How antibiotics kill bacteria: from targets to networks
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[1] Xilin Zhao,et al. Contribution of reactive oxygen species to pathways of quinolone-mediated bacterial cell death. , 2010, The Journal of antimicrobial chemotherapy.
[2] M. DePristo,et al. Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. , 2010, Molecular cell.
[3] G. Walker,et al. Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. , 2009, Molecular cell.
[4] R. Kishony,et al. Nonoptimal Microbial Response to Antibiotics Underlies Suppressive Drug Interactions , 2009, Cell.
[5] J. Collins,et al. Role of reactive oxygen species in antibiotic action and resistance. , 2009, Current opinion in microbiology.
[6] S. Singleton,et al. Inhibitors of RecA Activity Discovered by High-Throughput Screening: Cell-Permeable Small Molecules Attenuate the SOS Response in Escherichia coli , 2009, Journal of biomolecular screening.
[7] E. Nudler,et al. Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics , 2009, Science.
[8] T. Bernhardt,et al. LytM-Domain Factors Are Required for Daughter Cell Separation and Rapid Ampicillin-Induced Lysis in Escherichia coli , 2009, Journal of bacteriology.
[9] Roy Kishony,et al. Drug interactions and the evolution of antibiotic resistance , 2009, Nature Reviews Microbiology.
[10] G. Cambray,et al. The SOS Response Controls Integron Recombination , 2009, Science.
[11] Timothy K Lu,et al. Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy , 2009, Proceedings of the National Academy of Sciences.
[12] Adam M. Feist,et al. Reconstruction of biochemical networks in microorganisms , 2009, Nature Reviews Microbiology.
[13] D. Dwyer,et al. Networking Opportunities for Bacteria , 2008, Cell.
[14] Ilana Kolodkin-Gal,et al. The Communication Factor EDF and the Toxin–Antitoxin Module mazEF Determine the Mode of Action of Antibiotics , 2008, PLoS biology.
[15] J. Collins,et al. Mistranslation of Membrane Proteins and Two-Component System Activation Trigger Antibiotic-Mediated Cell Death , 2008, Cell.
[16] R. Hancock,et al. Novel Genetic Determinants of Low-Level Aminoglycoside Resistance in Pseudomonas aeruginosa , 2008, Antimicrobial Agents and Chemotherapy.
[17] Robert E. W. Hancock,et al. Complex Ciprofloxacin Resistome Revealed by Screening a Pseudomonas aeruginosa Mutant Library for Altered Susceptibility , 2008, Antimicrobial Agents and Chemotherapy.
[18] Zaida Luthey-Schulten,et al. Molecular signatures of ribosomal evolution , 2008, Proceedings of the National Academy of Sciences.
[19] Gary Taubes,et al. The Bacteria Fight Back , 2008, Science.
[20] Jeffrey H. Miller,et al. Determination of Antibiotic Hypersensitivity among 4,000 Single-Gene-Knockout Mutants of Escherichia coli , 2008, Journal of bacteriology.
[21] James T. Park,et al. How Bacteria Consume Their Own Exoskeletons (Turnover and Recycling of Cell Wall Peptidoglycan) , 2008, Microbiology and Molecular Biology Reviews.
[22] Amy K. Schmid,et al. A Predictive Model for Transcriptional Control of Physiology in a Free Living Cell , 2007, Cell.
[23] R. Jayaswal,et al. Transcriptional Profiling Reveals that Daptomycin Induces the Staphylococcus aureus Cell Wall Stress Stimulon and Genes Responsive to Membrane Depolarization , 2007, Antimicrobial Agents and Chemotherapy.
[24] J. Collins,et al. A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics , 2007, Cell.
[25] K. Bayles. The biological role of death and lysis in biofilm development , 2007, Nature Reviews Microbiology.
[26] Xilin Zhao,et al. Quinolone-Mediated Bacterial Death , 2007, Antimicrobial Agents and Chemotherapy.
[27] James J. Collins,et al. Dispersing biofilms with engineered enzymatic bacteriophage , 2007, Proceedings of the National Academy of Sciences.
[28] J. Collins,et al. Large-Scale Mapping and Validation of Escherichia coli Transcriptional Regulation from a Compendium of Expression Profiles , 2007, PLoS biology.
[29] R. Hancock,et al. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies , 2006, Nature Biotechnology.
[30] J. Vila. Faculty Opinions recommendation of Inhibition of mutation and combating the evolution of antibiotic resistance. , 2006 .
[31] R. Kishony,et al. Functional classification of drugs by properties of their pairwise interactions , 2006, Nature Genetics.
