Application of empirical mode decomposition and artificial neural network for the classification of normal and epileptic EEG signals

Abstract Epilepsy is a neurological disorder affecting more than 50 million individuals in the world. Analysis of the electroencephalogram (EEG) is a powerful tool to assist neurologists for diagnosis and treatment. In this paper a new feature extraction method based on empirical mode decomposition (EMD) is proposed. The EEG signal is decomposed into intrinsic mode functions (IMFs) by the EMD algorithm and four statistical parameters are calculated over these IMFs constituting the input feature vector to be fed to a multilayer perceptron neural network (MLPNN) classifier. Experimental results carried out on the publicly available Bonn dataset show that an accurate classification rate of 100% is achieved in the discrimination between normal and ictal EEG, and an accuracy of 97.7% is reached in the classification of interictal and ictal EEG signals. Our results are equivalent or outperform recent studies published in the literature.

[1]  Hasan Ocak,et al.  Automatic detection of epileptic seizures in EEG using discrete wavelet transform and approximate entropy , 2009, Expert Syst. Appl..

[2]  C. Elger,et al.  Spatio-temporal dynamics of the primary epileptogenic area in temporal lobe epilepsy characterized by neuronal complexity loss. , 1995, Electroencephalography and clinical neurophysiology.

[3]  Abdulhamit Subasi,et al.  EEG signal classification using PCA, ICA, LDA and support vector machines , 2010, Expert Syst. Appl..

[4]  M. L. Dewal,et al.  Epileptic seizures detection in EEG using DWT-based ApEn and artificial neural network , 2012, Signal, Image and Video Processing.

[5]  Eric Laciar,et al.  An epileptic seizures detection algorithm based on the empirical mode decomposition of EEG , 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[6]  A. Liu,et al.  Detection of neonatal seizures through computerized EEG analysis. , 1992, Electroencephalography and clinical neurophysiology.

[7]  Rajeev Sharma,et al.  Classification of epileptic seizures in EEG signals based on phase space representation of intrinsic mode functions , 2015, Expert Syst. Appl..

[8]  Pradip Sircar,et al.  EEG signal analysis using FB expansion and second-order linear TVAR process , 2008, Signal Process..

[9]  Stephen M. Myers,et al.  Seizure prediction: Methods , 2011, Epilepsy & Behavior.

[10]  Ram Bilas Pachori,et al.  Epileptic seizure detection based on the instantaneous area of analytic intrinsic mode functions of EEG signals , 2013 .

[11]  V. Srinivasan,et al.  Approximate Entropy-Based Epileptic EEG Detection Using Artificial Neural Networks , 2007, IEEE Transactions on Information Technology in Biomedicine.

[12]  K Lehnertz,et al.  Indications of nonlinear deterministic and finite-dimensional structures in time series of brain electrical activity: dependence on recording region and brain state. , 2001, Physical review. E, Statistical, nonlinear, and soft matter physics.

[13]  U. Rajendra Acharya,et al.  Automated EEG analysis of epilepsy: A review , 2013, Knowl. Based Syst..

[14]  L. Tarassenko,et al.  Linear and non-linear methods for automatic seizure detection in scalp electro-encephalogram recordings , 2002, Medical and Biological Engineering and Computing.

[15]  Daniel Rivero,et al.  Epileptic seizure detection using multiwavelet transform based approximate entropy and artificial neural networks , 2010, Journal of Neuroscience Methods.

[16]  U. Rajendra Acharya,et al.  Application of Recurrence Quantification Analysis for the Automated Identification of Epileptic EEG Signals , 2011, Int. J. Neural Syst..

[17]  U. Rajendra Acharya,et al.  Entropies for detection of epilepsy in EEG , 2005, Comput. Methods Programs Biomed..

[18]  H. Adeli,et al.  Analysis of EEG records in an epileptic patient using wavelet transform , 2003, Journal of Neuroscience Methods.

[19]  Julius Georgiou,et al.  Detection of epileptic electroencephalogram based on Permutation Entropy and Support Vector Machines , 2012, Expert Syst. Appl..

[20]  N. Huang,et al.  The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis , 1998, Proceedings of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[21]  Gabriel Rilling,et al.  Empirical mode decomposition as a filter bank , 2004, IEEE Signal Processing Letters.

[22]  Kemal Polat,et al.  Classification of epileptiform EEG using a hybrid system based on decision tree classifier and fast Fourier transform , 2007, Appl. Math. Comput..

[23]  U. Rajendra Acharya,et al.  Automated identification of normal and diabetes heart rate signals using nonlinear measures , 2013, Comput. Biol. Medicine.

[24]  Rami J Oweis,et al.  Seizure classification in EEG signals utilizing Hilbert-Huang transform , 2011, Biomedical engineering online.

[25]  Shufang Li,et al.  Feature extraction and recognition of ictal EEG using EMD and SVM , 2013, Comput. Biol. Medicine.

[26]  Dimitrios I. Fotiadis,et al.  Automatic Seizure Detection Based on Time-Frequency Analysis and Artificial Neural Networks , 2007, Comput. Intell. Neurosci..

[27]  Elif Derya Übeyli Combined neural network model employing wavelet coefficients for EEG signals classification , 2009, Digit. Signal Process..

[28]  Guangyi Chen,et al.  Automatic EEG seizure detection using dual-tree complex wavelet-Fourier features , 2014, Expert Syst. Appl..

[29]  Priyanka,et al.  Genetic algorithms tuned expert model for detection of epileptic seizures from EEG signatures , 2014, Appl. Soft Comput..

[30]  Milos Borenovic,et al.  Space Partitioning Strategies for Indoor WLAN Positioning with Cascade-Connected ANN Structures , 2011, Int. J. Neural Syst..

[31]  Hong Lin,et al.  Identification of Spinal Deformity Classification with Total Curvature Analysis and Artificial Neural Network , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[32]  Ram Bilas Pachori,et al.  Classification of Seizure and Nonseizure EEG Signals Using Empirical Mode Decomposition , 2012, IEEE Transactions on Information Technology in Biomedicine.

[33]  Mahmut Ozer,et al.  EEG signals classification using the K-means clustering and a multilayer perceptron neural network model , 2011, Expert Syst. Appl..

[34]  M. L. Dewal,et al.  Epileptic seizure detection using DWT based fuzzy approximate entropy and support vector machine , 2014, Neurocomputing.

[35]  Wu Xiaopei,et al.  Motor imagery EEG detection by empirical mode decomposition , 2008, 2008 IEEE International Joint Conference on Neural Networks (IEEE World Congress on Computational Intelligence).

[36]  Elif Derya Übeyli,et al.  Recurrent neural networks employing Lyapunov exponents for EEG signals classification , 2005, Expert Syst. Appl..

[37]  P. Dario,et al.  Artificial neural network model of the mapping between electromyographic activation and trajectory patterns in free-arm movements , 2003, Medical and Biological Engineering and Computing.

[38]  Christopher M. Bishop,et al.  Neural networks for pattern recognition , 1995 .