Diabetic retinopathy management guidelines

Diabetic retinopathy (DR) is an important cause of avoidable blindness worldwide. Seventy percent of diabetes occur in low and lower-middle income countries. Clinical practice guidelines for the management of DR have been implemented throughout the world, but mainly in developed nations. However, there is considerable variation between existing guidelines in the recommended frequency of referral, methods for examination and personnel involved in screening and review. This review compares the differences between current available guidelines in the context of the current medical evidence and also addresses the implications for management of DR in countries with limited resources.

[1]  S. Fine,et al.  Symposium on the treatment of diabetic retinopathy , 1969 .

[2]  S. Riaskoff Photocoagulation treatment of proliferative diabetic retinopathy. , 1981, Bulletin de la Societe belge d'ophtalmologie.

[3]  D L DeMets,et al.  The Wisconsin epidemiologic study of diabetic retinopathy. III. Prevalence and risk of diabetic retinopathy when age at diagnosis is 30 or more years. , 1984, Archives of ophthalmology.

[4]  D. DeMets,et al.  The Wisconsin epidemiologic study of diabetic retinopathy. II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years. , 1984, Archives of ophthalmology.

[5]  D. DeMets,et al.  Retinopathy in Young-onset Diabetic Patients , 1985, Diabetes Care.

[6]  R. Klein,et al.  Diabetic retinopathy as detected using ophthalmoscopy, a nonmydriatic camera and a standard fundus camera. , 1985, Ophthalmology.

[7]  Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1. Early Treatment Diabetic Retinopathy Study research group. , 1985, Archives of ophthalmology.

[8]  The management of diabetic eye disease. , 1985, Canadian family physician Medecin de famille canadien.

[9]  S. Nussey,et al.  Assessment of non-mydriatic fundus photography in detection of diabetic retinopathy. , 1986, British medical journal.

[10]  D L DeMets,et al.  The Wisconsin Epidemiologic Study of Diabetic Retinopathy. VI. Retinal photocoagulation. , 1987, Ophthalmology.

[11]  C. Jackson,et al.  Screening for diabetic retinopathy--comparison of a nurse and a doctor with retinal photography. , 1987, Diabetes research.

[12]  R. Kleinstein,et al.  Detection of diabetic retinopathy by optometrists. , 1987, Journal of the American Optometric Association.

[13]  F L Ferris,et al.  Photocoagulation for diabetic macular edema. , 1987, Archives of ophthalmology.

[14]  R. Klein,et al.  The Wisconsin epidemiological study of diabetic retinopathy: a review. , 1989, Diabetes/metabolism reviews.

[15]  D L DeMets,et al.  The Wisconsin Epidemiologic Study of Diabetic Retinopathy. IX. Four-year incidence and progression of diabetic retinopathy when age at diagnosis is less than 30 years. , 1989, Archives of ophthalmology.

[16]  R. T. Lienert Frcs,et al.  Inter-observer comparisons of ophthalmoscopic assessment of diabetic retinopathy. , 1989 .

[17]  D L DeMets,et al.  The Wisconsin Epidemiologic Study of Diabetic Retinopathy. X. Four-year incidence and progression of diabetic retinopathy when age at diagnosis is 30 years or more. , 1989, Archives of ophthalmology.

[18]  B. Klein,et al.  Effect of Pregnancy on Progression of Diabetic Retinopathy , 1990, Diabetes Care.

[19]  R. Klein,et al.  Is Menarche Associated With Diabetic Retinopathy? , 1990, Diabetes Care.

[20]  D M Steinwachs,et al.  Detecting and treating retinopathy in patients with type I diabetes mellitus. A health policy model. , 1990, Ophthalmology.

[21]  Early vitrectomy for severe vitreous hemorrhage in diabetic retinopathy. Four-year results of a randomized trial: Diabetic Retinopathy Vitrectomy Study Report 5. , 1990, Archives of ophthalmology.

[22]  M. Field,et al.  Clinical practice guidelines : directions for a new program , 1990 .

[23]  D. Spiegelhalter,et al.  Screening for Treatable Diabetic Retinopathy: a Comparison of Different Methods , 1991, Diabetic medicine : a journal of the British Diabetic Association.