[32] Michelle D. Brazas,et al. Using microarray gene signatures to elucidate mechanisms of antibiotic action and resistance. , 2005, Drug discovery today.
[33] J. Beckwith,et al. Diverse Paths to Midcell: Assembly of the Bacterial Cell Division Machinery , 2005, Current Biology.
[34] T. Silhavy,et al. Sensing external stress: watchdogs of the Escherichia coli cell envelope. , 2005, Current opinion in microbiology.
[35] C. Walsh,et al. Glycopeptide and lipoglycopeptide antibiotics. , 2005, Chemical reviews.
[36] H. Floss,et al. Rifamycin-mode of action, resistance, and biosynthesis. , 2005, Chemical reviews.
[37] G. Ashley,et al. Translation and protein synthesis: macrolides. , 2005, Chemical reviews.
[38] T. Mukhtar,et al. Streptogramins, oxazolidinones, and other inhibitors of bacterial protein synthesis. , 2005, Chemical reviews.
[39] K. Young,et al. FtsZ Collaborates with Penicillin Binding Proteins To Generate Bacterial Cell Shape in Escherichia coli , 2004, Journal of bacteriology.
[40] T. Raivio. Faculty Opinions recommendation of SOS response induction by beta-lactams and bacterial defense against antibiotic lethality. , 2004 .
[41] Stanley N Cohen,et al. SOS Response Induction by ß-Lactams and Bacterial Defense Against Antibiotic Lethality , 2004, Science.
[42] D. Georgellis,et al. Identification of a quinone-sensitive redox switch in the ArcB sensor kinase. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[43] R. Pratt,et al. The perfect penicillin? Inhibition of a bacterial DD-peptidase by peptidoglycan-mimetic beta-lactams. , 2004, Journal of the American Chemical Society.
[44] O. Espéli,et al. Untangling intracellular DNA topology , 2004, Molecular microbiology.
[45] Xueqiao Liu,et al. Probing the ArcA-P Modulon of Escherichia coli by Whole Genome Transcriptional Analysis and Sequence Recognition Profiling* , 2004, Journal of Biological Chemistry.
[46] J. Imlay,et al. Pathways of oxidative damage. , 2003, Annual review of microbiology.
[47] J. Courcelle,et al. RecA-dependent recovery of arrested DNA replication forks. , 2003, Annual review of genetics.
[48] Clement S. Chu,et al. A New Class of Bacterial RNA Polymerase Inhibitor Affects Nucleotide Addition , 2003, Science.
[49] Måns Ehrenberg,et al. The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. , 2003, Journal of molecular biology.
[50] J. Collins,et al. Inferring Genetic Networks and Identifying Compound Mode of Action via Expression Profiling , 2003, Science.
[51] S. Mobashery,et al. Versatility of Aminoglycosides and Prospects for Their Future , 2003, Clinical Microbiology Reviews.
[52] B. Firek,et al. The Staphylococcus aureus cidAB Operon: Evaluation of Its Role in Regulation of Murein Hydrolase Activity and Penicillin Tolerance , 2003, Journal of bacteriology.
[53] C. Walsh. Antibiotics: Actions, Origins, Resistance , 2003 .
[54] H. Schwarz,et al. Effects of Multiple Deletions of Murein Hydrolases on Viability, Septum Cleavage, and Sensitivity to Large Toxic Molecules in Escherichia coli , 2002, Journal of bacteriology.
[55] U. Alon,et al. Assigning numbers to the arrows: Parameterizing a gene regulation network by using accurate expression kinetics , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[56] J. Heddle,et al. Quinolone-Binding Pocket of DNA Gyrase: Role of GyrB , 2002, Antimicrobial Agents and Chemotherapy.
[57] F. Hobbs,et al. Oxazolidinones Mechanism of Action: Inhibition of the First Peptide Bond Formation* , 2001, The Journal of Biological Chemistry.
[58] A. Drlica-Wagner,et al. Enhancement of Fluoroquinolone Activity by C-8 Halogen and Methoxy Moieties: Action against a Gyrase Resistance Mutant of Mycobacterium smegmatis and a Gyrase-Topoisomerase IV Double Mutant of Staphylococcus aureus , 2001, Antimicrobial Agents and Chemotherapy.
[59] E. Rubinstein. History of Quinolones and Their Side Effects , 2001, Chemotherapy.
[60] T. Silhavy,et al. Genetic Basis for Activity Differences Between Vancomycin and Glycolipid Derivatives of Vancomycin , 2001, Science.
