Glutamate-releasing BEST1 channel is a new target for neuroprotection against ischemic stroke with wide time window
暂无分享,去创建一个
Lei Chang | Dongya Zhu | Li-Yan Gao | Haiyin Wu | C. Luo | M. Sun | Hui Xiao | Hai‐Ying Liang | Ke Xu | Yunjie Liu | Yuhui Lin | Shuai Xiong | Nan Jiang | Chunxia Luo
[1] Jingliang Zhang,et al. Inhibition of intracellular proton-sensitive Ca2+-permeable TRPV3 channels protects against ischemic brain injury , 2022, Acta pharmaceutica Sinica. B.
[2] M. De Vivo,et al. Pharmacological tools to target NKCC1 in brain disorders. , 2021, Trends in pharmacological sciences.
[3] J. Ji,et al. Sphingosine-1-phosphate, a novel TREM2 ligand, promotes microglial phagocytosis to protect against ischemic brain injury , 2021, Acta pharmaceutica Sinica. B.
[4] Wendong Xu,et al. Smoothened is a therapeutic target for reducing glutamate toxicity in ischemic stroke , 2021, Science Translational Medicine.
[5] Fei Li,et al. A pain killer without analgesic tolerance designed by co-targeting PSD-95-nNOS interaction and α2-containning GABAARs , 2021, Theranostics.
[6] Xin-Fu Zhou. ESCAPE-NA1 Trial Brings Hope of Neuroprotective Drugs for Acute Ischemic Stroke: Highlights of the Phase 3 Clinical Trial on Nerinetide , 2021, Neuroscience Bulletin.
[7] Lei Chang,et al. Environmental enrichment implies GAT-1 as a potential therapeutic target for stroke recovery , 2021, Theranostics.
[8] So Yeong Lee,et al. High Salt Intake Recruits Tonic Activation of NR2D Subunit-Containing Extrasynaptic NMDARs in Vasopressin Neurons , 2020, The Journal of Neuroscience.
[9] Li-fang Liu,et al. Orthogonal label and label-free dual pretreatment for targeted profiling of neurotransmitters in enteric nervous system. , 2020, Analytica chimica acta.
[10] Hyung-Seok Kim,et al. Excessive Astrocytic GABA Causes Cortical Hypometabolism and Impedes Functional Recovery after Subcortical Stroke. , 2020, Cell reports.
[11] Lei Chang,et al. nNOS-expressing neurons in the vmPFC transform pPVT-derived chronic pain signals into anxiety behaviors , 2020, Nature Communications.
[12] Thalia Shoshana Field,et al. Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial. , 2020, The Lancet.
[13] Dong Woon Kim,et al. Bestrophin1‐mediated tonic GABA release from reactive astrocytes prevents the development of seizure‐prone network in kainate‐injected hippocampi , 2019, Glia.
[14] Zhiping Hu,et al. Potential Neuroprotective Treatment of Stroke: Targeting Excitotoxicity, Oxidative Stress, and Inflammation , 2019, Front. Neurosci..
[15] Junhua Yang,et al. Glutamate-Releasing SWELL1 Channel in Astrocytes Modulates Synaptic Transmission and Promotes Brain Damage in Stroke , 2019, Neuron.
[16] H. Park,et al. Control of motor coordination by astrocytic tonic GABA release through modulation of excitation/inhibition balance in cerebellum , 2018, Proceedings of the National Academy of Sciences.
[17] W. Powers,et al. 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association , 2018, Stroke.
[18] Lei Chang,et al. Dissociation of nNOS from PSD‐95 promotes functional recovery after cerebral ischaemia in mice through reducing excessive tonic GABA release from reactive astrocytes , 2018, The Journal of pathology.
[19] Lei Chang,et al. Opening a New Time Window for Treatment of Stroke by Targeting HDAC2 , 2017, The Journal of Neuroscience.
