Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions.
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P. Libby | G. Sukhova | U. Schönbeck | S. Coulter | P. Graber | S. Coulter
[1] M A Konerding,et al. Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. , 1999, Circulation.
[2] Lipsky Pe. Role of cyclooxygenase-1 and -2 in health and disease. , 1999 .
[3] J. Wallace,et al. Limited anti‐inflammatory efficacy of cyclo‐oxygenase‐2 inhibition in carrageenan‐airpouch inflammation , 1999, British journal of pharmacology.
[4] G. FitzGerald,et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[5] P. Lipsky. Role of cyclooxygenase-1 and -2 in health and disease. , 1999, American journal of orthopedics.
[6] P. Libby,et al. Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells. , 1998, Circulation research.
[7] C. Bruni,et al. Helicobacter pylori Up-regulates Cyclooxygenase-2 mRNA Expression and Prostaglandin E2 Synthesis in MKN 28 Gastric Mucosal Cells in Vitro * , 1998, The Journal of Biological Chemistry.
[8] J. Pepper,et al. Cyclo-oxygenase-2 regulates inducible ICAM-1 and VCAM-1 expression in human vascular smooth muscle cells. , 1998, Biochemical and biophysical research communications.
[9] R. DuBois,et al. Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells , 1998, Cell.
[10] P. Libby,et al. Reduction of atherosclerosis in mice by inhibition of CD40 signalling , 1998, Nature.
[11] P. Libby,et al. Macrophages in Human Atheroma Contain PPARγ: Differentiation-Dependent Peroxisomal Proliferator-Activated Receptor γ (PPARγ) Expression and Reduction of MMP-9 Activity through PPARγ Activation in Mononuclear Phagocytes in Vitro , 1998 .
[12] E. Uhl,et al. Expression of mRNA for Phospholipase A2, Cyclooxygenases, and Lipoxygenases in Cultured Human Umbilical Vascular Endothelial and Smooth Muscle Cells and in Biopsies from Umbilical Arteries and Veins , 1998, Journal of Vascular Research.
[13] A. Quyyumi,et al. Aspirin improves endothelial dysfunction in atherosclerosis. , 1998, Circulation.
[14] Terry J. Smith,et al. Cutting Edge: CD40 Engagement Up-Regulates Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Human Lung Fibroblasts , 1998, The Journal of Immunology.
[15] B. Graf,et al. CD40 engagement up-regulates cyclooxygenase-2 expression and prostaglandin E2 production in human lung fibroblasts. , 1998, Journal of immunology.
[16] J. Vane,et al. Cyclooxygenases 1 and 2. , 1998, Annual review of pharmacology and toxicology.
[17] P. Libby,et al. Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture? , 1997, Circulation research.
[18] J. Pepper,et al. Induction of cyclooxygenase-2 in human saphenous vein and internal mammary artery. , 1997, Arteriosclerosis, thrombosis, and vascular biology.
[19] P. Libby,et al. Ligation of CD40 Activates Interleukin 1β-converting Enzyme (Caspase-1) Activity in Vascular Smooth Muscle and Endothelial Cells and Promotes Elaboration of Active Interleukin 1β* , 1997, The Journal of Biological Chemistry.
[20] P. Libby,et al. Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor. , 1997, Circulation.
[21] R. Thompson,et al. Prostaglandin E2 synthesis and cyclooxygenase expression in abdominal aortic aneurysms. , 1997, Journal of vascular surgery.
[22] P. Libby,et al. Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[23] R. Kurumbail,et al. Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents , 1997, Nature.
[24] R. DuBois,et al. Prostaglandin endoperoxide synthase: why two isoforms? , 1996, The American journal of physiology.
[25] H. Jacobson,et al. Functional and molecular aspects of renal prostaglandin receptors. , 1996, Journal of the American Society of Nephrology : JASN.
[26] R. Evans,et al. The RXR heterodimers and orphan receptors , 1995, Cell.
[27] B. Spiegelman,et al. 15-Deoxy-Δ 12,14-Prostaglandin J 2 is a ligand for the adipocyte determination factor PPARγ , 1995, Cell.
[28] J. Lehmann,et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation , 1995, Cell.
[29] R. DuBois,et al. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2 , 1995, Cell.
[30] D. Reed,et al. Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[31] J. Otto,et al. Different Intracellular Locations for Prostaglandin Endoperoxide H Synthase-1 and −2 (*) , 1995, The Journal of Biological Chemistry.
[32] A. Durandy,et al. Recombinant Soluble Trimeric CD40 Ligand Is Biologically Active * , 1995, The Journal of Biological Chemistry.
[33] K. Chadee,et al. Proinflammatory cytokines regulate cyclooxygenase-2 mRNA expression in human macrophages. , 1995, Biochemical and biophysical research communications.
[34] P. Libby,et al. Cytokines Regulate Genes Involved in Atherogenesis a , 1994, Annals of the New York Academy of Sciences.