[61] Marilyn Roberts,et al. Tetracycline Antibiotics: Mode of Action, Applications, Molecular Biology, and Epidemiology of Bacterial Resistance , 2001, Microbiology and Molecular Biology Reviews.
[62] K. Severinov,et al. The β′ Subunit of Escherichia coli RNA Polymerase Is Not Required for Interaction with Initiating Nucleotide but Is Necessary for Interaction with Rifampicin* , 2001, The Journal of Biological Chemistry.
[63] Arkady Mustaev,et al. Structural Mechanism for Rifampicin Inhibition of Bacterial RNA Polymerase , 2001, Cell.
[64] T. Steitz,et al. The structural basis of ribosome activity in peptide bond synthesis. , 2000, Science.
[65] T. Nyström,et al. Protein oxidation in response to increased transcriptional or translational errors. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[66] Kenneth W. Bayles,et al. The Staphylococcus aureus lrgAB Operon Modulates Murein Hydrolase Activity and Penicillin Tolerance , 2000, Journal of bacteriology.
[67] J. Hoch,et al. Two-component and phosphorelay signal transduction. , 2000, Current opinion in microbiology.
[68] Roger A. Garrett,et al. The Ribosome, Structure, Function, Antibiotics, and Cellular Interactions , 2000 .
[69] F. Fang,et al. Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase. , 2000, Science.
[70] Myron F. Goodman,et al. The importance of repairing stalled replication forks , 2000, Nature.
[71] T. Pape,et al. Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome , 2000, Nature Structural Biology.
[72] D. Williams,et al. Binding of glycopeptide antibiotics to a model of a vancomycin-resistant bacterium. , 1999, Chemistry & biology.
[73] S. Normark,et al. Emergence of vancomycin tolerance in Streptococcus pneumoniae , 1999, Nature.
[74] Zhong Chen,et al. Vancomycin derivatives that inhibit peptidoglycan biosynthesis without binding D-Ala-D-Ala. , 1999, Science.
[75] A. Maxwell,et al. The DNA Gyrase-Quinolone Complex , 1998, The Journal of Biological Chemistry.
[76] J. Höltje,et al. Growth of the Stress-Bearing and Shape-Maintaining Murein Sacculus of Escherichia coli , 1998, Microbiology and Molecular Biology Reviews.
[77] K. Drlica,et al. DNA gyrase, topoisomerase IV, and the 4-quinolones , 1997, Microbiology and molecular biology reviews : MMBR.
[78] Anthony Maxwell,et al. Crystal structure of the breakage–reunion domain of DNA gyrase , 1997, Nature.
[79] J. Puglisi,et al. Structure of the A Site of Escherichia coli 16S Ribosomal RNA Complexed with an Aminoglycoside Antibiotic , 1996, Science.
[80] E. Brunskill,et al. Identification of LytSR-regulated genes from Staphylococcus aureus , 1996, Journal of bacteriology.
[81] R. Muñoz,et al. ParC subunit of DNA topoisomerase IV of Streptococcus pneumoniae is a primary target of fluoroquinolones and cooperates with DNA gyrase A subunit in forming resistance phenotype , 1996, Antimicrobial agents and chemotherapy.
[82] A. Maxwell,et al. DNA cleavage is not required for the binding of quinolone drugs to the DNA gyrase-DNA complex. , 1996, Biochemistry.
[83] M. Snyder,et al. DNA gyrase and topoisomerase IV on the bacterial chromosome: quinolone-induced DNA cleavage. , 1996, Journal of molecular biology.
[84] M. Ehrenberg,et al. Dissociation rate of cognate peptidyl-tRNA from the A-site of hyper-accurate and error-prone ribosomes. , 1994, European journal of biochemistry.
[85] W. M. Huang,et al. Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone‐resistant isolates , 1994, Molecular microbiology.
[86] J. Smith,et al. Function of the SOS Process in Repair of DNA Damage Induced by Modern 4‐Quinolones , 1993, The Journal of pharmacy and pharmacology.
[87] E. Bi,et al. Cell division inhibitors SulA and MinCD prevent formation of the FtsZ ring , 1993, Journal of bacteriology.
[88] S. Vincent,et al. Lytic effect of two fluoroquinolones, ofloxacin and pefloxacin, on Escherichia coli W7 and its consequences on peptidoglycan composition , 1991, Antimicrobial Agents and Chemotherapy.
[89] S. Nakamura,et al. Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli , 1990, Antimicrobial Agents and Chemotherapy.
[90] A. Tomasz,et al. Two bactericidal targets for penicillin in pneumococci: autolysis-dependent and autolysis-independent killing mechanisms , 1990, Antimicrobial Agents and Chemotherapy.
