BRMS1L suppresses breast cancer metastasis by inducing epigenetic silence of FZD10

[1]  T. Smyrk,et al.  Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene. , 2014, American journal of physiology. Regulatory, integrative and comparative physiology.

[2]  J. Dannenberg,et al.  Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis , 2014, Haematologica.

[3]  Zhenyu Zhu,et al.  Effect of BRMS1 on Tumorigenicity and Metastasis of Human Rectal Cancer , 2014, Cell Biochemistry and Biophysics.

[4]  D. Welch,et al.  Breast cancer metastasis suppressor-1 promoter methylation in cell-free DNA provides prognostic information in non-small cell lung cancer , 2014, British Journal of Cancer.

[5]  C. Gong,et al.  MiR-106b expression determines the proliferation paradox of TGF-β in breast cancer cells , 2013, Oncogene.

[6]  P. Munster,et al.  Histone Deacetylase Regulation of ATM-Mediated DNA Damage Signaling , 2013, Molecular Cancer Therapeutics.

[7]  N. Negre,et al.  Sin3a acts through a multi-gene module to regulate invasion in Drosophila and human tumors , 2013, Oncogene.

[8]  Qi Zhang,et al.  Wnt/β-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling. , 2013, Carcinogenesis.

[9]  W. Birchmeier,et al.  Wnt signaling in stem and cancer stem cells. , 2013, Current opinion in cell biology.

[10]  Hongyun Wang,et al.  ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer. , 2013, The Journal of clinical investigation.

[11]  M. Mottolese,et al.  ATM kinase activity modulates ITCH E3-ubiquitin ligase activity , 2013, Oncogene.

[12]  Alykhan S. Nagji,et al.  BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300. , 2013, Cancer research.

[13]  Xun Zhu,et al.  MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasis. , 2013, The Journal of clinical investigation.

[14]  C. Plass,et al.  Genome-wide epigenetic regulation of miRNAs in cancer. , 2013, Cancer research.

[15]  P. Paul-Gilloteaux,et al.  ATAT1/MEC-17 acetyltransferase and HDAC6 deacetylase control a balance of acetylation of alpha-tubulin and cortactin and regulate MT1-MMP trafficking and breast tumor cell invasion. , 2012, European journal of cell biology.

[16]  Ying Sun,et al.  Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival , 2012, BMC Cancer.

[17]  M. Boutros,et al.  The Sin3a repressor complex is a master regulator of STAT transcriptional activity , 2012, Proceedings of the National Academy of Sciences.

[18]  M. Dawson,et al.  Cancer Epigenetics: From Mechanism to Therapy , 2012, Cell.

[19]  Hans Clevers,et al.  Wnt/β-Catenin Signaling and Disease , 2012, Cell.

[20]  Jungsuk An,et al.  Epithelial–mesenchymal transition in breast cancer correlates with high histological grade and triple‐negative phenotype , 2012, Histopathology.

[21]  H. Ford,et al.  The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer , 2012, Oncogene.

[22]  H. Friess,et al.  Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer , 2011, Gut.

[23]  D. Welch,et al.  Unraveling the enigmatic complexities of BRMS1‐mediated metastasis suppression , 2011, FEBS letters.

[24]  S. Fuqua,et al.  Resveratrol, through NF‐Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor α gene expression via p38MAPK/CK2 signaling in human breast cancer cells , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[25]  Xueli Bao,et al.  MiR-106b promotes cell proliferation via targeting RB in laryngeal carcinoma , 2011, Journal of experimental & clinical cancer research : CR.

[26]  M. Martinka,et al.  Prognostic significance of BRMS1 expression in human melanoma and its role in tumor angiogenesis , 2011, Oncogene.

[27]  J. Reis-Filho,et al.  β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation , 2011, Modern Pathology.

[28]  M. Loda,et al.  Identification of the miR-106b~25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation , 2010, Science Signaling.

[29]  Dongquan Chen,et al.  Breast cancer metastasis suppressor 1 coordinately regulates metastasis‐associated microRNA expression , 2009, International journal of cancer.

[30]  Marc Ladanyi,et al.  WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis , 2009, Cell.

[31]  C. Fan,et al.  A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer. , 2009, Cancer research.

[32]  Kedar S Vaidya,et al.  Over-expression of the BRMS1 family member SUDS3 does not suppress metastasis of human cancer cells. , 2009, Cancer letters.

[33]  Yusuke Nakamura,et al.  Inverse correlation of the up‐regulation of FZD10 expression and the activation of β‐catenin in synchronous colorectal tumors , 2009, Cancer science.

[34]  Yusuke Nakamura,et al.  Activation of the non-canonical Dvl–Rac1–JNK pathway by Frizzled homologue 10 in human synovial sarcoma , 2009, Oncogene.

[35]  Kedar S Vaidya,et al.  Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. , 2009, Cancer research.

[36]  G. Casey,et al.  BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-κB binding site of the uPA promoter , 2009, Clinical & Experimental Metastasis.

[37]  Kedar S Vaidya,et al.  Breast Cancer Metastasis Suppressor-1 Differentially Modulates Growth Factor Signaling* , 2008, Journal of Biological Chemistry.

[38]  Xiaoqi Liu,et al.  Breast cancer metastasis suppressor 1 inhibits SDF-1alpha-induced migration of non-small cell lung cancer by decreasing CXCR4 expression. , 2008, Cancer letters.

[39]  G. Casey,et al.  Downregulation of osteopontin contributes to metastasis suppression by breast cancer metastasis suppressor 1 , 2008, International journal of cancer.

[40]  Kedar S Vaidya,et al.  BRMS1 suppresses breast cancer metastasis in multiple experimental models of metastasis by reducing solitary cell survival and inhibiting growth initiation , 2008, Clinical & Experimental Metastasis.

[41]  Kedar S Vaidya,et al.  BRMS1 suppresses breast cancer experimental metastasis to multiple organs by inhibiting several steps of the metastatic process. , 2008, The American journal of pathology.

[42]  G. Casey,et al.  Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation , 2007, Molecular Cancer.

[43]  Yusuke Nakamura,et al.  Therapeutic potential of antibodies against FZD10, a cell-surface protein, for synovial sarcomas , 2005, Oncogene.

[44]  R. DePinho,et al.  mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival. , 2005, Genes & development.

[45]  J. Qin,et al.  Identification of a novel BRMS1-homologue protein p40 as a component of the mSin3A/p33(ING1b)/HDAC1 deacetylase complex. , 2004, Biochemical and biophysical research communications.

[46]  M. Katoh,et al.  Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT - beta-catenin - TCF signaling pathway. , 2002, International journal of molecular medicine.

[47]  K. Broman,et al.  Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1. , 2001, Cancer research.

[48]  H. Kirikoshi,et al.  Expression profiles of 10 members of Frizzled gene family in human gastric cancer. , 2001, International journal of oncology.

[49]  D. Welch,et al.  Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13. , 2000, Cancer research.

[50]  M. Hirai,et al.  Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family. , 1999, Biochemical and biophysical research communications.

[51]  L. Chin,et al.  Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression , 1997, nature.

[52]  H. Egami,et al.  Immunohistochemical expression of the c-kit proto-oncogene product in human malignant and non-malignant breast tissues. , 1996, British Journal of Cancer.

[53]  K. Friedrichs,et al.  Overexpression of p53 and prognosis in breast cancer , 1993, Cancer.

[54]  X. Zhi,et al.  Wnt/beta-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma by increasing hif-1alpha activity and decreasing hypoxia-associated cell death , 2012 .

[55]  A. Hart,et al.  Molecular markers of breast cancer metastasis , 2005 .