Automated image analysis of alpha-particle autoradiographs of human bone

Abstract Further techniques [4,5] for the analysis of CR-39 α-particle autoradiographs have been developed for application to α-autoradiography of autopsy bone at natural levels for exposure. The most significant new approach is the use of fully automated image analysis using a system developed in this laboratory. A 5 cm × 5 cm autoradiograph of tissue in which the activity is below 1 Bq kg −1 is scanned to both locate and measure the recorded α-particle tracks at a rate of 5 cm 2 /h. Improved methods of calibration have also been developed. The techniques are described and in order to illustrate their application, a bone sample contaminated with 239 Pu is analysed. Results from natural levels are the subject of a separate publication.