Effects and mechanisms of berberine in diabetes treatment
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[1] Jin-Yuarn Lin,et al. Protective effect of berberine on serum glucose levels in non-obese diabetic mice. , 2012, International immunopharmacology.
[2] Qiang Li,et al. Berberine alleviates ischemic arrhythmias via recovering depressed I(to) and I(Ca) currents in diabetic rats. , 2012, Phytomedicine : international journal of phytotherapy and phytopharmacology.
[3] Xiaojun Meng,et al. [Research on therapeutic effect and hemorrheology change of berberine in new diagnosed patients with type 2 diabetes combining nonalcoholic fatty liver disease]. , 2011, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
[4] Jianan Wang,et al. Preparation of an anhydrous reverse micelle delivery system to enhance oral bioavailability and anti-diabetic efficacy of berberine. , 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[5] Christina Plaisier,et al. Berberine acutely activates the glucose transport activity of GLUT1. , 2011, Biochimie.
[6] Jin-Yuarn Lin,et al. Berberine, an isoquinoline alkaloid in herbal plants, protects pancreatic islets and serum lipids in nonobese diabetic mice. , 2011, Journal of agricultural and food chemistry.
[7] Junling Han,et al. Modulating gut microbiota as an anti-diabetic mechanism of berberine , 2011, Medical science monitor : international medical journal of experimental and clinical research.
[8] P. Bhutada,et al. Protection of cholinergic and antioxidant system contributes to the effect of berberine ameliorating memory dysfunction in rat model of streptozotocin-induced diabetes , 2011, Behavioural Brain Research.
[9] Hua Zhu,et al. Berberine-improved visceral white adipose tissue insulin resistance associated with altered sterol regulatory element-binding proteins, liver x receptors, and peroxisome proliferator-activated receptors transcriptional programs in diabetic hamsters. , 2011, Biological & pharmaceutical bulletin.
[10] Jiyin Zhou,et al. Protective effect of berberine on antioxidant enzymes and positive transcription elongation factor b expression in diabetic rat liver. , 2011, Fitoterapia.
[11] Jianping Ye,et al. Berberine Improves Glucose Metabolism in Diabetic Rats by Inhibition of Hepatic Gluconeogenesis , 2011, PloS one.
[12] C. Beaurepaire,et al. Hypoglycemic and insulin-sensitizing effects of berberine in high-fat diet- and streptozotocin-induced diabetic rats. , 2011, Metabolism: clinical and experimental.
[13] Qiang Li,et al. Berberine elicits anti‐arrhythmic effects via IK1/Kir2.1 in the rat type 2 diabetic myocardial infarction model , 2011, Phytotherapy research : PTR.
[14] Shiwen Zhou,et al. Berberine regulates peroxisome proliferator-activated receptors and positive transcription elongation factor b expression in diabetic adipocytes. , 2010, European journal of pharmacology.
[15] M. Zeitz,et al. TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling , 2010, Journal of Cell Science.
[16] T. Egawa,et al. Berberine-induced activation of 5'-adenosine monophosphate-activated protein kinase and glucose transport in rat skeletal muscles. , 2010, Metabolism: clinical and experimental.
[17] Suowen Xu,et al. Berberine ameliorates renal injury in diabetic C57BL/6 mice: Involvement of suppression of SphK-S1P signaling pathway. , 2010, Archives of biochemistry and biophysics.
[18] M. Gu,et al. 8,8-Dimethyldihydroberberine with improved bioavailability and oral efficacy on obese and diabetic mouse models. , 2010, Bioorganic & medicinal chemistry.
[19] Zhaoyong Hu,et al. Atrogin-1 Affects Muscle Protein Synthesis and Degradation When Energy Metabolism Is Impaired by the Antidiabetes Drug Berberine , 2010, Diabetes.
[20] Chih-Hsin Tang,et al. Berberine suppresses neuroinflammatory responses through AMP‐activated protein kinase activation in BV‐2 microglia , 2010, Journal of cellular biochemistry.
[21] Xiao-dong Liu,et al. Berberine suppresses intestinal disaccharidases with beneficial metabolic effects in diabetic states, evidences from in vivo and in vitro study , 2010, Naunyn-Schmiedeberg's Archives of Pharmacology.
[22] Wei-Jia Kong,et al. Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. , 2010, Metabolism: clinical and experimental.
[23] Jing Li,et al. Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin. , 2009, European journal of pharmacology.
