Data driven filtering of bowel sounds using multivariate empirical mode decomposition

BackgroundThe analysis of abdominal sounds can help to diagnose gastro-intestinal diseases. Sounds originating from the stomach and the intestine, the so-called bowel sounds, occur in various forms. They are described as loose successions or clusters of rather sudden bursts. Realistic recordings of abdominal sounds are contaminated with noise and artifacts from which the bowel sounds must be differentiated.MethodsThe proposed intrinsic mode function-fractal dimension (IMF-FD) filtering utilizes the property of the multivariate empirical mode decomposition (MEMD) to behave as a series of band pass filters. The MEMD decomposes the abdominal signal into its different frequency components. The resulting intrinsic mode functions (IMFs) are modulated in amplitude and frequency where transient sonic events occur. Based on the complexity of the IMFs, measured by their fractal dimension (FD) in sliding windows, the information-carrying IMFs are selected. The filtered signal is formed as the superposition of all selected IMFs. The IMF-FD filter not only enhances the non-linear components of the original signal but also segments them from the rest. Another important aspect of this work is that typical artifacts that occur in the same frequency range as bowel sounds can be subsequently eliminated by heuristic rules.ConclusionsThe method is tested on a realistic, contaminated data set with promising performance: close to 100% of the manually labeled bowel sounds are identified.

[1]  G. Sturniolo,et al.  [Irritable bowel syndrome]. , 1988, Giornale di clinica medica.

[2]  Danilo P. Mandic,et al.  Filter Bank Property of Multivariate Empirical Mode Decomposition , 2011, IEEE Transactions on Signal Processing.

[3]  Didier Wolf,et al.  Digestive Activity Evaluation by Multichannel Abdominal Sounds Analysis , 2010, IEEE Transactions on Biomedical Engineering.

[4]  Richard H Sandler,et al.  Gastrointestinal sounds and migrating motor complex in fasted humans , 1999, American Journal of Gastroenterology.

[5]  R JoséKlinger,et al.  Irritable Bowel Syndrome , 2006 .

[6]  Morten Hovd,et al.  Detecting non-linearity induced oscillations via the dyadic filter bank property of multivariate empirical mode decomposition , 2017 .

[7]  Brian L. Craine,et al.  Enterotachogram Analysis to Distinguish Irritable Bowel Syndrome from Crohn's Disease , 2001, Digestive Diseases and Sciences.

[8]  Nicole McFarlane,et al.  Integrated real time bowel sound detector for artificial pancreas systems , 2016 .

[9]  G Devroede,et al.  Computer analysis of bowel sounds. , 1975, Computers in biology and medicine.

[10]  M. Pimentel,et al.  Psychological disorders in gastrointestinal disease: epiphenomenon, cause or consequence? , 2014, Annals of gastroenterology.

[11]  Charalampos Dimoulas,et al.  Pattern classification and audiovisual content management techniques using hybrid expert systems: A video-assisted bioacoustics application in Abdominal Sounds pattern analysis , 2011, Expert Syst. Appl..

[12]  H Ehrenreich,et al.  Non-invasive topographic analysis of intestinal activity in man on the basis of acustic phenomena , 1989, Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie.

[13]  N. Huang,et al.  The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis , 1998, Proceedings of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[14]  Umit D. Ulusar,et al.  Recovery of gastrointestinal tract motility detection using Naive Bayesian and minimum statistics , 2014, Comput. Biol. Medicine.

[15]  Wei Zheng,et al.  Foetal heart rate estimation by empirical mode decomposition and MUSIC spectrum , 2018, Biomed. Signal Process. Control..

[16]  D. Margel,et al.  Usefulness of bowel sound auscultation: a prospective evaluation. , 2014, Journal of surgical education.

[17]  Leontios J. Hadjileontiadis,et al.  Wavelet-based enhancement of lung and bowel sounds using fractal dimension thresholding-part I: methodology , 2005, IEEE Transactions on Biomedical Engineering.

[18]  Leontios J. Hadjileontiadis,et al.  Wavelet-based enhancement of lung and bowel sounds using fractal dimension thresholding-part II: application results , 2005, IEEE Transactions on Biomedical Engineering.

[19]  George Kalliris,et al.  Bowel-sound pattern analysis using wavelets and neural networks with application to long-term, unsupervised, gastrointestinal motility monitoring , 2008, Expert Syst. Appl..

[20]  H Yoshino,et al.  Clinical application of spectral analysis of bowel sounds in intestinal obstruction , 1990, Diseases of the colon and rectum.

[21]  D. Wolf,et al.  A COMPLETE TOOLBOX FOR ABDOMINAL SOUNDS SIGNAL PROCESSING AND ANALYSIS , 2005 .

[22]  Stavros M. Panas,et al.  Enhancement of bowel sounds by wavelet-based filtering , 2000, IEEE Transactions on Biomedical Engineering.

[23]  L.J. Hadjileontiadis,et al.  Detection of explosive lung and bowel sounds by means of fractal dimension , 2003, IEEE Signal Processing Letters.

[24]  Carlos Sevcik,et al.  A procedure to Estimate the Fractal Dimension of Waveforms , 2010, 1003.5266.