CCR2+ monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice
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José-Alain Sahel | Jean-Louis Bourges | Francine Behar-Cohen | J. Sahel | X. Guillonneau | F. Behar-Cohen | N. Van Rooijen | Constance Auvynet | I. Charo | C. Combadière | F. Sennlaub | L. Poupel | N. Saederup | E. Nandrot | J. Bourges | Lucie Poupel | Israel F Charo | Nico Van Rooijen | Florian Sennlaub | Serge Camelo | Constance Auvynet | Bertrand Calippe | Sophie Lavalette | Shulong J Hu | Elisa Dominguez | Olivier Levy | Elodie Guyon | Noah Saederup | Emeline Nandrot | Xavier Guillonneau | William Raoul | Christophe Combadiere | W. Raoul | B. Calippe | S. Hu | S. Lavalette | Olivier Levy | S. Camelo | E. Dominguez | E. Guyon | Noah Saederup
[1] Silvano Sozzani,et al. The chemokine system in diverse forms of macrophage activation and polarization. , 2004, Trends in immunology.
[2] F. Behar-Cohen,et al. Lipid-Bloated Subretinal Microglial Cells Are at the Origin of Drusen Appearance in CX3CR1-Deficient Mice , 2008, Ophthalmic Research.
[3] D. Fitzgerald,et al. Para‐inflammation‐mediated retinal recruitment of bone marrow‐derived myeloid cells following whole‐body irradiation is CCL2 dependent , 2012, Glia.
[4] N. Van Rooijen,et al. Subpopulations of Mouse Blood Monocytes Differ in Maturation Stage and Inflammatory Response1 , 2004, The Journal of Immunology.
[5] J. Newcombe,et al. Expression of monocyte chemoattractant protein-1 and other β-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions , 1998, Journal of Neuroimmunology.
[6] B S Hawkins,et al. Epidemiology of age-related macular degeneration. , 1999, Molecular vision.
[7] L. Molday,et al. Peripherin. A rim-specific membrane protein of rod outer segment discs. , 1987, Investigative ophthalmology & visual science.
[8] J. Sinsheimer,et al. Association of Sequence Variation in the CX3CR1 Gene with Geographic Atrophy Age-related Macular Degeneration in a Greek Population , 2012, Current eye research.
[9] M. Merad,et al. Studying the mononuclear phagocyte system in the molecular age , 2011, Nature Reviews Immunology.
[10] E. Rakoczy,et al. The effects of age and Cx3cr1 deficiency on retinal microglia in the Ins2(Akita) diabetic mouse. , 2013, Investigative ophthalmology & visual science.
[11] J. Forrester,et al. Dysregulation in Retinal Para-Inflammation and Age-Related Retinal Degeneration in CCL2 or CCR2 Deficient Mice , 2011, PloS one.
[12] R. Ransohoff,et al. The myeloid cells of the central nervous system parenchyma , 2010, Nature.
[13] E. Souied,et al. [Epidemiology of age related macular degeneration]. , 2009, Journal francais d'ophtalmologie.
[14] T. Simon,et al. Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6Chi and Ly6Clo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice , 2008, Circulation.
[15] J. Ott,et al. Complement Factor H Polymorphism in Age-Related Macular Degeneration , 2005, Science.
[16] W. Kuziel,et al. Cc Chemokine Receptor 2 Is Critical for Induction of Experimental Autoimmune Encephalomyelitis , 2000, The Journal of experimental medicine.
[17] E. Chew,et al. The involvement of sequence variation and expression of CX3CR1 in the pathogenesis of age‐related macular degeneration , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[18] G. Kroemer,et al. Clearance of apoptotic photoreceptors: elimination of apoptotic debris into the subretinal space and macrophage-mediated phagocytosis via phosphatidylserine receptor and integrin alphavbeta3. , 2003, The American journal of pathology.
[19] S. Hazen,et al. Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration , 2012, Journal of Cell Science.
[20] Mei Chen,et al. Paraquat-induced retinal degeneration is exaggerated in CX3CR1-deficient mice and is associated with increased retinal inflammation. , 2013, Investigative ophthalmology & visual science.