[24]  Jonathan C. Javitt,et al.  Detecting and Treating Retinopathy in Patients with Tyke I Diabetes Mellitus: Savings Associated with Improved Implementation of Current Guidelines , 1991 .

[25]  Early Treatment Diabetic Retinopathy Study design and baseline patient characteristics. ETDRS report number 7. , 1991, Ophthalmology.

[26]  J. Khoury,et al.  Progression of diabetic retinopathy in pregnancy: association with hypertension in pregnancy. , 1992, American journal of obstetrics and gynecology.

[27]  Barbara E K Klein,et al.  Epidemiology of Proliferative Diabetic Retinopathy , 1992, Diabetes Care.

[28]  D. Singer,et al.  Screening for Diabetic Retinopathy , 1993, Diabetes Care.

[29]  J. A. Watters,et al.  Screening for Diabetic Retinopathy: The wide-angle retinal camera , 1993, Diabetes Care.

[30]  R. Klein,et al.  The association of microalbuminuria with diabetic retinopathy. The Wisconsin Epidemiologic Study of Diabetic Retinopathy. , 1993, Ophthalmology.

[31]  R. Klein,et al.  Is gross proteinuria a risk factor for the incidence of proliferative diabetic retinopathy? , 1993, Ophthalmology.

[32]  S. Harding,et al.  Sensitivity and specificity of photography and direct ophthalmoscopy in screening for sight threatening eye disease: the Liverpool diabetic eye study , 1995, BMJ.

[33]  E. Chew,et al.  Metabolic Control and Progression of Retinopathy: The Diabetes in Early Pregnancy Study , 1995, Diabetes Care.

[34]  M. van der Merwe,et al.  Screening for diabetic retinopathy in South Africa with 60° retinal colour photography , 1996 .

[35]  F. Ferris Early photocoagulation in patients with either type I or type II diabetes. , 1997, Transactions of the American Ophthalmological Society.

[36]  Screening for diabetic retinopathy in South Africa with 60 degrees retinal colour photography. , 1996, Journal of internal medicine.

[37]  Philip D. Harvey,et al.  Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38 , 1998, BMJ.

[38]  L. Holmes,et al.  The Diabetes in Early Pregnancy Study: beta-hydroxybutyrate levels in type 1 diabetic pregnancy compared with normal pregnancy. NICHD-Diabetes in Early Pregnancy Study Group (DIEP). National Institute of Child Health and Development. , 1998, Diabetes care.

[39]  R. Holman,et al.  Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group. , 1998 .

[40]  Catherine A. McCarty,et al.  Screening for diabetic retinopathy using a non-mydriatic retinal camera in rural Victoria. , 1998, Australian and New Zealand journal of ophthalmology.

[41]  N. Chaturvedi,et al.  The implementation of prompted retinal screening for diabetic eye disease by accredited optometrists in an inner‐city district of North London: a quality of care study , 1998, Diabetic medicine : a journal of the British Diabetic Association.

[42]  Stephen J. Aldington,et al.  United Kingdom Prospective Diabetes Study, 30: diabetic retinopathy at diagnosis of non-insulin-dependent diabetes mellitus and associated risk factors. , 1998, Archives of ophthalmology.

[43]  R. Holman,et al.  Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. , 1998 .

[44]  F. Ferris,et al.  Risk factors for high-risk proliferative diabetic retinopathy and severe visual loss: Early Treatment Diabetic Retinopathy Study Report #18. , 1998, Investigative ophthalmology & visual science.

[45]  A. Sjølie,et al.  Effect of lisinopril on progression of retinopathy in normotensive people with type 1 diabetes , 1998, The Lancet.

[46]  I J Constable,et al.  Non-mydriatic fundus photography: a viable alternative to fundoscopy for identification of diabetic retinopathy in an Aboriginal population in rural Western Australia? , 1998, Australian and New Zealand journal of ophthalmology.

[47]  H. Flynn,et al.  Vitrectomy in the management of diabetic retinopathy. , 1999, Survey of ophthalmology.

[48]  L. Dandona,et al.  Population based assessment of diabetic retinopathy in an urban population in southern India , 1999, The British journal of ophthalmology.

[49]  M. Obermaier,et al.  A telemedical approach to the screening of diabetic retinopathy: digital fundus photography. , 2000, Diabetes care.

