Leptin Inhibits Bone Formation through a Hypothalamic Relay A Central Control of Bone Mass
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Arndt F Schilling | Patricia Ducy | Michael Amling | Johannes M Rueger | Shu Takeda | S. Takeda | A. Schilling | C. Vinson | G. Karsenty | M. Amling | P. Ducy | J. Rueger | F. T. Beil | Gerard Karsenty | Matthias Priemel | Frank T Beil | Jianhe Shen | Charles Vinson | M. Priemel | Jianhe Shen | F. Beil
[1] J. Friedman,et al. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[2] G Shimamoto,et al. Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density , 1997, Cell.
[3] J. Flier,et al. Leptin accelerates the onset of puberty in normal female mice. , 1997, The Journal of clinical investigation.
[4] C. Saper,et al. From Lesions to Leptin Hypothalamic Control of Food Intake and Body Weight , 1999, Neuron.
[5] E. Brown,et al. Ubiquitin-related proteins regulate interaction of vimentin intermediate filaments with the plasma membrane. , 1999, Molecular cell.
[6] G. Karsenty,et al. A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development. , 1999, Genes & development.
[7] G. Bray,et al. The effects of subdiaphragmatic vagotomy in rats with ventromedial hypothalamic obesity. , 1977, Endocrinology.
[8] Activation of the JAK-STAT signal transduction pathway by oncostatin-M cultured human and mouse osteoblastic cells. , 1996, Endocrinology.
[9] W. Chung,et al. Fine structure of the murine leptin receptor gene: splice site suppression is required to form two alternatively spliced transcripts. , 1997, Genomics.
[10] D. Eyre,et al. Collagen cross-linking in human bone and articular cartilage. Age-related changes in the content of mature hydroxypyridinium residues. , 1988, The Biochemical journal.
[11] C. Mantzoros,et al. Role of leptin in the neuroendocrine response to fasting , 1996, Nature.
[12] J. Darnell,et al. Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice , 1996, Nature Genetics.
[13] L. Melton,et al. Chapter 21 – Magnitude and Impact of Osteoporosis and Fractures , 2001 .
[14] I. Reid. Preventing glucocorticoid-induced osteoporosis. , 1997, The New England journal of medicine.
[15] K. Yasuda,et al. New method for genotyping the mouse Lep(ob) mutation, using a polymerase chain reaction assay. , 1998, Laboratory animal science.
[16] D. Coleman,et al. Laboratory animals exhibiting obesity and diabetes syndromes. , 1977, Metabolism: clinical and experimental.
[17] M. Jensen,et al. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. , 1999, Endocrinology.
[18] A. Inui. Feeding and body-weight regulation by hypothalamic neuropeptides—mediation of the actions of leptin , 1999, Trends in Neurosciences.
[19] M. Maffei,et al. Positional cloning of the mouse obese gene and its human homologue , 1994, Nature.
[20] J. Friedman,et al. Abnormal splicing of the leptin receptor in diabetic mice , 1996, Nature.
[21] R. Palmiter,et al. Attenuation of the Obesity Syndrome of ob/ob Mice by the Loss of Neuropeptide Y , 1996, Science.
[22] J. Flier,et al. Printed in U.S.A. Copyright © 1999 by The Endocrine Society Regulation of Neuronal and Glial Proteins by Leptin: Implications for Brain Development* , 2022 .
[23] J. Flier,et al. Identification of SOCS-3 as a potential mediator of central leptin resistance. , 1998, Molecular cell.
[24] J. Kaufman,et al. Bone mineral status in growth hormone-deficient males with isolated and multiple pituitary deficiencies of childhood onset. , 1992, The Journal of clinical endocrinology and metabolism.
[25] R. Baron,et al. Rescue of the Skeletal Phenotype of Vitamin D Receptor-Ablated Mice in the Setting of Normal Mineral Ion Homeostasis: Formal Histomorphometric and Biomechanical Analyses1. , 1999, Endocrinology.
[26] T. Martin,et al. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. , 1999, Endocrine reviews.
[27] B. Spiegelman,et al. Adipogenesis and Obesity: Rounding Out the Big Picture , 1996, Cell.
[28] Everett M. Rogers,et al. Consensus Development Conference , 1984 .
[29] R. Considine,et al. Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance , 1996, The Lancet.
[30] T. Martin,et al. A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro. , 1998, Endocrinology.
[31] F. Chehab,et al. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin , 1996, Nature Genetics.
[32] C. Christiansen,et al. Low Body Mass Index Is an Important Risk Factor for Low Bone Mass and Increased Bone Loss in Early Postmenopausal Women , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[33] R. Considine,et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. , 1996, The New England journal of medicine.
[34] E. Ravussin,et al. Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects , 1995, Nature Medicine.
[35] Rene Devos,et al. Identification and expression cloning of a leptin receptor, OB-R , 1995, Cell.
[36] J J Anderson,et al. Effects of weight and body mass index on bone mineral density in men and women: The framingham study , 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[37] M. Olive,et al. Life without white fat: a transgenic mouse. , 1998, Genes & development.
[38] J. Flier,et al. Insulin resistance--mechanisms, syndromes, and implications. , 1991, The New England journal of medicine.
[39] L. Tartaglia,et al. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[40] M. Maffei,et al. Positional cloning of the mouse obese gene and its human homologue , 1995, Nature.
[41] L. Tartaglia,et al. Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice , 1996, Cell.
[42] C. Saper,et al. Leptin activates neurons in ventrobasal hypothalamus and brainstem. , 1997, Endocrinology.
[43] B. L. Riggs,et al. A Unitary Model for Involutional Osteoporosis: Estrogen Deficiency Causes Both Type I and Type II Osteoporosis in Postmenopausal Women and Contributes to Bone Loss in Aging Men , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[44] R. Skoda,et al. Defective STAT signaling by the leptin receptor in diabetic mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[45] M. Drezner,et al. Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee , 1987, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[46] D. Lacey,et al. Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation , 1998, Cell.
[47] J. Halaas,et al. Leptin and the regulation of body weight in mammals , 1998, Nature.
[48] Y. J. Kim,et al. Evidence for B_s^0 -> Lambda_c^+ Lambda-bar pi^- , 2013, 1304.6931.
[49] J. Pouilles,et al. Vertebral postmenopausal bone loss is reduced in overweight women: a longitudinal study in 155 early postmenopausal women. , 1993, The Journal of clinical endocrinology and metabolism.