Enhancement of solubility of aceclofenac by using different solubilization technique

The objective of present research is to explore the application of different solubilization technique in the waterinsoluble drugs and to reduce concentration of hydrotropic agent produce its own toxicity. In case of synergistic effect in solubility due mixing of hydrotropic agent , say, the toxic level of individual can further be lowered because still less concentration of the hydrotropic agents shall be sufficient for a desired enhancement in solubility.