[20] S. Oh,et al. Distribution and Function of the Bestrophin-1 (Best1) Channel in the Brain , 2017, Experimental neurobiology.
[21] John H. Zhang,et al. Phase I and Phase II Therapies for Acute Ischemic Stroke: An Update on Currently Studied Drugs in Clinical Research , 2017, BioMed research international.
[22] M. Darlison,et al. Chloride co‐transporters as possible therapeutic targets for stroke , 2017, Journal of neurochemistry.
[23] K. Kunzelmann. TMEM16, LRRC8A, bestrophin: chloride channels controlled by Ca(2+) and cell volume. , 2015, Trends in biochemical sciences.
[24] Dongyang Huang,et al. Characterization of the effects of Cl− channel modulators on TMEM16A and bestrophin-1 Ca2+ activated Cl− channels , 2015, Pflügers Archiv - European Journal of Physiology.
[25] S. Long,et al. Structure and insights into the function of a Ca2+-activated Cl− channel , 2014, Nature.
[26] Fengyun Zhang,et al. Interaction of nNOS with PSD-95 Negatively Controls Regenerative Repair after Stroke , 2014, The Journal of Neuroscience.
[27] J. A. Payne,et al. Cation-chloride cotransporters in neuronal development, plasticity and disease , 2014, Nature Reviews Neuroscience.
[28] K. Kikuchi,et al. Clinical Trials in Acute Ischemic Stroke , 2014, CNS Drugs.
[29] Federico N. Soria,et al. Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damage. , 2014, The Journal of clinical investigation.
[30] Yong Jeong,et al. GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease , 2014, Nature Medicine.
[31] Y. T. Wang,et al. Excitotoxicity and stroke: Identifying novel targets for neuroprotection , 2014, Progress in Neurobiology.
[32] P. Ortinski,et al. Extrasynaptic Targeting of NMDA Receptors Following D1 Dopamine Receptor Activation and Cocaine Self-Administration , 2013, The Journal of Neuroscience.
[33] Y. Bae,et al. TREK-1 and Best1 Channels Mediate Fast and Slow Glutamate Release in Astrocytes upon GPCR Activation , 2012, Cell.
[34] Mark Ellisman,et al. DIDS Prevents Ischemic Membrane Degradation in Cultured Hippocampal Neurons by Inhibiting Matrix Metalloproteinase Release , 2012, PloS one.
[35] Fan Wang,et al. The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons , 2012, Nature Neuroscience.
[36] Y. Jan,et al. Calcium-Activated Chloride Channels (CaCCs) Regulate Action Potential and Synaptic Response in Hippocampal Neurons , 2012, Neuron.
[37] F. Scamps,et al. Calcium-activated chloride current expression in axotomized sensory neurons: what for? , 2012, Front. Mol. Neurosci..
[38] W. Lu,et al. Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95 , 2010, Nature Medicine.
[39] Hee-Sup Shin,et al. Channel-Mediated Tonic GABA Release from Glia , 2010, Science.
[40] Eng H. Lo,et al. The Science of Stroke: Mechanisms in Search of Treatments , 2010, Neuron.
[41] C. Roncero,et al. Transient focal cerebral ischemia significantly alters not only EAATs but also VGLUTs expression in rats: relevance of changes in reactive astroglia , 2010, Journal of neurochemistry.
[42] S. Traynelis,et al. Bestrophin-1 Encodes for the Ca2+-Activated Anion Channel in Hippocampal Astrocytes , 2009, The Journal of Neuroscience.
[43] A. Marmorstein,et al. Best1 Is a Gene Regulated by Nerve Injury and Required for Ca2+-Activated Cl− Current Expression in Axotomized Sensory Neurons , 2009, The Journal of Neuroscience.
[44] Claudio Rivera,et al. Cation-Chloride Cotransporters and Neuronal Function , 2009, Neuron.
[45] G. Haddad,et al. DIDS protects against neuronal injury by blocking Toll‐like receptor 2 activated‐mechanisms , 2009, Journal of neurochemistry.
[46] A. Villringer,et al. The β-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke , 2008, Journal of hypertension.
[47] M. Gobbi,et al. Neuroprotective Effects of the Novel Glutamate Transporter Inhibitor (–)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]-isoxazole-4-carboxylic Acid, Which Preferentially Inhibits Reverse Transport (Glutamate Release) Compared with Glutamate Reuptake , 2008, Journal of Pharmacology and Experimental Therapeutics.
[48] E. Lo,et al. A new penumbra: transitioning from injury into repair after stroke , 2008, Nature Medicine.
[49] H. C. Hartzell,et al. Molecular physiology of bestrophins: multifunctional membrane proteins linked to best disease and other retinopathies. , 2008, Physiological reviews.
[50] G. Haddad,et al. Cell death in an ischemic infarct rim model , 2007, Journal of neurochemistry.
[51] S. Shioda,et al. Anion channel blockers attenuate delayed neuronal cell death induced by transient forebrain ischemia , 2007, Journal of neuroscience research.
[52] H. C. Hartzell,et al. The Anion-Selective Pore of the Bestrophins, a Family of Chloride Channels Associated with Retinal Degeneration , 2006, The Journal of Neuroscience.
[53] Roger J. Thompson,et al. Ischemia Opens Neuronal Gap Junction Hemichannels , 2006, Science.
[54] Tian-Le Xu,et al. Coupling between NMDA Receptor and Acid-Sensing Ion Channel Contributes to Ischemic Neuronal Death , 2005, Neuron.
[55] D. Attwell,et al. Tonic release of glutamate by a DIDS‐sensitive mechanism in rat hippocampal slices , 2005, The Journal of physiology.
[56] P. Fisher,et al. β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression , 2005, Nature.
[57] I. Ford,et al. Magnesium for acute stroke (Intravenous Magnesium Efficacy in Stroke trial): randomised controlled trial , 2004, The Lancet.
[58] P. Stys,et al. Aberrant Chloride Transport Contributes to Anoxic/Ischemic White Matter Injury , 2003, The Journal of Neuroscience.
[59] J. Rothstein,et al. Antisense Knockdown of the Glial Glutamate Transporter GLT-1, But Not the Neuronal Glutamate Transporter EAAC1, Exacerbates Transient Focal Cerebral Ischemia-Induced Neuronal Damage in Rat Brain , 2001, The Journal of Neuroscience.
[60] K. Lees,et al. Phase II Clinical Trial of Sipatrigine (619C89) by Continuous Infusion in Acute Stroke , 2000, Cerebrovascular Diseases.
[61] J. Phillis,et al. Transporter reversal as a mechanism of glutamate release from the ischemic rat cerebral cortex: studies with dl-threo-β-benzyloxyaspartate , 2000, Brain Research.
[62] D. Attwell,et al. Glutamate release in severe brain ischaemia is mainly by reversed uptake , 2000, Nature.
[63] M. Metzker,et al. Identification of the gene responsible for Best macular dystrophy , 1998, Nature Genetics.
[64] M. Hediger,et al. Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate , 1996, Neuron.
[65] D. Attwell,et al. Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms , 1994, Trends in Neurosciences.
[66] K. Valentino,et al. A selective N-type calcium channel antagonist protects against neuronal loss after global cerebral ischemia. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[67] J. Rothstein,et al. Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[68] H. Benveniste,et al. Cellular Origin of Ischemia‐Induced Glutamate Release from Brain Tissue In Vivo and In Vitro , 1985, Journal of neurochemistry.
[69] G. Feng,et al. The Chloride Transporter Na+-K+-Cl− Cotransporter Isoform-1 Contributes to Intracellular Chloride Increases after In Vitro Ischemia , 2006, The Journal of Neuroscience.