[50]  K. Khunti,et al.  Effectiveness of screening and monitoring tests for diabetic retinopathy – a systematic review , 2000, Diabetic medicine : a journal of the British Diabetic Association.

[51]  Diabetes Control Effect of pregnancy on microvascular complications in the diabetes control and complications trial. The Diabetes Control and Complications Trial Research Group. , 2000, Diabetes care.

[52]  R. Klein,et al.  Understanding the value of diabetic retinopathy screening. , 2001, Archives of ophthalmology.

[53]  Stephen J. Aldington,et al.  UKPDS 50: Risk factors for incidence and progression of retinopathy in Type II diabetes over 6 years from diagnosis , 2001, Diabetologia.

[54]  A. Albert,et al.  Risk of developing retinopathy in Diabetes Control and Complications Trial type 1 diabetic patients with good or poor metabolic control. , 2001, Diabetes care.

[55]  L. Aiello,et al.  Stereo nonmydriatic digital-video color retinal imaging compared with Early Treatment Diabetic Retinopathy Study seven standard field 35-mm stereo color photos for determining level of diabetic retinopathy. , 2001, Ophthalmology.

[56]  T. Hisatomi,et al.  Triamcinolone-assisted pars plana vitrectomy improves the surgical procedures and decreases the postoperative blood–ocular barrier breakdown , 2002, Graefe's Archive for Clinical and Experimental Ophthalmology.

[57]  Retinopathy Screening in Children and Adolescents with Diabetes , 2002, Annals of the New York Academy of Sciences.

[58]  Catherine Kim,et al.  Gestational diabetes and the incidence of type 2 diabetes: a systematic review. , 2002, Diabetes care.

[59]  David Maberley,et al.  Digital photographic screening for diabetic retinopathy in the James Bay Cree , 2002, Ophthalmic epidemiology.

[60]  Francisco Gómez-Ulla,et al.  Digital retinal images and teleophthalmology for detecting and grading diabetic retinopathy. , 2002, Diabetes care.

[61]  H. King,et al.  Impact of poverty on the prevalence of diabetes and its complications in urban southern India , 2002, Diabetic medicine : a journal of the British Diabetic Association.

[62]  L. Bouter,et al.  Blood pressure, lipids, and obesity are associated with retinopathy: the hoorn study. , 2002, Diabetes care.

[63]  Matthew D. Davis,et al.  Effect of intensive therapy on the microvascular complications of type 1 diabetes mellitus. , 2002, JAMA.

[64]  A. Mainous,et al.  C-reactive protein, diabetes, and attendance at religious services. , 2002, Diabetes care.

[65]  C. Jackson,et al.  Can Australian general practitioners effectively screen for diabetic retinopathy? A pilot study , 2002, BMC family practice.

[66]  [Screening for diabetic retinopathy in the Czech Republic--guideline]. , 2002, Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti.

[67]  K. Schmid,et al.  The detection of diabetic retinopathy by Australian optometrists , 2002, Clinical & experimental optometry.

[68]  P. Mehler,et al.  Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes. , 2002, Kidney international.

[69]  P. L. Hildebrand,et al.  Clinical evaluation of patients with diabetic retinopathy: accuracy of the Inoveon diabetic retinopathy-3DT system. , 2002, Ophthalmology.

[70]  S. Hori Guidelines for the Management of Diabetic Retinopathy for the Internist , 2002 .

[71]  Aniruddha M. Deshpande,et al.  Standardized Reporting of Clinical Practice Guidelines: A Proposal from the Conference on Guideline Standardization , 2003, Annals of Internal Medicine.

[72]  Screening for diabetic retinopathy: a cause for concern in people who drive , 2003, Diabetic medicine : a journal of the British Diabetic Association.

[73]  F. Cluzeau,et al.  Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project , 2003 .

[74]  R. Klein Screening interval for retinopathy in type 2 diabetes , 2003, The Lancet.

[75]  A. Basu,et al.  Is digital image compression acceptable within diabetic retinopathy screening? , 2003, Diabetic medicine : a journal of the British Diabetic Association.

[76]  H. Taylor,et al.  Five‐year incidence of diabetic retinopathy in the Melbourne Visual Impairment Project , 2003, Clinical & experimental ophthalmology.

