Combining Gal4p-mediated expression enhancement and directed evolution of isoprene synthase to improve isoprene production in Saccharomyces cerevisiae.
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Xiaomei Lv | Chengcheng Yang | Zhen Yao | Hongwei Yu | Hongwei Yu | Wenping Xie | Lidan Ye | Fan Wang | Pingping Zhou | Yongqiang Zhu | Xiaohong Yang | Xiaomei Lv | Fan Wang | Wenping Xie | Lidan Ye | Yongqiang Zhu | Zhen Yao | Xiaohong Yang | Chengcheng Yang | Pingping Zhou
[1] Jiali Gu,et al. Enhanced isoprene biosynthesis in Saccharomyces cerevisiae by engineering of the native acetyl-CoA and mevalonic acid pathways with a push-pull-restrain strategy. , 2014, Journal of biotechnology.
[2] Xiaomei Lv,et al. Sequential control of biosynthetic pathways for balanced utilization of metabolic intermediates in Saccharomyces cerevisiae. , 2015, Metabolic engineering.
[3] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[4] J. Keasling,et al. Engineering a mevalonate pathway in Escherichia coli for production of terpenoids , 2003, Nature Biotechnology.
[5] Haoming Xu,et al. Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae , 2016, Nature Communications.
[6] Jens Nielsen,et al. Increasing galactose consumption by Saccharomyces cerevisiae through metabolic engineering of the GAL gene regulatory network , 2000, Nature Biotechnology.
[7] Mo Xian,et al. Biosynthesis of isoprene in Escherichia coli via methylerythritol phosphate (MEP) pathway , 2011, Applied Microbiology and Biotechnology.
[8] Min-Kyu Oh,et al. A synthetic suicide riboswitch for the high-throughput screening of metabolite production in Saccharomyces cerevisiae. , 2015, Metabolic engineering.
[9] Thomas Fiedler,et al. A new efficient gene disruption cassette for repeated use in budding yeast , 1996, Nucleic Acids Res..
[10] A. Melis,et al. Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism. , 2010, Metabolic engineering.
[11] D. Lohr,et al. Transcriptional regulation in the yeast GAL gene family: a complex genetic network , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[12] A. Melis,et al. Heterologous expression of the mevalonic acid pathway in cyanobacteria enhances endogenous carbon partitioning to isoprene. , 2014, Molecular plant.
[13] Xianpu Ni,et al. Assembly of a novel biosynthetic pathway for gentamicin B production in Micromonospora echinospora , 2016, Microbial Cell Factories.
[14] R. D. Gietz,et al. Yeast transformation by the LiAc/SS carrier DNA/PEG method. , 2014, Methods in molecular biology.
[15] Hal S Alper,et al. Characterization of plasmid burden and copy number in Saccharomyces cerevisiae for optimization of metabolic engineering applications. , 2013, FEMS yeast research.
[16] U. Stahl,et al. Overexpression of a cytosolic hydroxymethylglutaryl-CoA reductase leads to squalene accumulation in yeast , 1998, Applied Microbiology and Biotechnology.
[17] Koichi Abe,et al. Development of a light-regulated cell-recovery system for non-photosynthetic bacteria , 2016, Microbial Cell Factories.
[18] M. Johnston,et al. Multiple mechanisms provide rapid and stringent glucose repression of GAL gene expression in Saccharomyces cerevisiae , 1994, Molecular and cellular biology.
[19] F. Arnold,et al. Directed evolution of enzyme catalysts. , 1997, Trends in biotechnology.
[20] R. Komel,et al. A novel GAL recombinant yeast strain for enhanced protein production. , 2006, Biomolecular engineering.
[21] D. Christianson,et al. Structure of isoprene synthase illuminates the chemical mechanism of teragram atmospheric carbon emission. , 2010, Journal of molecular biology.
[22] M Ptashne,et al. Cooperative DNA binding of the yeast transcriptional activator GAL4. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[23] D. Christianson,et al. Probing the mechanism of 1,4-conjugate elimination reactions catalyzed by terpene synthases. , 2012, Journal of the American Chemical Society.
