Tranexamic acid inhibits melanogenesis by activating the autophagy system in cultured melanoma cells.

[1]  N. Borgese,et al.  Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS , 2015, Cells.

[2]  S. Chang,et al.  Hesperidin, A Popular Antioxidant Inhibits Melanogenesis via Erk1/2 Mediated MITF Degradation , 2015, International journal of molecular sciences.

[3]  S. Chang,et al.  Tranexamic Acid Diminishes Laser-Induced Melanogenesis , 2015, Annals of dermatology.

[4]  Y. Li,et al.  MAPK/JNK signalling: a potential autophagy regulation pathway , 2015, Bioscience reports.

[5]  S. Mishra,et al.  Effect of low dose tranexamic acid on intra-operative blood loss in neurosurgical patients , 2015, Saudi journal of anaesthesia.

[6]  Ji-Hyun Shin,et al.  Autophagy mediates anti-melanogenic activity of 3'-ODI in B16F1 melanoma cells. , 2013, Biochemical and biophysical research communications.

[7]  A. Hachiya,et al.  Autophagy has a significant role in determining skin color by regulating melanosome degradation in keratinocytes. , 2013, The Journal of investigative dermatology.

[8]  M. Saleem,et al.  mTOR plays a critical role in p53-induced oxidative kidney cell injury in HIVAN. , 2013, American journal of physiology. Renal physiology.

[9]  A. Shahid,et al.  Tranexamic acid in decreasing blood loss during and after caesarean section. , 2013, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.

[10]  E. Hui,et al.  Tranexamic acid: an important adjuvant in the treatment of melasma , 2013, Journal of cosmetic dermatology.

[11]  S. Wesselborg,et al.  Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks , 2011, Molecular and Cellular Biology.

[12]  Li-chen Wu,et al.  Antimelanogenic effect of c-phycocyanin through modulation of tyrosinase expression by upregulation of ERK and downregulation of p38 MAPK signaling pathways , 2011, Journal of Biomedical Science.

[13]  A. Ganesan,et al.  The pleiotropic roles of autophagy regulators in melanogenesis , 2011, Pigment cell & melanoma research.

[14]  W. Fong,et al.  Involvement of p38 MAPK signaling pathway in the anti-melanogenic effect of San-bai-tang, a Chinese herbal formula, in B16 cells. , 2010, Journal of ethnopharmacology.

[15]  Qing Jun Wang,et al.  The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond. , 2010, Trends in cell biology.

[16]  D. Massi,et al.  Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions. , 2010, Human pathology.

[17]  Ji-Ho Park,et al.  Inhibitory effects of arbutin on melanin biosynthesis of α-melanocyte stimulating hormone-induced hyperpigmentation in cultured brownish guinea pig skin tissues , 2009, Archives of pharmacal research.

[18]  Y. Ohsumi,et al.  Dynamics and function of PtdIns(3)P in autophagy , 2008, Autophagy.

[19]  Graça Raposo,et al.  Melanosomes — dark organelles enlighten endosomal membrane transport , 2007, Nature Reviews Molecular Cell Biology.

[20]  Y. Tomita,et al.  Mechanism of the Inhibitory Effect of Tranexamic Acid on Melanogenesis in Cultured Human Melanocytes in the Presence of Keratinocyte-conditioned Medium , 2007 .

[21]  Ji-Ho Park,et al.  Inhibition of tyrosinase activity by N,N-unsubstituted selenourea derivatives. , 2005, Biological & pharmaceutical bulletin.

[22]  B. Gilchrest,et al.  Keratinocytes and fibroblasts in a human skin equivalent model enhance melanocyte survival and melanin synthesis after ultraviolet irradiation. , 1995, The Journal of investigative dermatology.

[23]  M. Jeong,et al.  Inhibitory effects of Asterina pectinifera extracts on melanin biosynthesis through tyrosinase activity. , 2013, International journal of molecular medicine.

[24]  N. Higashi.  Treatment of Melasma with Oral Tranexamic Acid , 1988 .