Ligase Complex Activity via the EDD-DDB1-VPRBP E3 HIV-1 Vpr Protein Inhibits Telomerase
暂无分享,去创建一个
[1] Xin Wang,et al. Dyrk2-associated EDD-DDB1-VprBP E3 Ligase Inhibits Telomerase by TERT Degradation* , 2013, The Journal of Biological Chemistry.
[2] Andrej Sali,et al. Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection , 2011, Nature.
[3] B. Sobhian,et al. SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx , 2011, Nature.
[4] M. Washburn,et al. Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein , 2011, Nature.
[5] S. Deeks,et al. HIV infection, inflammation, immunosenescence, and aging. , 2011, Annual review of medicine.
[6] M. Kogan,et al. HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic intervention , 2011, Retrovirology.
[7] Timothy D. Veenstra,et al. Telomerase modulates Wnt signalling by association with target gene chromatin , 2009, Nature.
[8] Junjie Chen,et al. Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase. , 2009, Nature cell biology.
[9] C. Harley,et al. Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes1 , 2008, The Journal of Immunology.
[10] L. Zon,et al. A Non-Canonical Function of Zebrafish Telomerase Reverse Transcriptase Is Required for Developmental Hematopoiesis , 2008, PloS one.
[11] F. Margottin-Goguet,et al. Assembly with the Cul4A-DDB1DCAF1 Ubiquitin Ligase Protects HIV-1 Vpr from Proteasomal Degradation* , 2008, Journal of Biological Chemistry.
[12] J. Chen,et al. VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation , 2008, Oncogene.
[13] M. Lako,et al. A Key Role for Telomerase Reverse Transcriptase Unit in Modulating Human Embryonic Stem Cell Proliferation, Cell Cycle Dynamics, and In Vitro Differentiation , 2008, Stem cells.
[14] Xiao-Fang Yu,et al. DDB1 and Cul4A Are Required for Human Immunodeficiency Virus Type 1 Vpr-Induced G2 Arrest , 2007, Journal of Virology.
[15] A. Finzi,et al. HIV-1 Vpr-Mediated G2 Arrest Involves the DDB1-CUL4AVPRBP E3 Ubiquitin Ligase , 2007, PLoS pathogens.
[16] E. Bonmassar,et al. Telomerase activity, hTERT expression, and phosphorylation are downregulated in CD4+ T lymphocytes infected with human immunodeficiency virus type 1 (HIV‐1) , 2007, Journal of medical virology.
[17] Jean-Christophe Rain,et al. HIV1 Vpr Arrests the Cell Cycle by Recruiting DCAF1/VprBP, a Receptor of the Cul4-DDB1 Ubiquitin Ligase , 2007, Cell cycle.
[18] C. Autexier,et al. The structure and function of telomerase reverse transcriptase. , 2006, Annual review of biochemistry.
[19] H. Salomón,et al. HIV-1 infection downregulates nuclear telomerase activity on lymphoblastoic cells without affecting the enzymatic components at the transcriptional level. , 2006, AIDS research and human retroviruses.
[20] M. Lako,et al. Overexpression of Telomerase Confers Growth Advantage, Stress Resistance, and Enhanced Differentiation of ESCs Toward the Hematopoietic Lineage , 2005, Stem cells.
[21] T. Cech. Beginning to Understand the End of the Chromosome , 2004, Cell.
[22] Yunkai Yu,et al. Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex , 2003, Science.
[23] M. Malim,et al. The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif , 2003, Nature Medicine.
[24] M. Marin,et al. HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation , 2003, Nature Medicine.
[25] P. Nghiem,et al. Activation of the ATR-mediated DNA Damage Response by the HIV-1 Viral Protein R* , 2003, Journal of Biological Chemistry.
[26] A. Badley,et al. Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis. , 2003, The Journal of clinical investigation.
[27] B. Roques,et al. NMR structure of the HIV-1 regulatory protein VPR. , 2003, Journal of molecular biology.
[28] M. Blasco,et al. Cooperation between p53 Mutation and High Telomerase Transgenic Expression in Spontaneous Cancer Development , 2002, Molecular and Cellular Biology.
[29] Robert A. Weinberg,et al. Telomerase contributes to tumorigenesis by a telomere length-independent mechanism , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[30] R. DePinho,et al. Constitutive telomerase expression promotes mammary carcinomas in aging mice , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[31] P. Bostik,et al. Effect of productive in vitro human immunodeficiency virus or simian immunodeficiency virus infection on telomerase activity in lymphoid and nonlymphoid cells. , 2002, The Journal of infectious diseases.
[32] L. Chieco‐Bianchi,et al. Human immunodeficiency virus type 1 modulates telomerase activity in peripheral blood lymphocytes. , 2001, The Journal of infectious diseases.
[33] D. Thomas,et al. A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif. , 1998, Molecular cell.
[34] C. Harley,et al. Extension of life-span by introduction of telomerase into normal human cells. , 1998, Science.
[35] R. Weinberg,et al. hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization , 1997, Cell.
[36] N. Saksena,et al. Gene defects clustered at the C-terminus of the vpr gene of HIV-1 in long-term nonprogressing mother and child pair: in vivo evolution of vpr quasispecies in blood and plasma. , 1996, Virology.
[37] O. Narayan,et al. Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein. , 1994, The Journal of biological chemistry.
[38] C. Harley,et al. Telomeres shorten during ageing of human fibroblasts , 1990, Nature.
[39] E. Blackburn,et al. Functional evidence for an RNA template in telomerase. , 1990, Science.