[24] Jay D Keasling,et al. Production of isoprenoid pharmaceuticals by engineered microbes , 2006, Nature chemical biology.
[25] A. Melis,et al. Isoprene Production Via the Mevalonic Acid Pathway in Escherichia coli (Bacteria) , 2012, BioEnergy Research.
[26] Jiali Gu,et al. Construction of a controllable β‐carotene biosynthetic pathway by decentralized assembly strategy in Saccharomyces cerevisiae , 2014, Biotechnology and bioengineering.
[27] Jens Nielsen,et al. Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries , 2012, Cellular and Molecular Life Sciences.
[28] J. Hopper,et al. Disruption of regulatory gene GAL80 in Saccharomyces cerevisiae: effects on carbon-controlled regulation of the galactose/melibiose pathway genes , 1984, Molecular and cellular biology.
[29] Junfeng Xue,et al. Enhancing Isoprene Production by Genetic Modification of the 1-Deoxy-d-Xylulose-5-Phosphate Pathway in Bacillus subtilis , 2011, Applied and Environmental Microbiology.
[30] Jiali Gu,et al. Combinatorial pathway optimization in Escherichia coli by directed co‐evolution of rate‐limiting enzymes and modular pathway engineering , 2016, Biotechnology and bioengineering.
[31] S. Johnston,et al. Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[32] Hongwei Yu,et al. Engineering microbes for isoprene production. , 2016, Metabolic engineering.
[33] E. Sakuradani,et al. Overexpression of the gene encoding HMG-CoA reductase in Saccharomyces cerevisiae for production of prenyl alcohols , 2009, Applied Microbiology and Biotechnology.
[34] P. Palmer,et al. Estimates of global terrestrial isoprene emissions using MEGAN (Model of Emissions of Gases and Aerosols from Nature) , 2006 .
[35] Jay D. Keasling,et al. Identification of Isopentenol Biosynthetic Genes from Bacillus subtilis by a Screening Method Based on Isoprenoid Precursor Toxicity , 2007, Applied and Environmental Microbiology.
[36] Li Zhou,et al. Development of an efficient autoinducible expression system by promoter engineering in Bacillus subtilis , 2016, Microbial Cell Factories.
[37] Mark Ptashne,et al. Negative effect of the transcriptional activator GAL4 , 1988, Nature.
[38] J. Keasling. Synthetic biology and the development of tools for metabolic engineering. , 2012, Metabolic engineering.
[39] T. Sharkey,et al. ISOPRENE SYNTHASE GENES FORM A MONOPHYLETIC CLADE OF ACYCLIC TERPENE SYNTHASES IN THE TPS‐B TERPENE SYNTHASE FAMILY , 2013, Evolution; international journal of organic evolution.
[40] J. Boeke,et al. Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR‐mediated gene disruption and other applications , 1998, Yeast.
[41] D. Porro,et al. Alteration of cell population structure due to cell lysis in Saccharomyces cerevisiae cells overexpressing the GAL4 gene , 1993, Yeast.
[42] Sang Woo Seo,et al. Synthetic biology: tools to design microbes for the production of chemicals and fuels. , 2013, Biotechnology advances.
[43] J. Pronk,et al. Fermentative capacity in high‐cell‐density fed‐batch cultures of baker's yeast , 2000, Biotechnology and bioengineering.
[44] Kanako Sasaki,et al. Gene expression and characterization of isoprene synthase from Populus alba , 2005, FEBS letters.
[45] Bingbing Sun,et al. Synergy between methylerythritol phosphate pathway and mevalonate pathway for isoprene production in Escherichia coli. , 2016, Metabolic engineering.
[46] Haoming Xu,et al. Significantly enhanced production of isoprene by ordered coexpression of genes dxs, dxr, and idi in Escherichia coli , 2012, Applied Microbiology and Biotechnology.
[47] Jiali Gu,et al. Enhanced production of coenzyme Q10 by self‐regulating the engineered MEP pathway in Rhodobacter sphaeroides , 2014, Biotechnology and bioengineering.