[21] Ayyakkannu Manivannan,et al. Age‐dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice , 2008, Aging cell.
[22] Robyn H Guymer,et al. Identification of urinary biomarkers for age-related macular degeneration. , 2011, Investigative ophthalmology & visual science.
[23] V. Fadok,et al. Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. , 2002, The Journal of clinical investigation.
[24] G. Conductier,et al. The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases , 2010, Journal of Neuroimmunology.
[25] Markus G. Manz,et al. Development of Monocytes, Macrophages, and Dendritic Cells , 2010, Science.
[26] J. Hu,et al. Polymorphisms in CFH, HTRA1 and CX3CR1 confer risk to exudative age-related macular degeneration in Han Chinese , 2010, British Journal of Ophthalmology.
[27] Livia S. Carvalho,et al. Differential Modulation of Retinal Degeneration by Ccl2 and Cx3cr1 Chemokine Signalling , 2012, PloS one.
[28] J. Provis,et al. Small interfering RNA-mediated suppression of Ccl2 in Müller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration , 2012, Journal of Neuroinflammation.
[29] N. Yoshimura,et al. Knockout of ccr2 alleviates photoreceptor cell death in a model of retinitis pigmentosa. , 2012, Experimental eye research.
[30] M. Miyagi,et al. Photoreceptor Proteins Initiate Microglial Activation via Toll-like Receptor 4 in Retinal Degeneration Mediated by All-trans-retinal* , 2013, The Journal of Biological Chemistry.
[31] R. Ransohoff. Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology. , 2009, Immunity.
[32] A. Nimmerjahn,et al. The Role of Microglia in the Healthy Brain , 2011, The Journal of Neuroscience.
[33] S. E. Barker,et al. The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages. , 2009, Investigative ophthalmology & visual science.
[34] Ronald Klein,et al. Fifteen-year cumulative incidence of age-related macular degeneration: the Beaver Dam Eye Study. , 2007, Ophthalmology.
[35] Steffen Jung,et al. Control of microglial neurotoxicity by the fractalkine receptor , 2006, Nature Neuroscience.
[36] Eiji Sakurai,et al. An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice , 2003, Nature Medicine.
[37] J. Provis,et al. Modulation of major histocompatibility complex class II expression in retinas with age-related macular degeneration. , 1997, Investigative ophthalmology & visual science.
[38] M. Mack,et al. Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. , 2007, The Journal of clinical investigation.
[39] U. Greferath,et al. Ccl2/Cx3cr1 knockout mice have inner retinal dysfunction but are not an accelerated model of AMD. , 2012, Investigative ophthalmology & visual science.
[40] P. Debré,et al. CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. , 2007, The Journal of clinical investigation.
[41] Jose J. Echegaray,et al. Infiltration of Proinflammatory M1 Macrophages into the Outer Retina Precedes Damage in a Mouse Model of Age-Related Macular Degeneration , 2013, International journal of inflammation.
[42] Joan W. Miller,et al. Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis , 2007, Proceedings of the National Academy of Sciences.
[43] T. Hisatomi,et al. The critical role of ocular‐infiltrating macrophages in the development of choroidal neovascularization , 2003, Journal of leukocyte biology.
[44] A. Hofman,et al. The risk and natural course of age-related maculopathy: follow-up at 6 1/2 years in the Rotterdam study. , 2003, Archives of ophthalmology.
[45] S. Sarks,et al. Ageing and degeneration in the macular region: a clinico-pathological study. , 1976, The British journal of ophthalmology.
[46] E. Dratz,et al. The asymmetric transmembrane distribution of phosphatidylethanolamine, phosphatidylserine, and fatty acids of the bovine retinal rod outer segment disk membrane , 2005, The Journal of Membrane Biology.
[47] H. Weiner,et al. Resistance to Experimental Autoimmune Encephalomyelitis in Mice Lacking the Cc Chemokine Receptor (Ccr2) , 2000, The Journal of experimental medicine.
[48] The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood , 2012, The Journal of Immunology.
[49] J. Kowalak,et al. Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration. , 2007, Investigative ophthalmology & visual science.