[91] J. Smith,et al. 4-quinolones and the SOS response. , 1989, Journal of medical microbiology.
[92] B. D. Davis. Mechanism of bactericidal action of aminoglycosides , 1987, Microbiological reviews.
[93] B. D. Davis,et al. Misread protein creates membrane channels: an essential step in the bactericidal action of aminoglycosides. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[94] H. Taber,et al. Streptomycin accumulation by Bacillus subtilis requires both a membrane potential and cytochrome aa3 , 1986, Antimicrobial Agents and Chemotherapy.
[95] W. Wehrli,et al. Rifampin: mechanisms of action and resistance. , 1983, Reviews of infectious diseases.
[96] P. Sensi. History of the development of rifampin. , 1983, Reviews of infectious diseases.
[97] L. Bryan,et al. Roles of ribosomal binding, membrane potential, and electron transport in bacterial uptake of streptomycin and gentamicin , 1983, Antimicrobial Agents and Chemotherapy.
[98] D. Otto,et al. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes , 1982, Antimicrobial Agents and Chemotherapy.
[99] R. Hancock. Aminoglycoside uptake and mode of action-with special reference to streptomycin and gentamicin. II. Effects of aminoglycosides on cells. , 1981, The Journal of antimicrobial chemotherapy.
[100] R. Hancock. Aminoglycoside uptake and mode of action--with special reference to streptomycin and gentamicin. I. Antagonists and mutants. , 1981, The Journal of antimicrobial chemotherapy.
[101] J. Strominger,et al. Penicillins and cephalosporins are active site-directed acylating agents: evidence in support of the substrate analogue hypothesis. , 1980, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[102] A. Tomasz,et al. Triggering of autolytic cell wall degradation in Escherichia coli by beta-lactam antibiotics , 1979, Antimicrobial Agents and Chemotherapy.
[103] J. Rahal,et al. Bactericidal and Bacteriostatic Action of Chloramphenicol Against Meningeal Pathogens , 1979, Antimicrobial Agents and Chemotherapy.
[104] M. Snyder,et al. DNA gyrase on the bacterial chromosome: DNA cleavage induced by oxolinic acid. , 1979, Journal of molecular biology.
[105] L. E. Bryan,et al. Mechanism of Aminoglycoside Antibiotic Resistance in Anaerobic Bacteria: Clostridium perfringens and Bacteroides fragilis , 1979, Antimicrobial Agents and Chemotherapy.
[106] C. Cech,et al. On the mechanism of rifampicin inhibition of RNA synthesis. , 1978, The Journal of biological chemistry.
[107] K. Drlica,et al. Superhelical Escherichia coli DNA: relaxation by coumermycin. , 1978, Journal of molecular biology.
[108] M. Gellert,et al. Nalidixic acid resistance: a second genetic character involved in DNA gyrase activity. , 1977, Proceedings of the National Academy of Sciences of the United States of America.
[109] N. Cozzarelli,et al. Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. , 1977, Proceedings of the National Academy of Sciences of the United States of America.
[110] M. Gellert,et al. DNA gyrase: an enzyme that introduces superhelical turns into DNA. , 1976, Proceedings of the National Academy of Sciences of the United States of America.
[111] B. Spratt. Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12. , 1975, Proceedings of the National Academy of Sciences of the United States of America.
[112] G. Hobby,et al. The action of rifampin alone and in combination with other antituberculous drugs. , 1970, The American review of respiratory disease.
[113] A. Tomasz,et al. Multiple Antibiotic Resistance in a Bacterium with Suppressed Autolytic System , 1970, Nature.
[114] B. Weisblum,et al. Antibiotic Inhibitors of the Bacterial Ribosome , 1968, Bacteriological reviews.
[115] K. Honikel,et al. The specific inhibition of the DNA-directed RNA synthesis by rifamycin. , 1967, Biochimica et biophysica acta.
[116] D J Tipper,et al. Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine. , 1965, Proceedings of the National Academy of Sciences of the United States of America.
[117] J. Davies,et al. Misreading of RNA codewords induced by aminoglycoside antibiotics. , 1965, Molecular pharmacology.
[118] E. M. Wise,et al. Penicillin: its basic site of action as an inhibitor of a peptide cross-linking reaction in cell wall mucopeptide synthesis. , 1965, Proceedings of the National Academy of Sciences of the United States of America.
[119] P. Isaacson,et al. STREPTOMYCIN ACTION AND ANAEROBIOSIS. , 1965, Journal of general microbiology.
