Is telomerase a novel target for metastatic colon cancer?
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[1] J. Shay,et al. Pancreatic cancer stem cells: fact or fiction? , 2009, Biochimica et biophysica acta.
[2] J. Shay,et al. Prostate tumor-initiating cells: a new target for telomerase inhibition therapy? , 2009, Biochimica et biophysica acta.
[3] J. Shay,et al. Targeting telomerase for cancer therapeutics , 2008, British Journal of Cancer.
[4] Y. Ho,et al. Real‐time PCR quantification of human telomerase reverse transcriptase (hTERT) in colorectal cancer , 2008, Pathology.
[5] C. Harley,et al. Oligonucleotide Conjugate GRN163L Targeting Human Telomerase as Potential Anticancer and Antimetastatic Agent , 2007, Nucleosides, nucleotides & nucleic acids.
[6] J. Shay,et al. Human diseases of telomerase dysfunction: insights into tissue aging , 2007, Nucleic acids research.
[7] L. Emens,et al. GV-1001, an injectable telomerase peptide vaccine for the treatment of solid cancers. , 2007, Current opinion in molecular therapeutics.
[8] R. Vonderheide. Universal tumor antigens for cancer vaccination: targeting telomerase for immunoprevention. , 2007, Discovery medicine.
[9] Chao Xing,et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase , 2007, Proceedings of the National Academy of Sciences.
[10] K. Brown,et al. Chemoselective Deprotection of α-Indole and Imidazole Ribonucleosides , 2007 .
[11] J. Shay,et al. Telomerase therapeutics for cancer: challenges and new directions , 2006, Nature Reviews Drug Discovery.
[12] J. Shay,et al. 4 Telomerase and Human Cancer , 2006 .
[13] T. Lange,et al. Shelterin: the protein complex that shapes and safeguards human telomeres , 2005 .
[14] J. Shay,et al. Telomerase as a therapeutic target in cancer , 2005 .
[15] C. Greider,et al. Telomerase and cancer stem cells. , 2005, Cold Spring Harbor symposia on quantitative biology.
[16] Axel Hoos,et al. Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[17] J. Shay. Telomerase therapeutics: telomeres recognized as a DNA damage signal: commentary re: K. Kraemer et al., antisense-mediated hTERT inhibition specifically reduces the growth of human bladder cancer cells. Clin. Cancer Res., 9: 3794-3800, 2003. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[18] J. Shay,et al. Telomerase: a target for cancer therapeutics. , 2002, Cancer cell.
[19] J. Shay,et al. Historical claims and current interpretations of replicative aging , 2002, Nature Biotechnology.
[20] J. Shay,et al. Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues. , 2001, Neoplasia.
[21] J. Shay,et al. High telomerase activity is an independent prognostic indicator of poor outcome in colorectal cancer. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[22] J. Griffith,et al. Mammalian Telomeres End in a Large Duplex Loop , 1999, Cell.
[23] M. Bibby. Telomeres and Telomerase. Ciba Foundation Symposium 211 , 1999, British Journal of Cancer.
[24] J. Shay,et al. Telomerase in cancer: diagnostic, prognostic, and therapeutic implications. , 1998, The cancer journal from Scientific American.
[25] C. Harley,et al. Extension of life-span by introduction of telomerase into normal human cells. , 1998, Science.
[26] J. Guillem,et al. Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer. , 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.
[27] C B Harley,et al. Telomerase catalytic subunit homologs from fission yeast and human. , 1997, Science.
[28] J. Shay,et al. A survey of telomerase activity in human cancer. , 1997, European journal of cancer.
[29] A. Gazdar,et al. Telomerase in the early detection of cancer. , 1997, Journal of clinical pathology.
[30] J. Shay,et al. Telomerase assays in the diagnosis and prognosis of cancer. , 1997, Ciba Foundation symposium.
[31] B. Warren,et al. Detection of telomerase activity in exfoliated cancer cells in colonic luminal washings and its related clinical implications. , 1997, British Journal of Cancer.
[32] J. Shay,et al. Telomerase activity in human intestine. , 1996, International journal of oncology.
[33] J. Shay,et al. Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. , 1996, Cancer research.
[34] J. Shay,et al. Telomerase activity in human germline and embryonic tissues and cells. , 1996, Developmental genetics.
[35] J. Shay,et al. Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions. , 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.
[36] et al.,et al. The RNA component of human telomerase , 1995, Science.
[37] S. Gallinger,et al. Telomerase activity associated with acquisition of malignancy in human colorectal cancer. , 1995, Cancer research.
[38] E. Hiyama,et al. Alteration of telomeric repeat length in adult and childhood solid neoplasias. , 1995, International journal of oncology.
[39] C B Harley,et al. Specific association of human telomerase activity with immortal cells and cancer. , 1994, Science.
[40] H. Cooke,et al. In vivo loss of telomeric repeats with age in humans. , 1991, Mutation research.
[41] Robin C. Allshire,et al. Telomere reduction in human colorectal carcinoma and with ageing , 1990, Nature.
[42] C. Harley,et al. Telomeres shorten during ageing of human fibroblasts , 1990, Nature.
[43] R. Myers,et al. Structure and variability of human chromosome ends , 1990, Molecular and cellular biology.
[44] L. S. Cram,et al. A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[45] H. Cooke,et al. Variability at the telomeres of the human X/Y pseudoautosomal region. , 1986, Cold Spring Harbor symposia on quantitative biology.
[46] Carol W. Greider,et al. Identification of a specific telomere terminal transferase activity in tetrahymena extracts , 1985, Cell.
[47] E. Blackburn,et al. A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena. , 1978, Journal of molecular biology.
[48] J. D. Watson. Origin of Concatemeric T7DNA , 1972 .
[49] J. Yudkin. Sugar and Disease , 1972, Nature.
[50] B. Mcclintock. Cytological observations of deficiencies involving known genes, translocations and an inversion in Zea mays , 1931 .