[24] Guoliang Cui,et al. Berberine Differentially Modulates the Activities of ERK, p38 MAPK, and JNK to Suppress Th17 and Th1 T Cell Differentiation in Type 1 Diabetic Mice* , 2009, The Journal of Biological Chemistry.
[25] W. Jia,et al. [Study on effects of baicalin, berberine and Astragalus polysaccharides and their combinative effects on aldose reductase in vitro]. , 2009, Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
[26] A. Xu,et al. Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase. , 2009, Cardiovascular research.
[27] J. B. Kim,et al. Berberine suppresses proinflammatory responses through AMPK activation in macrophages. , 2009, American journal of physiology. Endocrinology and metabolism.
[28] M. Lane,et al. Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity. , 2009, American journal of physiology. Endocrinology and metabolism.
[29] Kebin Zhang,et al. Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats. , 2009, European journal of pharmacology.
[30] Peiqing Liu,et al. Berberine reduces fibronectin and collagen accumulation in rat glomerular mesangial cells cultured under high glucose condition , 2009, Molecular and Cellular Biochemistry.
[31] Michael P. Murphy,et al. How mitochondria produce reactive oxygen species , 2008, The Biochemical journal.
[32] Wei Zhang,et al. Anti-diabetic effects of cinnamaldehyde and berberine and their impacts on retinol-binding protein 4 expression in rats with type 2 diabetes mellitus. , 2008, Chinese medical journal.
[33] Xiao Wang,et al. Berberine acutely inhibits insulin secretion from beta-cells through 3',5'-cyclic adenosine 5'-monophosphate signaling pathway. , 2008, Endocrinology.
[34] F. Lu,et al. [Effects of berberine on expression of hepatocyte nuclear factor 4alpha and glucokinase activity in mouse primary hepatocytes]. , 2008, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
[35] Shufeng Zhou,et al. Berberine inhibits aldose reductase and oxidative stress in rat mesangial cells cultured under high glucose. , 2008, Archives of biochemistry and biophysics.
[36] G. Ning,et al. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. , 2008, The Journal of clinical endocrinology and metabolism.
[37] Le Zhang,et al. Chronic effects of berberine on blood, liver glucolipid metabolism and liver PPARs expression in diabetic hyperlipidemic rats. , 2008, Biological & pharmaceutical bulletin.
[38] Jianping Ye,et al. Efficacy of berberine in patients with type 2 diabetes mellitus. , 2008, Metabolism: clinical and experimental.
[39] Shousi Lu,et al. Berberine attenuates intestinal disaccharidases in streptozotocin-induced diabetic rats. , 2008, Die Pharmazie.
[40] Weihua Liu,et al. Berberine ameliorates renal injury in streptozotocin-induced diabetic rats by suppression of both oxidative stress and aldose reductase. , 2008, Chinese medical journal.
[41] D. James,et al. Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I , 2008, Diabetes.
[42] Hyun-Joung Lim,et al. Berberine-induced LDLR up-regulation involves JNK pathway. , 2007, Biochemical and biophysical research communications.
[43] P. Bénit,et al. Targeted Deletion of AIF Decreases Mitochondrial Oxidative Phosphorylation and Protects from Obesity and Diabetes , 2007, Cell.
[44] C. Hyun,et al. Berberine activates GLUT1-mediated glucose uptake in 3T3-L1 adipocytes. , 2007, Biological & pharmaceutical bulletin.
[45] Xiao Wang,et al. Berberine stimulates glucose transport through a mechanism distinct from insulin. , 2007, Metabolism: clinical and experimental.
[46] L. Rovati,et al. Eulipidemic Effects of Berberine Administered Alone or in Combination with Other Natural Cholesterol-lowering Agents , 2007, Arzneimittelforschung.
[47] Ji-won Park,et al. Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte , 2006, Experimental & Molecular Medicine.
[48] Wei Wei,et al. Effects of berberine on diabetes induced by alloxan and a high-fat/high-cholesterol diet in rats. , 2006, Journal of ethnopharmacology.
[49] M. Gu,et al. Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK. , 2006, Biochimica et biophysica acta.
[50] Yuebo Zhang,et al. Berberine inhibits 3T3-L1 adipocyte differentiation through the PPARγ pathway , 2006 .
[51] D. James,et al. Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States , 2006, Diabetes.
[52] J. Brusq,et al. Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine Published, JLR Papers in Press, February 28, 2006. , 2006, Journal of Lipid Research.
