论文信息 - Triple-Modality Normalized Mutual Information Based Medical Image Registration of Cardiac PET/CT and SPECT Images

Triple-Modality Normalized Mutual Information Based Medical Image Registration of Cardiac PET/CT and SPECT Images

An extension of the normalized mutual information similarity measurement was proposed to register cardiac PET/CT and SPECT images representing coronary artery disease in the heart. 23 PET/CT images obtained by a hybrid camera, and their corresponding SPECT were processed. The SPECT was registered to the PET/CT image pairs by a triple NMI based auto-registration. For validation and comparison an triple MI based registration among the PET-SPECT-CT images was performed. Two further dual NMI based auto-registrations between the SPECT-CT and SPECT-PET were performed as well. Based on the comparative results gained by a medical expert, our triple NMI method gave the best transformation parameters with a minimal number of iterations to superimpose the images.

Reinhard Koch | Laszlo Papp | Maaz Zuhayra

[1] M. Zanca,et al. A comparative study of Powell's and Downhill Simplex algorithms for a fast multimodal surface matching in brain imaging. , 2001, Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

[2] Lennart Thurfjell,et al. A multivariate approach to registration of dissimilar tomographic images , 1999, European Journal of Nuclear Medicine.

[3] Charles R. Meyer,et al. Multi-variate Mutual Information for Registration , 1999, MICCAI.

[4] Joachim Hornegger,et al. Registration of Cardiac SPECT/CT Data Through Weighted Intensity Co-occurrence Priors , 2007, MICCAI.

[5] Max A. Viergever,et al. Mutual-information-based registration of medical images: a survey , 2003, IEEE Transactions on Medical Imaging.

[6] Colin Studholme,et al. An overlap invariant entropy measure of 3D medical image alignment , 1999, Pattern Recognit..