Statistical properties of X-ray phase-contrast tomography

Quantitative in-line X-ray phase-contrast tomography methods seek to reconstruct separate images that depict an object’s absorption and real-valued refractive index distributions. They hold great promise for biomedical applications due to their ability to distinguish soft tissue structures based on their complex X-ray refractive index values. In this work, we investigate the second-order statistical properties of images in phase-contrast tomography and describe how they are distinct from those associated with conventional absorption-based tomography.

[1]  S. Wilkins,et al.  X-ray phase-contrast microscopy and microtomography. , 2003, Optics express.

[2]  Michel Schlenker,et al.  Quantitative phase contrast tomography using coherent synchrotron radiation , 2002, Optics + Photonics.

[3]  David R Pickens,et al.  Characterization of the phase-contrast radiography edge-enhancement effect in a cabinet x-ray system. , 2006, Physics in medicine and biology.

[4]  A. Bronnikov,et al.  Theory of quantitative phase-contrast computed tomography. , 2002, Journal of the Optical Society of America. A, Optics, image science, and vision.

[5]  Kenneth M. Hanson,et al.  The Characteristics of Computed Tomographic Reconstruction Noise and Their Effect on Detectability , 1978, IEEE Transactions on Nuclear Science.

[6]  Kenneth M. Hanson,et al.  The Characteristics of Computed Tomographic Reconstruction Noise and Their Effect on Detectability , 1978 .

[7]  M F Kijewski,et al.  The noise power spectrum of CT images. , 1987, Physics in medicine and biology.

[8]  P. Spanne,et al.  In-line holography and phase-contrast microtomography with high energy x-rays. , 1999, Physics in medicine and biology.

[9]  E Castelli,et al.  Mammography with synchrotron radiation: phase-detection techniques. , 2000, Radiology.

[10]  K. Nugent,et al.  Quantitative phase tomography , 2000 .

[11]  Harrison H. Barrett,et al.  Foundations of Image Science , 2003, J. Electronic Imaging.

[12]  T. Gureyev,et al.  Phase retrieval using coherent imaging systems with linear transfer functions , 2004 .

[13]  S. Wilkins,et al.  Linear algorithms for phase retrieval in the Fresnel region , 2004 .

[14]  David R Pickens,et al.  Dual focal-spot imaging for phase extraction in phase-contrast radiography. , 2003, Medical physics.

[15]  R. F. Wagner,et al.  Unified SNR analysis of medical imaging systems , 1985, Physics in medicine and biology.

[16]  Dean Chapman,et al.  Recent advances in synchrotron radiation medical research , 2005 .

[17]  R. Lewis,et al.  Medical phase contrast x-ray imaging: current status and future prospects. , 2004, Physics in medicine and biology.

[18]  S. Fiedler,et al.  Imaging lobular breast carcinoma: comparison of synchrotron radiation DEI-CT technique with clinical CT, mammography and histology. , 2004, Physics in medicine and biology.