[53] Hyun-Joung Lim,et al. Berberine inhibits rat vascular smooth muscle cell proliferation and migration in vitro and improves neointima formation after balloon injury in vivo. Berberine improves neointima formation in a rat model. , 2006, Atherosclerosis.
[54] C. Ting,et al. Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury. , 2006, Biochemical pharmacology.
[55] Jingwen Liu,et al. Extracellular Signal-Regulated Kinase–Dependent Stabilization of Hepatic Low-Density Lipoprotein Receptor mRNA by Herbal Medicine Berberine , 2005, Arteriosclerosis, thrombosis, and vascular biology.
[56] J. Castillo,et al. LED fluorescence spectroscopy for direct determination of monoamine oxidase B inactivation. , 2005, Analytical biochemistry.
[57] Sunmin Park,et al. Insulin sensitizing and insulinotropic action of berberine from Cortidis rhizoma. , 2005, Biological & pharmaceutical bulletin.
[58] Satoru Inaba,et al. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins , 2004, Nature Medicine.
[59] Weihua Chen,et al. [Effect of Astragalus polysaccharides and berberine on carbohydrate metabolism and cell differentiation in 3T3-L1 adipocytes]. , 2004, Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
[60] D. Hardie,et al. AMP-Activated Protein Kinase: A Master Switch in Glucose and Lipid Metabolism , 2004, Reviews in Endocrine and Metabolic Disorders.
[61] F. Lu,et al. Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion. , 2004, Acta pharmacologica Sinica.
[62] J. Arrabaça,et al. Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids. , 2003, Toxicology letters.
[63] Guang-Ji Wang,et al. [Inhibitory action of berberine on glucose absorption]. , 2003, Yao xue xue bao = Acta pharmaceutica Sinica.
[64] J. P. Fawcett,et al. The antihyperglycaemic activity of berberine arises from a decrease of glucose absorption. , 2003, Planta medica.
[65] Xiao Wang,et al. [Effect of berberine on the differentiation of adipocyte]. , 2003, Zhonghua yi xue za zhi.
[66] Feng-ying Li,et al. Effects of berberine on glucose metabolism in vitro. , 2002, Metabolism: clinical and experimental.
[67] R. Tan,et al. Monoamine Oxidase Inhibitors from Rhizoma of Coptis chinensis , 2001, Planta medica.
[68] Ni Yx. Therapeutic effect of berberine on 60 patients with type II diabetes mellitus and experimental research , 1988 .
[69] V. Mikes,et al. Interaction of fluorescent berberine alkyl derivatives with respiratory chain of rat liver mitochondria , 1985, Journal of bioenergetics and biomembranes.
[70] V. Mikes,et al. Berberine derivatives as cationic fluorescent probes for the investigation of the energized state of mitochondria. , 1983, Biochimica et biophysica acta.
[71] Hua Zhu,et al. Beneficial effect of berberine on hepatic insulin resistance in diabetic hamsters possibly involves in SREBPs, LXRα and PPARα transcriptional programs. , 2010, Endocrine journal.
[72] Zhou Shi-wen. Effect of berberine on CDK9 and cyclin T1 expression in skeletal muscle of diabetic rats induced by streptozotocin and a high-carbohydrate/high-fat diet , 2008 .
[73] Jianping Ye,et al. Berberine improves glucose metabolism through induction of glycolysis. , 2008, American journal of physiology. Endocrinology and metabolism.
[74] Jiyin Zhou,et al. Effect of berberine on glucolipid metabolization in diabetic skeletal muscle and its mechanism , 2007 .
[75] Yuebo Zhang,et al. Berberine inhibits 3T3-L1 adipocyte differentiation through the PPARgamma pathway. , 2006, Biochemical and biophysical research communications.
[76] D. Hardie,et al. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. , 2005, Cell metabolism.
[77] C. Ming. Effects of berberine on glucose and lipid metabolism in animal experiment , 2004 .
[78] Y. Ying. Effects of Berberine on Lipid Metabolism in Rats , 2003 .
[79] M. D. Faddeeva,et al. [Inhibition of liver mitochondrial monoamine oxidase activity by alkaloids isolated from Chelidonium and Macleaya and by their derivative drugs]. , 2003, Tsitologiia.
[80] Y. Ni. [Therapeutic effect of berberine on 60 patients with type II diabetes mellitus and experimental research]. , 1988, Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine.