A DNA expression array to detect toxic stress response in European flounder (Platichthys flesus).

[1]  K. Chipman,et al.  Isolation of differentially expressed genes from contaminant exposed European flounder by suppressive, subtractive hybridisation. , 2004, Marine environmental research.

[2]  C. Hogstrand,et al.  Application of genomics and proteomics for study of the integrated response to zinc exposure in a non-model fish species, the rainbow trout. , 2002, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[3]  J. Kelso,et al.  Gene expression analysis of largemouth bass exposed to estradiol, nonylphenol, and p,p'-DDE. , 2002, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[4]  G. Churchill,et al.  Variation in gene expression within and among natural populations , 2002, Nature Genetics.

[5]  C. V. van Noorden,et al.  Sex-specific biotransformation and detoxification after xenobiotic exposure of primary cultured hepatocytes of European flounder (Platichthys flesus L.). , 2002, Aquatic toxicology.

[6]  V. Dzau,et al.  Construction of a zebrafish cDNA microarray: gene expression profiling of the zebrafish during development. , 2002, Biochemical and biophysical research communications.

[7]  M. Leaver,et al.  Allelic variations in the plaice UGT1B1 gene. , 2002, Marine environmental research.

[8]  L. Folmar,et al.  Array technology as a tool to monitor exposure of fish to xenoestrogens. , 2002, Marine environmental research.

[9]  Zhanjiang Liu,et al.  Differential gene expression in the brain of channel catfish (Ictalurus punctatus) in response to cold acclimation , 2002, Molecular Genetics and Genomics.

[10]  C. Proud,et al.  Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors. , 2002, European journal of biochemistry.

[11]  C. Norbury,et al.  Sum1, a component of the fission yeast eIF3 translation initiation complex, is rapidly relocalized during environmental stress and interacts with components of the 26S proteasome. , 2002, Molecular biology of the cell.

[12]  C. V. van Noorden,et al.  Glucose-6-phosphate dehydrogenase: the key to sex-related xenobiotic toxicity in hepatocytes of European flounder (Platichthys flesus L.)? , 2002, Aquatic toxicology.

[13]  P. Joseph,et al.  Oncogenic Potential of Mouse Translation Elongation Factor-1δ, a Novel Cadmium-responsive Proto-oncogene* , 2002, The Journal of Biological Chemistry.

[14]  K. Kliche,et al.  Circadian variation of dihydropyrimidine dehydrogenase mRNA expression in leukocytes and serum cortisol levels in patients with advanced gastrointestinal carcinomas compared to healthy controls , 2002, Journal of Cancer Research and Clinical Oncology.

[15]  H. Lehrach,et al.  Identification of nodal signaling targets by array analysis of induced complex probes , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

[16]  R Herwig,et al.  Statistical evaluation of differential expression on cDNA nylon arrays with replicated experiments. , 2001, Nucleic acids research.

[17]  S. Anderson,et al.  Effects of contaminants on genetic patterns in aquatic organisms: a review. , 2001, Mutation research.

[18]  A. Ellis Innate host defense mechanisms of fish against viruses and bacteria. , 2001, Developmental and comparative immunology.

[19]  F. Gil,et al.  Immunohistochemical evidence for the expression and induction of paraoxonase in rat liver, kidney, lung and brain tissue. Implications for its physiological role. , 2001, Chemico-biological interactions.

[20]  J. Rotchell,et al.  Hepatic metallothionein as a biomaker for metal contamination: age effects and seasonal variation in European flounders (Pleuronectes flesus) from the Severn Estuary and Bristol Channel. , 2001, Marine environmental research.

[21]  L. Folmar,et al.  Multiple responses in gene expression in fish treated with estrogen. , 2001, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[22]  R. Stagg,et al.  Measurement of cytochrome P4501A induction in dab (Limanda limanda) and other teleosts with species-specific cDNA probes: isolation and characterisation of dab cDNA and its use in expression studies with beta-naphthoflavone-treated fish. , 2001, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

[23]  L. Gerwick,et al.  Immune-relevant (including acute phase) genes identified in the livers of rainbow trout, Oncorhynchus mykiss, by means of suppression subtractive hybridization. , 2001, Developmental and comparative immunology.

[24]  Y. Wang,et al.  Target gene search for the metal-responsive transcription factor MTF-1. , 2001, Nucleic acids research.

[25]  G. Somero,et al.  Hypoxia-induced gene expression profiling in the euryoxic fish Gillichthys mirabilis. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[26]  S. Penn,et al.  Applications of gene arrays in environmental toxicology: fingerprints of gene regulation associated with cadmium chloride, benzo(a)pyrene, and trichloroethylene. , 2000, Environmental health perspectives.

