4-methylpyrazole protects against acetaminophen-induced acute kidney injury.
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H. Jaeschke | A. Ramachandran | B. Rumack | S. Curry | J. Akakpo | H. Orhan
[1] H. Jaeschke,et al. A mitochondrial journey through acetaminophen hepatotoxicity. , 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[2] A. Scalzo,et al. Use of fomepizole as an adjunct in the treatment of acetaminophen overdose: a case series , 2020 .
[3] H. Jaeschke,et al. The Effect of 4-Methylpyrazole on Oxidative Metabolism of Acetaminophen in Human Volunteers , 2019, Journal of Medical Toxicology.
[4] M. Czaja,et al. Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability , 2019, Hepatology communications.
[5] P. Murray,et al. Biomarker Predictors of Adverse Acute Kidney Injury Outcomes in Critically Ill Patients: The Dublin Acute Biomarker Group Evaluation Study , 2019, American Journal of Nephrology.
[6] M. Saleem,et al. A Rare Case of Acetaminophen Toxicity Leading to Severe Kidney Injury , 2019, Cureus.
[7] Aaron B. Skolnik,et al. The Relationship Between Circulating Acetaminophen-Protein Adduct Concentrations and Alanine Aminotransferase Activities in Patients With and Without Acetaminophen Overdose and Toxicity , 2019, Journal of Medical Toxicology.
[8] M. Manns,et al. Outcomes of renal dysfunction in patients with acute liver failure , 2019, United European gastroenterology journal.
[9] H. Jaeschke,et al. Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase. , 2019, Toxicological sciences : an official journal of the Society of Toxicology.
[10] H. Jaeschke,et al. Acetaminophen Hepatotoxicity , 2019, Seminars in Liver Disease.
[11] L. Jafri,et al. The utility of neutrophil gelatinase-associated Lipocalin (NGAL) as a marker of acute kidney injury (AKI) in critically ill patients , 2019, Biomarker Research.
[12] S. Curry,et al. Evaluation and treatment of acetaminophen toxicity. , 2019, Advances in pharmacology.
[13] J. Kellum,et al. Global epidemiology and outcomes of acute kidney injury , 2018, Nature Reviews Nephrology.
[14] B. Turna,et al. Inter-individual and inter-organ variability in the bioactivation of paracetamol by human liver and kidney tissues. , 2018, Environmental toxicology and pharmacology.
[15] H. Jaeschke,et al. 4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes , 2018, Human & experimental toxicology.
[16] Mitchell R. McGill,et al. Extrahepatic toxicity of acetaminophen: critical evaluation of the evidence and proposed mechanisms , 2017, Journal of clinical and translational research.
[17] M. Kutner,et al. Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update , 2016, Journal of clinical and translational hepatology.
[18] Mitchell R. McGill,et al. A direct comparison of methods used to measure oxidized glutathione in biological samples: 2-vinylpyridine and N-ethylmaleimide , 2015, Toxicology mechanisms and methods.
[19] J. Lai,et al. Kidney Failure and Liver Allocation: Current Practices and Potential Improvements. , 2015, Advances in chronic kidney disease.
[20] Thomas M. Leventhal,et al. What a Nephrologist Needs to Know About Acute Liver Failure. , 2015, Advances in chronic kidney disease.
[21] H. Jaeschke. Acetaminophen: Dose-Dependent Drug Hepatotoxicity and Acute Liver Failure in Patients , 2015, Digestive Diseases.
[22] William M. Lee,et al. Risk factors and outcomes of acute kidney injury in patients with acute liver failure. , 2015, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[23] Mitchell R. McGill,et al. Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase. , 2014, Toxicology and applied pharmacology.
[24] B. Bhushan,et al. Pro-regenerative signaling after acetaminophen-induced acute liver injury in mice identified using a novel incremental dose model. , 2014, The American journal of pathology.
[25] Mitchell R. McGill,et al. Mechanisms of acetaminophen-induced cell death in primary human hepatocytes. , 2014, Toxicology and applied pharmacology.
[26] P. Hayes,et al. Acute kidney injury in acute liver failure: a review , 2013, Expert review of gastroenterology & hepatology.
[27] J. Brouard,et al. Insuffisance rénale secondaire à une intoxication au paracétamol : à propos de 3 cas , 2013 .
[28] Mitchell R. McGill,et al. Metabolism and Disposition of Acetaminophen: Recent Advances in Relation to Hepatotoxicity and Diagnosis , 2013, Pharmaceutical Research.
[29] Hartmut Jaeschke,et al. Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity. , 2012, Toxicology and applied pharmacology.
[30] Michael J Hodgman,et al. A review of acetaminophen poisoning. , 2012, Critical care clinics.
[31] Hartmut Jaeschke,et al. The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation. , 2012, The Journal of clinical investigation.
[32] B. Hendry,et al. Acute kidney injury in patients admitted to a liver intensive therapy unit with paracetamol-induced hepatotoxicity. , 2011, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[33] Y. Masubuchi,et al. Sex difference in susceptibility to acetaminophen hepatotoxicity is reversed by buthionine sulfoximine. , 2011, Toxicology.
[34] K. Bek,et al. A case of acetaminophen (paracetamol) causing renal failure without liver damage in a child and review of literature , 2010, Renal failure.
[35] J. Brent. Fomepizole for ethylene glycol and methanol poisoning. , 2009, The New England journal of medicine.
[36] J. Neuberger,et al. Outcomes of liver transplantation for paracetamol (acetaminophen)‐induced hepatic failure , 2009, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[37] T. Rimmelé,et al. Insuffisance rénale aiguë lors d’intoxication à l’acétaminophène: à propos de trois cas , 2009 .
