Fatores associados à maior mortalidade e tempo de internação prolongado em uma unidade de terapia intensiva de adultos

OBJETIVO: A unidade de terapia intensiva e sinonimo de gravidade e apresenta taxa de mortalidade entre 5,4% e 33%. Com o aperfeicoamento de novas tecnologias, o paciente pode ser mantido por longo periodo nessa unidade, ocasionando altos custos financeiros, morais e psicologicos para todos os envolvidos. O objetivo do presente estudo foi avaliar os fatores associados a maior mortalidade e tempo de internacao prolongado em uma unidade de terapia intensiva adulto. METODOS: Participaram deste estudo todos os pacientes admitidos consecutivamente na unidade de terapia intensiva de adultos, clinica/cirurgica do Hospital das Clinicas da Universidade Estadual de Campinas, no periodo de seis meses. Foram coletados dados como: sexo, idade, diagnostico, antecedentes pessoais, APACHE II, dias de ventilacao mecânica invasiva, reintubacao orotraqueal, traqueostomia, dias de internacao na unidade de terapia intensiva, alta ou obito na unidade de terapia intensiva. RESULTADOS: Foram incluidos no estudo 401 pacientes, sendo 59,6% homens e 40,4% mulheres, com idade media de 53,8±18,0 anos. A media de internacao na unidade de terapia intensiva foi de 8,2±10,8 dias, com taxa de mortalidade de 13,46%. Dados significativos para mortalidade e tempo de internacao prolongado em unidade de terapia intensiva (p 11, traqueostomia e reintubacao. CONCLUSAO: APACHE >11, traqueostomia e reintubacao estiveram associados, neste estudo, a maior taxa de mortalidade e tempo de permanencia prolongado em unidade de terapia intensiva.

[1]  J. Friedrich,et al.  Long-term outcomes and clinical predictors of hospital mortality in very long stay intensive care unit patients: a cohort study , 2006, Critical care.

[2]  C. Seymour,et al.  The outcome of extubation failure in a community hospital intensive care unit: a cohort study , 2004, Critical Care.

[3]  Shengwang Liu,et al.  RESEARCH Open Access , 1996 .

[4]  Salvador Benito,et al.  Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study. , 2002, JAMA.

[5]  P. Pronovost,et al.  Survival and functional outcome after prolonged intensive care unit stay. , 2000, Annals of surgery.

[6]  A. Erbay,et al.  Evaluation of risk factors for mortality in intensive care units: a prospective study from a referral hospital in Turkey. , 2005, American journal of infection control.

[7]  B. Guidet,et al.  Should elderly patients be admitted to the intensive care unit? , 2007, Intensive Care Medicine.

[8]  J. Norrie,et al.  Outcome of long-stay intensive care patients , 2001, Intensive Care Medicine.

[9]  W. Sibbald,et al.  Sex-and age-based differences in the delivery and outcomes of critical care , 2007, Canadian Medical Association Journal.

[10]  P. Hazard,et al.  A prospective, randomized, study comparing early percutaneous dilational tracheotomy to prolonged translaryngeal intubation (delayed tracheotomy) in critically ill medical patients* , 2004, Critical care medicine.

[11]  Sean Muldoon,et al.  Management of patients requiring prolonged mechanical ventilation: report of a NAMDRC consensus conference. , 2005, Chest.

[12]  W. Knaus,et al.  APACHE II: a severity of disease classification system. , 1985 .

[13]  M. Sánchez-Palacios,et al.  Características y pronóstico de los pacientes mayores con estancia muy prolongada en una Unidad de Cuidados Intensivos , 2008 .

[14]  M. Shabot,et al.  A 2-minute pre-extubation protocol for ventilated intensive care unit patients. , 2008, American journal of surgery.

[15]  J. Baudot,et al.  Morbidity, mortality, and quality-of-life outcomes of patients requiring ≥14 days of mechanical ventilation , 2003, Critical care medicine.

[16]  D. Pierson Tracheostomy and weaning. , 2005, Respiratory care.

[17]  J. Finn,et al.  Long-term survival from intensive care: a review , 2005, Intensive Care Medicine.

[18]  A. Kramer,et al.  Prolonged acute mechanical ventilation: implications for hospital benchmarking. , 2009, Chest.

[19]  J. Finn,et al.  Effect of length of stay in intensive care unit on hospital and long-term mortality of critically ill adult patients. , 2010, British journal of anaesthesia.

[20]  Yaseen Arabi,et al.  A prospective study of prolonged stay in the intensive care unit: predictors and impact on resource utilization. , 2002, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[21]  S Sauer,et al.  A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation. , 1997, Critical care medicine.

[22]  S. Caroleo,et al.  Weaning from mechanical ventilation: an open issue. , 2007, Minerva anestesiologica.

[23]  Stanley Lemeshow,et al.  Early indicators of prolonged intensive care unit stay: Impact of illness severity, physician staffing, and pre–intensive care unit length of stay , 2003, Critical care medicine.

[24]  M. Ferrer Non-invasive ventilation in the weaning process. , 2008, Minerva anestesiologica.

[25]  J. Takala,et al.  Resource use in the ICU: short‐ vs. long‐term patients * , 2003, Acta anaesthesiologica Scandinavica.

[26]  E. L’her,et al.  Impact of a nurses' protocol-directed weaning procedure on outcomes in patients undergoing mechanical ventilation for longer than 48 hours: a prospective cohort study with a matched historical control group , 2005, Critical care.

[27]  J. Kortbeek,et al.  Long-term mortality outcome associated with prolonged admission to the ICU. , 2006, Chest.

[28]  Ameen Abu-Hanna,et al.  Factors that predict outcome of intensive care treatment in very elderly patients: a review , 2005, Critical care.

[29]  Augusto Manoel de Carvalho Farias,et al.  Desmame e interrupção da ventilação mecânica , 2007 .