Some neural and behavioral correlates of electrical self-stimulation of the limbic system.

Recent studies have demonstrated that behavior can be established and maintained in experimental animals using direct electrical stimulation of the brain as reinforcement (Delgado, Roberts, & Miller, 1954; Olds & Milner, 1954; Sidman, Brady, Boren, Conrad & Schulman, 1955). Following the original observations by Olds and Milner that localized brain stimulation could serve as a reward for lever pressing (Olds et al., 1954), several reports have described interaction effects involving electrical self-stimulation of selected brain areas and a wide variety of behavioral, physiological, and anatomical factors (Brady, 1957; Brady, 1956; Brady, 1958a; Brady, 1958b; Brady, Boren, Conrad & Sidman, 1957; Lilly, 1958; Miller, 1958; Olds, 1958a; Olds, 1955; Olds, 1956a; Olds, 1956b; Olds, 1958b; Olds, Killan & Bach-y-Rita, 1956). However, surprisingly little attention has been directed toward an analysis of the interrelationships between the physiological events associated with self-stimulation and the behavior of the self-stimulating animal. Toward this end the present study provides preliminary experimental observations correlating electroencephalographic and behavioral activity accompanying self-stimulation of several limbic system structures in monkeys.

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