Awareness of avian influenza (“bird flu”) among attendees of a primary healthcare clinic in Riyadh

To the Editor: I read with great interest the recently published article by Lafta and Kadhim1 in the Annals of Saudi Medicine and I appreciated the authors’ efforts and work. However, I would like to raise two points about viewing child obesity via a gender lens and interpreting the data of Table 2 in the manuscript. Both points are actually interrelated. The authors explained the sole significant association of BMI with >2 hours outdoor playing among boys aged 10-12 years by stating that “this may be due to the tribal custom that girls spend more time indoors”. I agree with the authors’ intention to discuss obesity and its risk factors from a gender perspective, especially in Arab countries. Even in nonArab cultures, Chen et al2 recommended the need for genderspecific approaches to prevent childhood obesity. However, the authors’ explanation was immaterial because they did not draw it from their data. The authors only found a significant association between longer outdoor exercise and BMI in the older cohort of the male sub-sample. Some studies in the Arab region proved that lack of exercise was associated significantly with obesity among children, whereas obesity in older adults is more prevalent among the least educated, nonsmokers, and those reporting a family history of obesity. For the authors to explain childhood obesity in a gender context, they have to prove that girls 10-12 years were more obese than boys, presumably because they spend fewer hours in outdoor playing than boys of the same age. On the contrary, the authors stated that “the difference [in obesity prevalence between boys and girls] was not statistically significant”. Moreover, the authors confused the reader in determining their reference category for the odds ratio (OR) of the risk factors in Table 2. They showed that the OR of first-born vs. lastborn child was 0.78, P=0.02, concluding in their result section that “first-born children [were] more frequently of normal weight than last-born children”. The same was mentioned for breast fed vs. bottle fed, as well as primary school vs. college educated parents, which implies that the second category, for the first three risk factors, was the reference category where OR=1. If the authors’ rule was applied for the remaining two variables in the table, outdoor playing and watching TV, then less than 2 hours of outdoor playing would be a protective factor for boys aged 10-12 years against overweight as OR was 0.47, P=0.004. Similarly, boys aged 7-9 years, who spend fewer hours watching TV, would be 2.98 times more likely to be overweight than others. Unfortunately, the reverse was stated in the results and such a discrepancy could be explained, in the best case scenario, by misplacing the categories in Table 2 for the last two variables. To conclude, the authors were imprecise and inaccurate in their interpretation and their gender approach as regards the last two variables in Table 2.

[1]  P. Palese,et al.  Making Better Influenza Virus Vaccines? , 2006, Emerging infectious diseases.

[2]  Adolfo García-Sastre,et al.  Antiviral Response in Pandemic Influenza Viruses , 2006, Emerging infectious diseases.

[3]  Y. Guan,et al.  H5N1 Outbreaks and Enzootic Influenza , 2006, Emerging infectious diseases.

[4]  E. D. Kilbourne Influenza Pandemics of the 20th Century , 2006, Emerging infectious diseases.

[5]  A. Monto,et al.  Vaccines and Antiviral Drugs in Pandemic Preparedness , 2006, Emerging infectious diseases.

[6]  P. Horby,et al.  Nonpharmaceutical Interventions for Pandemic Influenza, National and Community Measures , 2006, Emerging infectious diseases.

[7]  K. Subbarao,et al.  Vaccines for Pandemic Influenza , 2006, Emerging infectious diseases.

[8]  Anthony S. Fauci,et al.  Pandemic Influenza Threat and Preparedness , 2006, Emerging infectious diseases.

[9]  T. Lancet Crunch time for summit on avian and human influenza , 2005, The Lancet.

[10]  S. Bradley,et al.  General practitioners with a special interest in public health; at last a way to deliver public health in primary care , 2005, Journal of Epidemiology and Community Health.

[11]  P. Imperato The Growing Challenge of Avian Influenza , 2005, Journal of Community Health.

[12]  S. Thacker,et al.  The evidence base for public health informing policy at the Centers for Disease Control and Prevention. , 2005, American journal of preventive medicine.

[13]  R. Lafta,et al.  Childhood obesity in Iraq: prevalence and possible risk factors , 2005, Annals of Saudi medicine.

[14]  C. Yeh,et al.  Risk factors for childhood obesity in elementary school-age Taiwanese children. , 2005, Progress in cardiovascular nursing.

[15]  T. Jones,et al.  Insulin pump therapy in children and adolescents: improvements in key parameters of diabetes management including quality of life , 2005, Diabetic medicine : a journal of the British Diabetic Association.

[16]  E. Gracely,et al.  The Effects of Low-Carbohydrate versus Conventional Weight Loss Diets in Severely Obese Adults: One-Year Follow-up of a Randomized Trial , 2004, Annals of Internal Medicine.

[17]  C. Padovani,et al.  Diets rich in saturated and polyunsaturated fatty acids: metabolic shifting and cardiac health. , 2004, Nutrition.

[18]  A. Sibai,et al.  Prevalence and covariates of obesity in Lebanon: findings from the first epidemiological study. , 2003, Obesity research.

[19]  Y. Bo-Abbas,et al.  Ketogenic diet modifies the risk factors of heart disease in obese patients. , 2003, Nutrition.

[20]  D. Rader,et al.  A randomized trial of a low-carbohydrate diet for obesity. , 2003, The New England journal of medicine.

[21]  K. Sakhaee,et al.  Effect of low-carbohydrate high-protein diets on acid-base balance, stone-forming propensity, and calcium metabolism. , 2003, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[22]  K. Sakhaee,et al.  Effect of low-carbohydrate high-protein diets on acid-base balance, stone-forming propensity, and calcium metabolism , 2002 .

[23]  R. Eckel,et al.  Dietary Protein and Weight Reduction , 2001 .

[24]  James W. Anderson,et al.  Health Advantages and Disadvantages of Weight-Reducing Diets: A Computer Analysis and Critical Review , 2000, Journal of the American College of Nutrition.

[25]  P. Christie,et al.  Chinese avian influenza , 1998, BMJ.

[26]  T. Van Itallie,et al.  Composition of weight lost during short-term weight reduction. Metabolic responses of obese subjects to starvation and low-calorie ketogenic and nonketogenic diets. , 1976, The Journal of clinical investigation.

[27]  Y. Guan,et al.  H 5 N 1 Outbreaks and Enzootic Influenza-1 , 2007 .

[28]  Darrell M. Wilson,et al.  A two-center randomized controlled feasibility trial of insulin pump therapy in young children with diabetes. , 2005, Diabetes care.

[29]  Mph TM Pascal James Imperato MD Newer Challenges for Influenza Prevention. Lessons from 2004–2005 , 2005, Journal of Community Health.

[30]  E. D. Kilbourne Influenza Pandemics of the 20 th Century , 2005 .

[31]  G. Rassool Unprecedented spread of avian influenza requires broad collaboration. , 2004, Journal of advanced nursing.

[32]  Arshag D Mooradian,et al.  Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications. , 2002, Diabetes care.

[33]  R. Eckel,et al.  Dietary protein and weight reduction: a statement for healthcare professionals from the Nutrition Committee of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association. , 2001, Circulation.

[34]  From the Centers for Disease Control and Prevention. Update: isolation of avian influenza A(H5N1) viruses from humans--Hong Kong, 1997-1998. , 1998, JAMA.

[35]  Isolation of avian influenza A(H5N1) viruses from humans--Hong Kong, May-December 1997. , 1997, MMWR. Morbidity and mortality weekly report.