[77]  P. Scanlon,et al.  Comparison of two reference standards in validating two field mydriatic digital photography as a method of screening for diabetic retinopathy , 2003, The British journal of ophthalmology.

[78]  Beverley Balkau,et al.  The prevalence of and factors associated with diabetic retinopathy in the Australian population. , 2003, Diabetes care.

[79]  Matthew D. Davis,et al.  Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. , 2003, Ophthalmology.

[80]  Stanley Mirsky,et al.  Screening for diabetic retinopathy , 2003, The Lancet.

[81]  Graham P. Leese,et al.  A national retinal screening programme for diabetes in Scotland , 2003, Diabetic medicine : a journal of the British Diabetic Association.

[82]  R Greenwood,et al.  Grading and disease management in national screening for diabetic retinopathy in England and Wales , 2003, Diabetic medicine : a journal of the British Diabetic Association.

[83]  Simon P Harding,et al.  Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool Diabetic Eye Study: a cohort study , 2003, The Lancet.

[84]  Training GPs to screen for diabetic retinopathy. The impact of short term intensive education. , 2003, Australian family physician.

[85]  H. Dua,et al.  Royal College of Ophthalmologists , 2019, The Grants Register 2020.

[86]  J. Diamond,et al.  Accuracy of Screening for Diabetic Retinopathy by Family Physicians , 2004, The Annals of Family Medicine.

[87]  Ingrid U Scott,et al.  Single-field fundus photography for diabetic retinopathy screening: a report by the American Academy of Ophthalmology. , 2004, Ophthalmology.

[88]  P Gain,et al.  Screening for diabetic retinopathy in France. , 2004, Diabetes & metabolism.

[89]  J. Ellis,et al.  Effect of mydriasis and different field strategies on digital image screening of diabetic eye disease , 2004, British Journal of Ophthalmology.

[90]  C. Lawton Highlights of the 2003 Clinical Practice Guidelines for the prevention and management of diabetes in Canada. , 2004, CANNT journal = Journal ACITN.

[91]  S. Wild,et al.  Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. , 2004, Diabetes care.

[92]  Montip Tiensuwan,et al.  Screening for diabetic retinopathy in rural area using single-field, digital fundus images. , 2005, Journal of the Medical Association of Thailand = Chotmaihet thangphaet.

[93]  V. Mohan,et al.  Prevalence of diabetic retinopathy in urban India: the Chennai Urban Rural Epidemiology Study (CURES) eye study, I. , 2005, Investigative ophthalmology & visual science.

[94]  G. Roglić,et al.  Diabetes and associated disorders in Cambodia: two epidemiological surveys , 2005, The Lancet.

[95]  S. Binder,et al.  Vitrectomy for persistent diffuse diabetic macular edema. , 2005, American journal of ophthalmology.

[96]  P. Ryan,et al.  Incidence and progression of diabetic retinopathy in an Aboriginal Australian population: results from the Katherine Region Diabetic Retinopathy Study (KRDRS). Report no. 2 , 2005, Clinical and Experimental Ophthalmology.

[97]  Michael M. Engelgau,et al.  Prevalence of Diabetes and Impaired Fasting Glucose in Adults in the U.S. Population , 2006, Diabetes Care.

[98]  H. Limburg,et al.  Rapid assessment of avoidable blindness. , 2006, Community eye health.

[99]  J. Simpson,et al.  Intravitreal triamcinolone for refractory diabetic macular edema: two-year results of a double-masked, placebo-controlled, randomized clinical trial. , 2006, Ophthalmology.

[100]  A. Basu Digital image compression should be limited in diabetic retinopathy screening , 2006, Journal of telemedicine and telecare.

[101]  P. Mitchell,et al.  Temporal trends in the age-specific prevalence of diabetes and diabetic retinopathy in older persons: Population-based survey findings. , 2006, Diabetes research and clinical practice.

[102]  J. J. Wang,et al.  Five-year incidence and progression of diabetic retinopathy in a defined older population: the Blue Mountains Eye Study , 2007, Eye.

[103]  N. Levitt,et al.  Screening for diabetic retinopathy in primary care with a mobile fundal camera--evaluation of a South African pilot project. , 2007, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

[104]  M. Reed,et al.  Scottish Intercollegiate Guidelines Network (SIGN) 84 -- National Clinical Guideline for the Management of Breast Cancer in Women. , 2007, Clinical oncology (Royal College of Radiologists (Great Britain)).

