Bilateral Symmetric Dumbbell C1-C2 Ganglioneuroma in Neurofibromatosis Type 1 Patient Causing Spastic Quadriparesis

Introduction: Ganglioneuroma is a very rare tumor and rarely found bilaterally in association with neurofibromatosis patient. Very few cases of dumbbell ganglioneuroma in the cervical region have been reported in the literature. Materials and methods: A 36-year young male presented to us with a complaint of progressive spastic quadriparesis for 4 years. We did MRI of the cervical spine with contrast and found bilateral symmetrical dumbbell mass at the C1-C2 level severely compressing the spinal cord. Rest of the spine and brain imaging showed normal findings. Result: We operated the patient. Bilateral decompression of the cervical spine at the corresponding level was achieved by complete removal of tumor. Patient’s motor power of all limbs gradually improved. Histopathology was done which revealed ganglioneuroma of both the resected tumors. Conclusion: Bilateral symmetric dumbbell ganglioneuroma is extremely rare in C1-C2 region and can be associated with neurofibromatosis Type 1.