Localized Hyperthermia with Electromagnetic Arrays and the Leaky-Wave Troughguide Applicator

Noninvasive microwave hyperthermia is an attractive cancer treatment modality. Understanding the advantages and limitations of focusing are vital for the practical implementations of electromagnetic heating of deep tumors. These, as well as the important issues of tissue coupling and proper choices of polarization and frequency are herein examined. An optimal theoretical source distribution and an applicator design that approximates this distribution are discussed.

[1]  A. W. Guy,et al.  Analyses of Electromagnetic Fields Induced in Biological Tissues by Thermographic Studies on Equivalent Phantom Models , 1971 .

[2]  A. Guy,et al.  Nonionizing electromagnetic wave effects in biological materials and systems , 1972 .

[3]  J. Overgaard,et al.  Investigations on the possibility of a thermic tumour therapy. I. Short-wave treatment of a transplanted isologous mouse mammary carcinoma. , 1972, European journal of cancer.

[4]  G. Hahn,et al.  Tumor cure and cell survival after localized radiofrequency heating. , 1977, Cancer research.

[5]  P. P. Lele,et al.  Induction of deep, local hyperthermia by ultrasound and electromagnetic fields , 1980, Radiation and environmental biophysics.

[6]  K. Foster,et al.  RF-field interactions with biological systems: Electrical properties and biophysical mechanisms , 1980, Proceedings of the IEEE.

[7]  K. Foster,et al.  Dielectric properties of tumor and normal tissues at radio through microwave frequencies. , 1981, The Journal of microwave power.

[8]  Samaras Gm,et al.  Microwave hyperthermia for cancer therapy. , 1981 .

[9]  C. Durney,et al.  Hyperthermia production for cancer therapy: a review of fundamentals and methods. , 1981, The Journal of microwave power.

[10]  G. Hahn Hyperthermia for the Engineer: A Short Biological Primer , 1984, IEEE Transactions on Biomedical Engineering.

[11]  Robert J. Dickinson,et al.  An Ultrasound System for Local Hyperthermia Using Scanned Focused Transducers , 1984, IEEE Transactions on Biomedical Engineering.