[105]  I. Immonen,et al.  Glycodelin: a novel serum anti-inflammatory marker in type 1 diabetic retinopathy during pregnancy. , 2006, Acta ophthalmologica Scandinavica.

[106]  T. Wong,et al.  Management of diabetic retinopathy: a systematic review. , 2007, JAMA.

[107]  J. López‐Bastida,et al.  Sensitivity and specificity of digital retinal imaging for screening diabetic retinopathy , 2007, Diabetic medicine : a journal of the British Diabetic Association.

[108]  Linda Drake Prevention of Blindness from Diabetes Mellitus - Report of a WHO ConsultationPrevention of Blindness from Diabetes Mellitus - Report of a WHO Consultation , 2007 .

[109]  T. Das,et al.  Risk factors for diabetic retinopathy: Findings from The Andhra Pradesh Eye Disease Study , 2007, Clinical ophthalmology.

[110]  E. Wiltshire,et al.  Identifying children at particular risk of long‐term diabetes complications , 2007, Pediatric diabetes.

[111]  S. Fowler,et al.  The prevalence of retinopathy in impaired glucose tolerance and recent‐onset diabetes in the Diabetes Prevention Program , 2007, Diabetic medicine : a journal of the British Diabetic Association.

[112]  M. Rashidi,et al.  Four Years Incidence of Diabetic Retinopathy and Effective Factors on its Progression in Type II Diabetes , 2008, European journal of ophthalmology.

[113]  C. Thivolet,et al.  Screening of diabetic retinopathy: effect of field number and mydriasis on sensitivity and specificity of digital fundus photography. , 2008, Diabetes & metabolism.

[114]  Reply to ‘Evaluation of the effect of JPEG and JPEG2000 image compression on the detection of diabetic retinopathy’ , 2008, Eye.

[115]  Une rétinopathie diabétique proliférante inaugurant un diabète gestationnel , 2008 .

[116]  Concordancia en el estudio de retinografías en diabéticos: oftalmólogos vs médicos de familia , 2008 .

[117]  [Revised guideline 'Diabetic retinopathy: screening, diagnosis and treatment']. , 2008, Nederlands tijdschrift voor geneeskunde.

[118]  [Agreement among ophthalmologists and primary care physicians in the evaluation of retinographies of diabetic patients]. , 2008, Archivos de la Sociedad Espanola de Oftalmologia.

[119]  Naresh Mandava,et al.  Accuracy of Primary Care Clinicians in Screening for Diabetic Retinopathy Using Single-Image Retinal Photography , 2008, The Annals of Family Medicine.

[120]  R. Beck To mask or not to mask. , 2009, Archives of ophthalmology.

[121]  A. Avogaro,et al.  Screening for diabetic retinopathy: 1 and 3 nonmydriatic 45-degree digital fundus photographs vs 7 standard early treatment diabetic retinopathy study fields. , 2009, American journal of ophthalmology.

[122]  H. Al‐Mezaine,et al.  Pathophysiology and management of diabetic retinopathy , 2009 .

[123]  Farid Zayeri,et al.  Prevalence of diabetic retinopathy in Tehran province: a population-based study , 2009, BMC ophthalmology.

[124]  Guías de práctica clínica de la SERV: Manejo de las complicaciones oculares de la diabetes. Retinopatía diabética y edema macular , 2009 .

[125]  T. Danne,et al.  Foreword: DAWN Youth – time to make a real difference , 2009, Pediatric diabetes.

[126]  R. Klein,et al.  Rates of Progression in Diabetic Retinopathy During Different Time Periods , 2009, Diabetes Care.

[127]  D. Maahs,et al.  ISPAD Clinical Practice Consensus Guidelines 2014 Compendium , 2014 .

[128]  P. Heywood,et al.  Human Resources for Health Human Resources for Health at the District Level in Indonesia: the Smoke and Mirrors of Decentralization , 2022 .

[129]  Judy E. Kim,et al.  Three-year follow-up of a randomized trial comparing focal/grid photocoagulation and intravitreal triamcinolone for diabetic macular edema. , 2009, Archives of ophthalmology.

