A RANDOMIZED STUDY TO COMPARE THE EFFECT OF 0.5% HYPERBARIC BUPIVACAINE AND 1% 2-CHLOROPROCAINE IN SPINAL ANAESTHESIA IN ELECTIVE SHORT SURGICAL PROCEDURES

Background: The aim of this comparative study is to compare the effect of 0.5% hyperbaric bupivacaine and 1% 2-chloroprocaine in spinal anaesthesia. Materials and method : This study was conducted over a period of 18 months in which 12 months for study and 6 months for statistical analysis. The study population has been calculated by using G-power software with 80% of the power and 5% of the significance level. A total of 60 patients were taken as sample size for the study. Group A: Patients were given intrathecal 4ml of preservative free 1% 2-chloroprocaine (1ml = 10mg) and Group B: Patients were given intrathecal 1.5ml of 0.5% hyperbaric bupivacaine (1ml = 5mg). Results : The mean Onset of sensory block (min), Onset of motor block (min), Duration of motor blockade (min), Total time taken for two segment sensory regression (min), Total duration of sensory blockade (min)/ Duration of Analgesia and Time to ambulation (min) was significantly more among Group B compared to Group A. Conclusion : Chloroprocaine has the shortest time to complete recovery of sensory and motor block otherwise it was comparable

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