[35] B. Spiegelman,et al. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. , 1995, Cell.
[36] P. Libby,et al. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. , 1994, The Journal of clinical investigation.
[37] J. Maclouf,et al. Regulation of cyclooxygenase-2 expression in aortic smooth muscle cells. , 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.
[38] C. Ji,et al. Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin. , 1994, The Journal of biological chemistry.
[39] A. Ristimäki,et al. Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation. , 1994, The Journal of biological chemistry.
[40] K. Seibert,et al. Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[41] J. Mancini,et al. Mutation of serine‐516 in human prostaglandin G/H synthase‐2 to methionine or aspirin acetylation of this residue stimulates 15‐R‐HETE synthesis , 1994, FEBS letters.
[42] P. Loll,et al. The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1 , 1994, Nature.
[43] C. Thiemermann,et al. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[44] A. Ford-hutchinson,et al. Expression of mRNA for cyclooxygenase‐1 and cyclooxygenase‐2 in human tissues , 1993, FEBS letters.
[45] M. Kowala,et al. Prostacyclin agonists reduce early atherosclerosis in hyperlipidemic hamsters. Octimibate and BMY 42393 suppress monocyte chemotaxis, macrophage cholesteryl ester accumulation, scavenger receptor activity, and tumor necrosis factor production. , 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.
[46] T. Hla,et al. Human cyclooxygenase-2 cDNA. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[47] D. Hajjar,et al. Signal transduction in atherosclerosis: integration of cytokines and the eicosanoid network , 1992, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[48] W. Stetler-Stevenson,et al. Interleukin 4 inhibition of prostaglandin E2 synthesis blocks interstitial collagenase and 92-kDa type IV collagenase/gelatinase production by human monocytes. , 1992, The Journal of biological chemistry.
[49] K. Seibert,et al. The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. , 1990, The Journal of biological chemistry.
[50] A. Marcus,et al. Platelet-neutrophil-smooth muscle cell interactions: lipoxygenase-derived mono- and dihydroxy acids activate cholesteryl ester hydrolysis by the cyclic AMP dependent protein kinase cascade. , 1989, Biochemistry.
[51] D. Levy,et al. Identification of a phorbol ester-repressible v-src-inducible gene. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[52] J. Mehta,et al. Increased prostacyclin and thromboxane A2 biosynthesis in atherosclerosis. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[53] T. Tanabe,et al. Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence , 1988, FEBS letters.
[54] J. Vane,et al. Endothelium-derived relaxing factor reduces platelet adhesion to bovine endothelial cells. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[55] P. Needleman,et al. Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase). , 1988, The Journal of biological chemistry.
[56] D. Dewitt,et al. Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[57] M. Kerstein,et al. Prostacyclin, Thromboxane A2, and Prostaglandin E2 Formation in Atherosclerotic Human Carotid Artery , 1988, Arteriosclerosis.
[58] J. Rosenbloom,et al. PGE2 causes a coordinate decrease in the steady state levels of fibronectin and types I and III procollagen mRNAs in normal human dermal fibroblasts. , 1987, Biochemical and biophysical research communications.
[59] Arthur C. Guyton,et al. Handbook of Physiology—The Cardiovascular System , 1985 .
[60] A. K. Pedersen,et al. Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation. , 1984, The New England journal of medicine.
[61] B. Weksler,et al. Metabolic activity of cholesteryl esters in aortic smooth muscle cells is altered by prostaglandins I2 and E2. , 1983, Journal of lipid research.
[62] A. M. Lefer,et al. Dissociation of vasoconstrictor and platelet aggregatory activities of thromboxane by carbocyclic thromboxane A2, a stable analog of thromboxane A2. , 1980, Proceedings of the National Academy of Sciences of the United States of America.
[63] H. Sinzinger,et al. PROSTACYCLIN GENERATION IN ATHEROSCLEROTIC ARTERIES , 1979, The Lancet.
[64] S Moncada,et al. The role of prostacyclin in vascular tissue. , 1979, Federation proceedings.
[65] G. Milo,et al. Fatty acids and their prostaglandin derivatives: inhibitors of proliferation in aortic smooth muscle cells. , 1977, Science.
[66] V. Ziboh,et al. Inhibition of cholesterol esterification in rabbit aorta by prostaglandin E2. , 1977, Atherosclerosis.
[67] J. Vane,et al. An Enzyme Isolated from Arteries Transforms Prostaglandin Endoperoxides to an Unstable Substance that Inhibits Platelet Aggregation. , 1977 .
[68] J. Vane,et al. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation , 1976, Nature.
[69] S. Yamamoto,et al. Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. , 1976, The Journal of biological chemistry.
[70] A. Busuttil,et al. POLYPLOIDAL GIANT CELLS IN A LARYNGEAL BIOPSY , 1974 .
[71] J. Vane,et al. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. , 1971, Nature: New biology.