[120] W. Goss,et al. Mechanism of Action of Nalidixic Acid on Escherichia coli II. Inhibition of Deoxyribonucleic Acid Synthesis , 1965, Journal of bacteriology.
[121] W. Goss,et al. MECHANISM OF ACTION OF NALIDIXIC ACID ON ESCHERICHIA COLI , 1964, Journal of bacteriology.
[122] R. Hancock. Uptake of 14C-streptomycin by some microorganisms and its relation to their streptomycin sensitivity. , 1962, Journal of general microbiology.
[123] B. D. Davis,et al. Synergism between Streptomycin and Penicillin: A Proposed Mechanism , 1962, Science.
[124] B. D. Davis,et al. Effect of Streptomycin on Escherichia Coli: Uptake of Streptomycin by Escherichia coli , 1960, Nature.
[125] B. D. Davis,et al. Effect of Streptomycin on Escherichia Coli: Damage by Streptomycin to the Cell Membrane of Escherichia coli , 1960, Nature.
[126] A. Fleming,et al. On the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzæ , 1929 .
[127] P. Vannuffel,et al. Mechanism of Action of Streptogramins and Macrolides , 2012, Drugs.
[128] B. Stockwell,et al. Multicomponent therapeutics for networked systems , 2005, Nature Reviews Drug Discovery.
[129] John W. Beaber,et al. SOS response promotes horizontal dissemination of antibiotic resistance genes , 2004, Nature.
[130] J. Imlay. How oxygen damages microbes: oxygen tolerance and obligate anaerobiosis. , 2002, Advances in microbial physiology.
[131] Robert E W Hancock,et al. Role of membranes in the activities of antimicrobial cationic peptides. , 2002, FEMS microbiology letters.
[132] W. Burman,et al. Comparative Pharmacokinetics and Pharmacodynamics of the Rifamycin Antibacterials , 2001, Clinical pharmacokinetics.
[133] E. Charpentier,et al. Signal transduction by a death signal peptide: uncovering the mechanism of bacterial killing by penicillin. , 2000, Molecular cell.
[134] H. Hiasa,et al. Mechanism of Quinolone Action A DRUG-INDUCED STRUCTURAL PERTURBATION OF THE DNA PRECEDES STRAND CLEAVAGE BY TOPOISOMERASE IV* , 1997 .
[135] S. Donadio,et al. Macrolides. , 1995, Biotechnology.
[136] C. Walsh,et al. Intracellular steps of bacterial cell wall peptidoglycan biosynthesis: enzymology, antibiotics, and antibiotic resistance. , 1992, Natural product reports.
[137] H. C. Neu. Quinolone antimicrobial agents. , 1992, Annual review of medicine.
[138] J. Smith,et al. Protein- and RNA-synthesis independent bactericidal activity of ciprofloxacin that involves the A subunit of DNA gyrase. , 1991, Journal of medical microbiology.
[139] R. Young,et al. RNA polymerase II. , 1991, Annual review of biochemistry.
[140] F. Goldstein,et al. Bacteriostatic and bactericidal activity of azithromycin against Haemophilus influenzae. , 1990, The Journal of antimicrobial chemotherapy.
[141] R. G. Eagon,et al. The effect of mafenide on dihydropteroate synthase. , 1990, The Journal of antimicrobial chemotherapy.
[142] Y. Kono. Oxygen Enhancement of bactericidal activity of rifamycin SV on Escherichia coli and aerobic oxidation of rifamycin SV to rifamycin S catalyzed by manganous ions: the role of superoxide. , 1982, Journal of biochemistry.
[143] A. Tomasz,et al. The mechanism of the irreversible antimicrobial effects of penicillins: how the beta-lactam antibiotics kill and lyse bacteria. , 1979, Annual review of microbiology.
[144] M. Scrutton. Divalent metal ion catalysis of the oxidation of rifamycin SV to refamycin S , 1977, FEBS letters.
[145] M. Chamberlin,et al. Preface/Front Matter , 1976 .
[146] G. Porven,et al. [RIFOMYCIN. (A NEW ANTIBIOTIC)]. , 1963, Archivos argentinos de tisiologia y neumonologia.
[147] B. D. Davis,et al. Damage by streptomycin to the cell membrane of Escherichia coli. , 1960, Nature.
[148] B. D. Davis,et al. Uptake of streptomycin by Escherichia coli. , 1960, Nature.
[149] P. Margalith,et al. Rifomycin, a new antibiotic; preliminary report. , 1959, Il Farmaco; edizione scientifica.
[150] E. Brunskill,et al. Identification and Molecular Characterization of a Putative Regulatory Locus That Affects Autolysis in Staphylococcus aureus , 2022 .