[27]  C. Norbury,et al.  A fission yeast homolog of Int-6, the mammalian oncoprotein and eIF3 subunit, induces drug resistance when overexpressed. , 2000, Molecular biology of the cell.

[28]  N. Sonenberg,et al.  Internal ribosome initiation of translation and the control of cell death. , 2000, Trends in genetics : TIG.

[29]  D. O. Norris,et al.  Some aspects of hepatic function in feral brown trout, Salmo trutta, living in metal contaminated water. , 2000, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

[30]  M. Gore,et al.  Gene expression changes associated with cytotoxicity identified using cDNA arrays , 2000, Functional & Integrative Genomics.

[31]  J. S. Lee,et al.  The cytochrome P450 1A gene (CYP1A) from European flounder (Platichthys flesus), analysis of regulatory regions and development of a dual luciferase reporter gene system. , 2000, Marine environmental research.

[32]  J. S. Lee,et al.  Analysis of mutations in the p53 tumor suppressor gene and Ki- and Ha-ras proto-oncogenes in hepatic tumors of European flounder (Platichthys flesus). , 2000, Marine environmental research.

[33]  F. Banine,et al.  Positive and negative elements modulate the promoter of the human liver-specific alpha2-HS-glycoprotein gene. , 2000, European journal of biochemistry.

[34]  J. Chipman,et al.  Cloning of the β-Actin Gene from the European Flounder (Platichthys flesus L.) , 2000 .

[35]  S Rozen,et al.  Primer3 on the WWW for general users and for biologist programmers. , 2000, Methods in molecular biology.

[36]  M. Kirby,et al.  The detection of biomarkers of genotoxin exposure in the European flounder (Platichthys flesus) collected from the River Tyne Estuary. , 1999, Mutation research.

[37]  A. Parikh,et al.  Stress response decreases the interleukin-1beta-induced production of complement component C3 in human intestinal epithelial cells. , 1999, Clinical science.

[38]  M. Hentze,et al.  Inactivation of Both RNA Binding and Aconitase Activities of Iron Regulatory Protein-1 by Quinone-induced Oxidative Stress* , 1999, The Journal of Biological Chemistry.

[39]  H. Steinhart,et al.  Induction of DNA Strand Breaks and Expression of HSP70 and GRP78 Homolog by Cadmium in the Marine Sponge Suberites domuncula , 1999, Archives of environmental contamination and toxicology.

[40]  J. Bergé,et al.  Molecular cloning of a CYP1A cDNA from the teleost fish Dicentrarchus labrax. , 1998, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

[41]  M. Sogin,et al.  Molecular cloning of CYP1A from the estuarine fish Fundulus heteroclitus and phylogenetic analysis of CYP1 genes: update with new sequences. , 1998, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

[42]  A. Falus,et al.  Cytokine regulation of the acute‐phase protein levels in multiple myeloma , 1998, European journal of clinical investigation.

[43]  P. Bjerregaard,et al.  Estrogenicity of xenobiotics in rainbow trout (Oncorhynchus mykiss) using in vivo synthesis of vitellogenin as a biomarker , 1998 .

[44]  J. Chipman,et al.  Cloning of genomic p53 from European flounder (Platichthys flesus) , 1998 .

[45]  A. Köhler,et al.  Aldehyde dehydrogenase and glucose-6-phosphate dehydrogenase as markers for enzyme-altered foci in the liver of dab (Limanda limanda L.) , 1998 .

[46]  B. Sergeyev,et al.  Cytochrome P450 system and heme synthesis enzymes activity in flounder liver as biomarkers of marine environments pollution , 1998 .

[47]  M. Leaver,et al.  Structural Studies of a UDP-glucuronosyltransferase gene from the plaice (Pleuronectes platessa) , 1998 .

[48]  T. Collier,et al.  Quantitation of CYP1A expression in two flatfish species showing different prevalences of contaminant-induced hepatic disease , 1998 .

[49]  M. Sandvik,et al.  Natural modulation of hepatic metallothionein and cytochrome P4501A in flounder, Platichthys flesus L. , 1998 .

[50]  M. E. Hahn,et al.  Low inducibility of CYP1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): characterization of the Ah receptor and the role of CYP1A inhibition. , 1998, Toxicological sciences : an official journal of the Society of Toxicology.

[51]  G. Whale,et al.  An assessment of sediment toxicity in the River Tyne Estuary, UK by means of bioassays , 1998 .

