Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization and de novo cell types
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D. Stolz | S. Howden | N. Hukriede | M. Little | Haojia Wu | B. Humphreys | O. Cleaver | T. Carroll | S. Sims-Lucas | J. Franks | A. Davidson | S. Watkins | J. Hislop | Aneta Przepiorski | M. Ebrahimkhani | Katherine Pfister | A. Watson | Samira Kiani | J. Maggiore | Anne Silva-Barbosa | Christopher Chaney | Jeremy Velazquez | Ryan LeGraw | Alex D Hill | Evan Streeter | Alex Hill | Katherine E. Pfister | Alan Watson
[1] Xujie Liu,et al. Generation of a doxycycline-inducible ETV2 expression cell line using PiggyBac transposase system. , 2022, Stem Cell Research.
[2] M. Hoogduijn,et al. Creating a kidney organoid-vasculature interaction model using a novel organ-on-chip system , 2022, Scientific Reports.
[3] Ping Liu,et al. Vasculogenesis in kidney organoids upon transplantation , 2022, NPJ Regenerative medicine.
[4] Benjamin S. Freedman. Physiology Assays in Human Kidney Organoids. , 2022, American journal of physiology. Renal physiology.
[5] G. Church,et al. Orthogonally induced differentiation of stem cells for the programmatic patterning of vascularized organoids and bioprinted tissues , 2022, Nature Biomedical Engineering.
[6] D. Cho,et al. Kidney Decellularized Extracellular Matrix Enhanced the Vascularization and Maturation of Human Kidney Organoids , 2022, Advanced science.
[7] S. Quake. The Tabula Sapiens: a multiple organ single cell transcriptomic atlas of humans , 2021, bioRxiv.
[8] B. Chung,et al. Effect of biochemical and biomechanical factors on vascularization of kidney organoid-on-a-chip , 2021, Nano Convergence.
[9] S. Rafii,et al. Developmental angiocrine diversification of endothelial cells for organotypic regeneration. , 2021, Developmental cell.
[10] J. Wetzels,et al. Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling , 2021, bioRxiv.
[11] J. Kellum,et al. Modeling oxidative injury response in human kidney organoids , 2021, Stem cell research & therapy.
[12] I. Banerjee,et al. Enhancing Kidney Vasculature in Tissue Engineering—Current Trends and Approaches: A Review , 2021, Biomimetics.
[13] A. Gupta,et al. Vascular deficiencies in renal organoids and ex vivo kidney organogenesis. , 2021, Developmental biology.
[14] N. Hukriede,et al. A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells. , 2021, Journal of visualized experiments : JoVE.
[15] M. Duncan,et al. A simple method for quantitating confocal fluorescent images , 2021, Biochemistry and biophysics reports.
[16] J. Powell,et al. DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets , 2021, bioRxiv.
[17] Anushya Muruganujan,et al. The Gene Ontology resource: enriching a GOld mine , 2020, Nucleic Acids Res..
[18] D. Ribatti,et al. The role of vascular niche and endothelial cells in organogenesis and regeneration. , 2020, Experimental cell research.
[19] Yuqi Tan,et al. Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids , 2020, Cell systems.
[20] R. A. Gomez,et al. Deciphering the Identity of Renin Cells in Health and Disease. , 2020, Trends in molecular medicine.
[21] N. Hukriede,et al. Protocol for Large-Scale Production of Kidney Organoids from Human Pluripotent Stem Cells , 2020, STAR protocols.
[22] P. Shepherd,et al. Derivation of induced pluripotent stem cell lines from New Zealand donors , 2020, Journal of the Royal Society of New Zealand.
[23] Raphael Gottardo,et al. Integrated analysis of multimodal single-cell data , 2020, Cell.
[24] Duc-Huy T. Nguyen,et al. Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis , 2020, Nature.
[25] G. Hon,et al. Identification and characterization of cellular heterogeneity within the developing renal interstitium , 2020, Development.
[26] E. Hoorn,et al. Human kidney organoids produce functional renin , 2020, Cytotherapy.
[27] Haojia Wu,et al. Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury , 2020, Proceedings of the National Academy of Sciences.
[28] A. Schambach,et al. Inducible Forward Programming of Human Pluripotent Stem Cells to Hemato-endothelial Progenitor Cells with Hematopoietic Progenitor Potential , 2019, Stem cell reports.
[29] S. Rafii,et al. Molecular determinants of nephron vascular specialization in the kidney , 2019, Nature Communications.
[30] F. Hyder,et al. Engineering of human brain organoids with a functional vascular-like system , 2019 .
[31] Tomoyuki Mano,et al. Advanced CUBIC tissue clearing for whole-organ cell profiling , 2019, Nature Protocols.
[32] F. Grosveld,et al. A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury. , 2019, Journal of the American Society of Nephrology : JASN.
[33] D. Marciano. Mesangial Cells: The Tuft Guys of Glomerular Development. , 2019, Journal of the American Society of Nephrology : JASN.
[34] R. Nishinakamura. Human kidney organoids: progress and remaining challenges , 2019, Nature Reviews Nephrology.
[35] Cunchuan Wang,et al. Renal Subcapsular Transplantation of 2'-Deoxyguanosine-Treated Murine Embryonic Thymus in Nude Mice. , 2019, Journal of visualized experiments : JoVE.
[36] A. Ransick,et al. In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. , 2019, Developmental cell.
[37] A. Oshlack,et al. Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk , 2019, Development.
[38] Maaike Nieveen,et al. Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development , 2019, PLoS biology.
