Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation
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J. Segreti | S. Baker | Robert G. Schmidt | H. McDonald | C. Faltynek | P. Kym | M. Kort | Jun Chen | S. Joshi | S. Didomenico | R. Perner | J. Mikusa | D. Gauvin | P. Han | Xufeng Zhang | W. Niforatos | B. Bianchi | C. Zhong | G. Simler | S. McGaraughty | K. Chu | R. Reilly
[1] A. Patapoutian,et al. TRPA1 Contributes to Cold Hypersensitivity , 2010, The Journal of Neuroscience.
[2] G. Bedoya,et al. A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome , 2010, Neuron.
[3] B. Lumb,et al. Transient receptor potential channel A1 and noxious cold responses in rat cutaneous nociceptors , 2010, Neuroscience.
[4] A. A. Romanovsky,et al. The Transient Receptor Potential Vanilloid-1 Channel in Thermoregulation: A Thermosensor It Is Not , 2009, Pharmacological Reviews.
[5] A. Pertovaara,et al. Attenuation of Mechanical Hypersensitivity by an Antagonist of the TRPA1 Ion Channel in Diabetic Animals , 2009, Anesthesiology.
[6] M. Decker,et al. Pharmacological modulation of movement-evoked pain in a rat model of osteoarthritis. , 2009, European journal of pharmacology.
[7] Fuminori Kawabata,et al. Intragastric Administration of TRPV1, TRPV3, TRPM8, and TRPA1 Agonists Modulates Autonomic Thermoregulation in Different Manners in Mice , 2009, Bioscience, biotechnology, and biochemistry.
[8] D. Corey,et al. TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons , 2009, The Journal of Neuroscience.
[9] D. Corey,et al. Burning Cold: Involvement of TRPA1 in Noxious Cold Sensation , 2009, The Journal of general physiology.
[10] P. Heppenstall,et al. TRPA1 and Cold Transduction: An Unresolved Issue? , 2009, The Journal of general physiology.
[11] R. Vennekens,et al. TRPA1 acts as a cold sensor in vitro and in vivo , 2009, Proceedings of the National Academy of Sciences.
[12] C. Stucky,et al. Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors , 2009, Molecular pain.
[13] Donghee Kim,et al. Pore dilation occurs in TRPA1 but not in TRPM8 channels , 2009, Molecular pain.
[14] P. Reeh. TRPA1-mediated nociception: Response to letter by Fischer et al , 2008, Neuroscience.
[15] C. Belmonte,et al. TRPA1 Channels Mediate Cold Temperature Sensing in Mammalian Vagal Sensory Neurons: Pharmacological and Genetic Evidence , 2008, The Journal of Neuroscience.
[16] P. Anand,et al. TRPA1 receptor localisation in the human peripheral nervous system and functional studies in cultured human and rat sensory neurons , 2008, Neuroscience Letters.
[17] M. Caterina. On the thermoregulatory perils of TRPV1 antagonism , 2008, PAIN.
[18] P. Hajduk,et al. Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels , 2008, The Journal of Neuroscience.
[19] S. Jordt,et al. TRPA1 is a major oxidant sensor in murine airway sensory neurons. , 2008, The Journal of clinical investigation.
[20] T. Neelands,et al. Transient receptor potential A1 mediates an osmotically activated ion channel , 2008, The European journal of neuroscience.
[21] D. Henze,et al. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity , 2008, Molecular pain.
[22] A. Basbaum,et al. 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1 , 2007, Proceedings of the National Academy of Sciences.
[23] Michael Zhao,et al. TRPA1 mediates formalin-induced pain , 2007, Proceedings of the National Academy of Sciences.
[24] M. E. Buck,et al. Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury. , 2007, Biochemical and biophysical research communications.
[25] A. A. Romanovsky,et al. Nonthermal Activation of Transient Receptor Potential Vanilloid-1 Channels in Abdominal Viscera Tonically Inhibits Autonomic Cold-Defense Effectors , 2007, The Journal of Neuroscience.
[26] Matthew S. Johnson,et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat , 2007, Proceedings of the National Academy of Sciences.
[27] J. Treanor,et al. The Vanilloid Receptor TRPV1 Is Tonically Activated In Vivo and Involved in Body Temperature Regulation , 2007, The Journal of Neuroscience.
[28] P. Heppenstall,et al. Direct activation of the ion channel TRPA1 by Ca2+ , 2007, Nature Neuroscience.
[29] Jing Xu,et al. Utility of Large-Scale Transiently Transfected Cells for Cell-Based High-Throughput Screens to Identify Transient Receptor Potential Channel A1 (TRPA1) Antagonists , 2007, Journal of biomolecular screening.
[30] A. Patapoutian,et al. A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition , 2007, Molecular pain.
[31] Yi Dai,et al. Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats , 2006, Experimental Neurology.
[32] Clifford J. Woolf,et al. TRPA1 Contributes to Cold, Mechanical, and Chemical Nociception but Is Not Essential for Hair-Cell Transduction , 2006, Neuron.
[33] David Julius,et al. TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents , 2006, Cell.
[34] Q. Shi,et al. Production of lipid peroxidation products in osteoarthritic tissues: new evidence linking 4-hydroxynonenal to cartilage degradation. , 2006, Arthritis and rheumatism.
[35] Yi Dai,et al. TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury. , 2005, The Journal of clinical investigation.
[36] A. Patapoutian,et al. Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin , 2004, Neuron.
[37] D. McKemy,et al. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1 , 2004, Nature.
[38] Peter McIntyre,et al. ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures , 2003, Cell.
[39] M. Harada,et al. [Pharmacological studies on Chinese cinnamon. I. Central effects of cinnamaldehyde]. , 1972, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.