[38] P. Hayes,et al. The systemic inflammatory response syndrome is predictive of renal dysfunction in patients with non-paracetamol-induced acute liver failure , 2008, Gut.
[39] K. Heard,et al. Acetylcysteine for acetaminophen poisoning. , 2008, The New England journal of medicine.
[40] D. Waxman,et al. Determination of CYP2B6 component of 7-ethoxy-4-trifluoromethylcoumarin O-deethylation activity in human liver microsomes. , 2006, Methods in molecular biology.
[41] H. Jaeschke,et al. Peroxynitrite-Induced Mitochondrial and Endonuclease-Mediated Nuclear DNA Damage in Acetaminophen Hepatotoxicity , 2005, Journal of Pharmacology and Experimental Therapeutics.
[42] Steven D. Cohen,et al. Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity in CD-1 mice: I. Enhancement of acetaminophen nephrotoxicity by acetaminophen-cysteine. , 2005, Toxicology and applied pharmacology.
[43] Steven D. Cohen,et al. Standard of care may not protect against acetaminophen-induced nephrotoxicity. , 2004, Basic & clinical pharmacology & toxicology.
[44] D. Ng,et al. Hepatotoxicity and persistent renal insufficiency after repeated supratherapeutic paracetamol ingestion in a Chinese boy. , 2004, Hong Kong medical journal = Xianggang yi xue za zhi.
[45] J. Manautou,et al. Hepatobiliary excretion of acetaminophen glutathione conjugate and its derivatives in transport-deficient (TR-) hyperbilirubinemic rats. , 2003, Drug metabolism and disposition: the biological fate of chemicals.
[46] E. Hazai,et al. Reduction of toxic metabolite formation of acetaminophen. , 2002, Biochemical and biophysical research communications.
[47] M. Shannon,et al. Nephrotoxicity After Acute Severe Acetaminophen Poisoning in Adolescents , 2001, Journal of toxicology. Clinical toxicology.
[48] L. Lash,et al. Expression of glutathione-dependent enzymes and cytochrome P450s in freshly isolated and primary cultures of proximal tubular cells from human kidney. , 2000, The Journal of pharmacology and experimental therapeutics.
[49] D. Eaton,et al. Role of CYP1A2 in the hepatotoxicity of acetaminophen: investigations using Cyp1a2 null mice. , 1998, Toxicology and applied pharmacology.
[50] D. Waxman,et al. Determination of the CYP2B6 component of 7-ethoxy-4-trifluoromethylcoumarin O-deethylation activity in human liver microsomes. , 1998, Methods in molecular biology.
[51] B. Materson,et al. Acetaminophen‐Related Acute Renal Failure without Fulminant Liver Failure , 1997, Pharmacotherapy.
[52] P. Blakely,et al. Acute renal failure due to acetaminophen ingestion: a case report and review of the literature. , 1995, Journal of the American Society of Nephrology : JASN.
[53] Steven D. Cohen,et al. Immunohistochemical localization of acetaminophen in target tissues of the CD-1 mouse: correspondence of covalent binding with toxicity. , 1995, Fundamental and applied toxicology : official journal of the Society of Toxicology.
[54] Steven D. Cohen,et al. Gender-related differences in susceptibility to acetaminophen-induced protein arylation and nephrotoxicity in the CD-1 mouse. , 1995, Toxicology and applied pharmacology.
[55] Steven D. Cohen,et al. Acetaminophen nephrotoxicity in CD-1 mice. I. Evidence of a role for in situ activation in selective covalent binding and toxicity. , 1994, Toxicology and applied pharmacology.
[56] N. Ballatori,et al. Glutathione conjugation and conversion to mercapturic acids can occur as an intrahepatic process. , 1994, Journal of toxicology and environmental health.
[57] J. Buters,et al. A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man. Direct fluorescence monitoring of the deethylation of 7-ethoxy-4-trifluoromethylcoumarin. , 1993, Biochemical pharmacology.
[58] A. Jones,et al. Paracetamol poisoning and the kidney , 1993, Journal of clinical pharmacy and therapeutics.
[59] S. Emeighhart. Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse. , 1991 .
[60] S. D. Cohen,et al. Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse. , 1991, Toxicology and applied pharmacology.
[61] A. Davenport,et al. Paracetamol (acetaminophen) poisoning resulting in acute renal failure without hepatic coma. , 1988, Nephron.
[62] M. Aurell,et al. Acute renal failure after analgesic drugs including paracetamol (acetaminophen). , 1988, Nephron.
[63] Steven D. Cohen,et al. Extrahepatic Lesions Induced by Acetaminophen in the Mouse , 1987, Toxicologic pathology.
[64] W. Weber,et al. Biochemical characterization of genetically variant aromatic amine N-acetyltransferases in A/J and C57BL/6J mice. , 1982, The Journal of biological chemistry.
[65] D. Kerr,et al. Paracetamol-induced acute renal failure in the absence of fulminant liver damage. , 1982, British medical journal.
[66] W. H. Jeffery,et al. Acute renal failure after acetaminophen overdose: report of two cases. , 1981, American journal of hospital pharmacy.
[67] J. Kleinman,et al. Acute renal failure associated with acetaminophen ingestion: report of a case and review of the literature. , 1980, Clinical nephrology.
[68] J. Critchley,et al. Intravenous N-acetylcysteine: still the treatment of choice for paracetamol poisoning. , 1979, British medical journal.
[69] J. Critchley,et al. Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning. , 1979, British medical journal.