[39] N. Jourde-Chiche,et al. Endothelium structure and function in kidney health and disease , 2019, Nature Reviews Nephrology.
[40] Patrick Cahan,et al. SingleCellNet: a computational tool to classify single cell RNA-Seq data across platforms and across species , 2018, bioRxiv.
[41] Kimberly A. Homan,et al. Flow-enhanced vascularization and maturation of kidney organoids in vitro , 2018, Nature Methods.
[42] A. Oshlack,et al. Evaluation of variability in human kidney organoids , 2018, Nature Methods.
[43] A. Oshlack,et al. 3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening , 2018, Nature Communications.
[44] Michael Muntifering,et al. Clearing for Deep Tissue Imaging , 2018, Current protocols in cytometry.
[45] A. Ransick,et al. Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. , 2018, Journal of the American Society of Nephrology : JASN.
[46] A. McMahon,et al. A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells , 2017, bioRxiv.
[47] Hannah A. Pliner,et al. Reversed graph embedding resolves complex single-cell trajectories , 2017, Nature Methods.
[48] D. Mooney,et al. Flow-Induced Vascular Network Formation and Maturation in Three-Dimensional Engineered Tissue. , 2017, ACS biomaterials science & engineering.
[49] R. A. Gomez,et al. Fate of Renin Cells During Development and Disease , 2017, Hypertension.
[50] E. Stanley,et al. A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells , 2016, Stem cell reports.
[51] Grace X. Y. Zheng,et al. Massively parallel digital transcriptional profiling of single cells , 2016, Nature Communications.
[52] O. Cleaver,et al. Blood vessel crosstalk during organogenesis—focus on pancreas and endothelial cells , 2016, Wiley interdisciplinary reviews. Developmental biology.
[53] J. D. Engel,et al. Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect , 2016, Molecular and Cellular Biology.
[54] Andrew D. Rouillard,et al. Enrichr: a comprehensive gene set enrichment analysis web server 2016 update , 2016, Nucleic Acids Res..
[55] Robert G. Parton,et al. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis , 2016, Nature.
[56] Mark A. Skylar-Scott,et al. Three-dimensional bioprinting of thick vascularized tissues , 2016, Proceedings of the National Academy of Sciences.
[57] Linda G. Griffith,et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6 , 2016, Nature Communications.
[58] Dimitri Perrin,et al. Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging , 2015, Nature Protocols.
[59] Yaopan Mao,et al. Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching , 2015, Development.
[60] B. Blencowe,et al. Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool , 2015, Development.
[61] T. Coffman,et al. Tubulovascular cross-talk by vascular endothelial growth factor a maintains peritubular microvasculature in kidney. , 2015, Journal of the American Society of Nephrology : JASN.
[62] O. Elemento,et al. Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells. , 2015, The Journal of clinical investigation.
[63] R. Adams,et al. Regulation of tissue morphogenesis by endothelial cell-derived signals. , 2015, Trends in cell biology.
[64] Nana Shimizu,et al. ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells , 2014, Proceedings of the National Academy of Sciences.
[65] J. Lewis,et al. 3D Bioprinting of Vascularized, Heterogeneous Cell‐Laden Tissue Constructs , 2014, Advanced materials.
[66] Cole Trapnell,et al. The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells , 2014, Nature Biotechnology.
[67] L. Lum,et al. Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation , 2013, Nature Cell Biology.
[68] D. Koya,et al. Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney disease , 2013, Clinical and Experimental Nephrology.
[69] Olivier Elemento,et al. Efficient Direct Reprogramming of Mature Amniotic Cells into Endothelial Cells by ETS Factors and TGFβ Suppression , 2012, Cell.
[70] D. Abrahamson. Role of the podocyte (and glomerular endothelium) in building the GBM. , 2012, Seminars in Nephrology.
[71] Laure Gambardella,et al. A Computational Tool for Quantitative Analysis of Vascular Networks , 2011, PloS one.
[72] A. Kurtz,et al. Physiology of kidney renin. , 2010, Physiological reviews.
[73] Shahin Rafii,et al. Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors , 2010, Nature Reviews Cancer.
[74] M. Bhasin,et al. ERG is required for the differentiation of embryonic stem cells along the endothelial lineage , 2009, BMC Developmental Biology.
[75] F. Braet,et al. Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier , 2009, American journal of physiology. Renal physiology.
[76] E. Crivellato,et al. Contribution of endothelial cells to organogenesis: a modern reappraisal of an old Aristotelian concept , 2007, Journal of anatomy.
[77] R. Wiggins,et al. The spectrum of podocytopathies: a unifying view of glomerular diseases. , 2007, Kidney international.
[78] D. Warburton,et al. VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis. , 2006, Developmental biology.
[79] Qizhi Yao,et al. Shear Stress Induces Endothelial Differentiation From a Murine Embryonic Mesenchymal Progenitor Cell Line , 2005, Arteriosclerosis, thrombosis, and vascular biology.
[80] Li Yuan,et al. Flow regulates arterial-venous differentiation in the chick embryo yolk sac , 2003, Development.
[81] M. Ashburner,et al. Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.
[82] S. Howden,et al. A Toolbox to Characterize Human Induced Pluripotent Stem Cell-Derived Kidney Cell Types and Organoids. , 2019, Journal of the American Society of Nephrology : JASN.
[83] O. Cleaver,et al. Vascularizing organogenesis: Lessons from developmental biology and implications for regenerative medicine. , 2019, Current topics in developmental biology.
[84] K. Tryggvason,et al. The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death. , 2001, Human molecular genetics.