[52]  Hong Liu,et al.  Endoplasmic Reticulum Chaperones GRP78 and Calreticulin Prevent Oxidative Stress, Ca2+ Disturbances, and Cell Death in Renal Epithelial Cells* , 1997, The Journal of Biological Chemistry.

[53]  J. Stevens,et al.  Reduction of trans-4,5-Dihydroxy-1,2-dithiane by Cellular Oxidoreductases Activates gadd153/chop andgrp78 Transcription and Induces Cellular Tolerance in Kidney Epithelial Cells* , 1997, The Journal of Biological Chemistry.

[54]  Morten Sandvik Jonny Beyer Anders Goksøyr Ketil Hy Interaction of benzo[a]pyrene, 2,3,3',4,4',5 hexachlorobiphenyl (PCB 156) and cadmium on biomarker responses in flounder (Platichthys flesus L.). , 1997, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

[55]  D. Livingstone,et al.  Responses of hepatic biotransformation and antioxidant enzymes to CYP1A-inducers (3-methylcholanthrene, β-naphthoflavone) in sea bass (Dicentrarchus labrax), dab (Limanda limanda) and rainbow trout (Oncorhynchus mykiss) , 1996 .

[56]  S. Courtenay,et al.  A comparison of cytochrome P4501A (CYP1A) mRNA inducibility in four species of Atlantic coast anadromous fishes , 1996 .

[57]  B. La Du,et al.  The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family. , 1996, Genomics.

[58]  J. Albaigés,et al.  Effects of the “Aegean Sea” oil spill on biotransformation enzymes, oxidative stress and DNA-adducts in digestive gland of the mussel (Mytilus edulus L.) , 1996 .

[59]  A. Bainy,et al.  Oxidative stress in gill, erythrocytes, liver and kidney of Nile tilapia (Oreochromis niloticus) from a polluted site , 1996 .

[60]  A. Goksøyr,et al.  Biomarker responses in flounder (Platichthys flesus) and their use in pollution monitoring , 1996 .

[61]  L. Penland,et al.  Use of a cDNA microarray to analyse gene expression patterns in human cancer , 1996, Nature Genetics.

[62]  I. Wirgin,et al.  Characterization and prevalence of a polymorphism in the 3' untranslated region of cytochrome P4501A1 in cancer-prone Atlantic tomcod. , 1995, Archives of biochemistry and biophysics.

[63]  M. Sogin,et al.  Identification of cytochrome P-450 1A (CYP1A) genes from two teleost fish, toadfish (Opsanus tau) and scup (Stenotomus chrysops), and phylogenetic analysis of CYP1A genes. , 1995, The Biochemical journal.

[64]  R. Laslett Concentrations of dissolved and suspended particulate Cd, Cu, Mn, Ni, Pb and Zn in surface waters around the coasts of England and Wales and in adjacent seas , 1995 .

[65]  S. Safe,et al.  Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. , 1995, Pharmacology & therapeutics.

[66]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[67]  A. Yoshida,et al.  Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family. , 1994, Gene.

[68]  M. E. Hahn,et al.  Regulation of cytochrome P4501A1 in teleosts: sustained induction of CYP1A1 mRNA, protein, and catalytic activity by 2,3,7,8-tetrachlorodibenzofuran in the marine fish Stenotomus chrysops. , 1994, Toxicology and applied pharmacology.

[69]  T. T. Chen,et al.  Two unique CYP1 genes are expressed in response to 3-methylcholanthrene treatment in rainbow trout. , 1994, Archives of biochemistry and biophysics.

[70]  M. Leaver,et al.  Cytochrome P450 1A1 cDNA from plaice (Pleuronectes platessa) and induction of P450 1A1 mRNA in various tissues by 3-methylcholanthrene and isosafrole. , 1993, Molecular marine biology and biotechnology.

[71]  J. Stegeman,et al.  Elevated ornithine decarboxylase activity, polyamines and cell proliferation in neoplastic and vacuolated liver cells of winter flounder (Pleuronectes americanus) , 1993, Carcinogenesis.

[72]  E. Calabrese,et al.  Ornithine decarboxylase (ODC) activity in the liver of individual medaka (Oryzias latipes) of both sexes. , 1993, Ecotoxicology and environmental safety.

[73]  E. Myers,et al.  Basic local alignment search tool. , 1990, Journal of molecular biology.

[74]  Keith Dudley Short protocols in molecular biology , 1990 .

[75]  H. Weiner Aldehyde dehydrogenase. , 1982, Progress in clinical and biological research.