Relationships during Continuous Monitoring of Ventricular Fluid Pressure , 1972 .

[5]  T. Langfitt,et al.  Cerebral vasomotor paralysis produced by intracranial hypertension , 1965, Neurology.

[6]  R. Katzman.,et al.  A simple constant‐infusion manometric test for measurement of CSF absorption , 1970, Neurology.

[7]  N. Kassell,et al.  TRANSMISSION OF INCREASED INTRACRANIAL PRESSURE. I. WITHIN THE CRANIOSPINAL AXIS. , 1964, Journal of neurosurgery.

[8]  N. Lundberg,et al.  Continuous recording and control of ventricular fluid pressure in neurosurgical practice. , 1962, Acta psychiatrica Scandinavica. Supplementum.

[9]  N. Battistini,et al.  Derangement of regional cerebral blood flow and of its regulatory mechanisms in acute cerebrovascular lesions , 1968, Neurology.

[10]  B. Jennett,et al.  The Uses of Intracranial Pressure Monitoring in Clinical Management , 1972 .

[11]  F. Foldes,et al.  CHANGES IN CEREBROSPINAL FLUID PRESSURE UNDER THE INFLUENCE OF CONTINUOUS SUBARACHNOIDAL INFUSION OF NORMAL SALINE. , 1948, The Journal of clinical investigation.

[12]  S. Cronqvist,et al.  Clinical investigations on interrelations between intracranial pressure and intracranial hemodynamics. , 1968, Progress in brain research.

[13]  B. Podolsky,et al.  The mechanism of the change in cerebrospinal fluid pressure following an induced change in the volume of the fluid space. , 1953, The Journal of laboratory and clinical medicine.

[14]  L. J. Pollock,et al.  CEREBROSPINAL FLUID PRESSURE , 1936 .