[50] J. Jonas,et al. Monocyte chemoattractant protein 1, intercellular adhesion molecule 1, and vascular cell adhesion molecule 1 in exudative age-related macular degeneration. , 2010, Archives of ophthalmology.
[51] Hui Zhao,et al. The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes. , 2012, Investigative ophthalmology & visual science.
[52] R. Ransohoff,et al. Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice , 2010, PloS one.
[53] Johanna M Seddon,et al. Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration , 2006, Nature Genetics.
[54] F. Ginhoux,et al. Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages , 2010, Science.
[55] P. Mitchell,et al. A review and meta-analysis of the association between C-reactive protein and age-related macular degeneration. , 2011, Survey of ophthalmology.
[56] Steffen Jung,et al. Blood monocytes consist of two principal subsets with distinct migratory properties. , 2003, Immunity.
[57] Thomas A. Wynn,et al. Macrophage biology in development, homeostasis and disease , 2013, Nature.
[58] N. Van Rooijen,et al. Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis , 2007, The Journal of experimental medicine.
[59] Wei Wang,et al. A new class of membrane-bound chemokine with a CX3C motif , 1997, Nature.
[60] S. J. Myers,et al. Organization and Differential Expression of the Human Monocyte Chemoattractant Protein 1 Receptor Gene , 1997, The Journal of Biological Chemistry.
[61] B. Rollins,et al. Absence of Monocyte Chemoattractant Protein 1 in Mice Leads to Decreased Local Macrophage Recruitment and Antigen-Specific T Helper Cell Type 1 Immune Response in Experimental Autoimmune Encephalomyelitis , 2001, The Journal of experimental medicine.
[62] M. Killingsworth,et al. Evolution of geographic atrophy of the retinal pigment epithelium , 1988, Eye.
[63] F. Behar-Cohen,et al. Role of the chemokine receptor CX3CR1 in the mobilization of phagocytic retinal microglial cells , 2008, Journal of Neuroimmunology.
[64] M. Ruitenberg,et al. Accumulation of murine subretinal macrophages: effects of age, pigmentation and CX3CR1 , 2012, Neurobiology of Aging.
[65] Aaron M. Newman,et al. Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks , 2012, Genome Medicine.
[66] J. Provis,et al. Early focal expression of the chemokine Ccl2 by Müller cells during exposure to damage-inducing bright continuous light. , 2011, Investigative ophthalmology & visual science.
[67] W. Wong,et al. Microglia in the Mouse Retina Alter the Structure and Function of Retinal Pigmented Epithelial Cells: A Potential Cellular Interaction Relevant to AMD , 2009, PloS one.
[68] N. Yoshimura,et al. Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration. , 2008, The American journal of pathology.
[69] J. Gilbert,et al. Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration , 2005, Science.
[70] Amin R. Mazloom,et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages , 2012, Nature Immunology.
[71] P. Libby,et al. Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata. , 2007, The Journal of clinical investigation.
[72] Michel Paques,et al. High resolution fundus imaging by confocal scanning laser ophthalmoscopy in the mouse , 2006, Vision Research.
[73] A. Edwards,et al. Complement Factor H Polymorphism and Age-Related Macular Degeneration , 2005, Science.
[74] A. Milam,et al. Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration. , 2003, Experimental eye research.
[75] P. Debré,et al. Decreased Atherosclerotic Lesion Formation in CX3CR1/Apolipoprotein E Double Knockout Mice , 2003, Circulation.
[76] J. Rosenbaum,et al. Constitutive and inflammatory mediator-regulated fractalkine expression in human ocular tissues and cultured cells. , 2003, Investigative ophthalmology & visual science.
[77] D. Karczewicz,et al. Elevated Plasma Levels of C3a Complement Compound in the Exudative Form of Age-Related Macular Degeneration , 2009, Ophthalmic Research.
[78] Y. Ogura,et al. Inhibition of laser-induced choroidal neovascularization by atorvastatin by downregulation of monocyte chemotactic protein-1 synthesis in mice. , 2007, Investigative ophthalmology & visual science.