[130]  J. P. O’Hare,et al.  Higher Prevalence of Retinopathy in Diabetic Patients of South Asian Ethnicity Compared With White Europeans in the Community , 2009, Diabetes Care.

[131]  K. Ahmed Incidence of diabetic retinopathy : a 15 year follow up in a hospital population (Bangladesh) , 2009 .

[132]  G. Klingensmith,et al.  ISPAD clinical practice consensus guidelines 2009 compendium. Introduction. , 2009, Pediatric diabetes.

[133]  V. Gil-Guillén,et al.  Screening for sight threatening diabetic retinopathy using non‐mydriatic retinal camera in a primary care setting: to dilate or not to dilate? , 2009, International journal of clinical practice.

[134]  Rajiv Raman,et al.  Prevalence of diabetic retinopathy in India: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study report 2. , 2009, Ophthalmology.

[135]  [Guidelines of clinical practice of the SERV (Spanish Retina and Vitreous Society): management of ocular complications of diabetes. Diabetic retinopathy and macular oedema]. , 2009, Archivos de la Sociedad Espanola de Oftalmologia.

[136]  Ronald Klein,et al.  The Wisconsin Epidemiologic Study of Diabetic Retinopathy XXIII: the twenty-five-year incidence of macular edema in persons with type 1 diabetes. , 2009, Ophthalmology.

[137]  T. Vignesh,et al.  Prevalence and risk factors for diabetic retinopathy: a population-based assessment from Theni District, south India , 2009, Postgraduate Medical Journal.

[138]  D. Friedman,et al.  Prevalence of diabetic retinopathy in rural China: the Handan Eye Study. , 2009, Ophthalmology.

[139]  P. Damm,et al.  Progression of diabetic retinopathy during pregnancy in women with type 2 diabetes , 2010, Diabetologia.

[140]  Diagnosis and Treatment of Diabetic Retinopathy , 2010 .

[141]  B. Guerci,et al.  Progression de la rétinopathie diabétique chez les femmes enceintes : étude rétrospective monocentrique d’une série de 77 patientes consécutives , 2010 .

[142]  E. Mathiesen,et al.  Pregnancy‐induced sight‐threatening diabetic retinopathy in women with Type 1 diabetes , 2009, Diabetic medicine : a journal of the British Diabetic Association.

[143]  Lloyd Paul Aiello,et al.  Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema , 2010, Ophthalmology.

[144]  Walter T Ambrosius,et al.  Effects of medical therapies on retinopathy progression in type 2 diabetes. , 2010, The New England journal of medicine.

[145]  Guidelines for screening and treatment for diabetic retinopathy. , 2010 .

[146]  J. Ellis,et al.  Screening for Diabetic Retinopathy: A Comparative Trial of Photography and Scanning Laser Ophthalmoscopy , 2010, Ophthalmologica.

[147]  Elham Hatef,et al.  Two-year outcomes of the ranibizumab for edema of the mAcula in diabetes (READ-2) study. , 2010, Ophthalmology.

[148]  [Guideline-based planning for the treatment of diabetic retinopathy]. , 2010, Nihon rinsho. Japanese journal of clinical medicine.

[149]  R. Edwards,et al.  Diabetic retinopathy screening: a systematic review of the economic evidence , 2010, Diabetic medicine : a journal of the British Diabetic Association.

[150]  null Die redaktionellen Mitarbeiter sind am Ende des Be gelistet Stellungnahme der Deutschen Ophthalmologischen Gesellschaft, der Retinologischen Gesellschaft und des Berufsverbands der Augenärzte Deutschlands zur Therapie der diabetischen Makulopathie , 2011 .

[151]  E. Uchino,et al.  Comparative study of vitrectomy versus intravitreous triamcinolone for diabetic macular edema on randomized paired-eyes , 2011, Graefe's Archive for Clinical and Experimental Ophthalmology.

[152]  David S Friedman,et al.  Diabetic retinopathy in the developing world: how to approach identifying and treating underserved populations. , 2011, American journal of ophthalmology.

[153]  J. Harvey The influence of sex and puberty on the progression of diabetic nephropathy and retinopathy , 2011, Diabetologia.

[154]  Piya Hanvoravongchai,et al.  Human resources for health in southeast Asia: shortages, distributional challenges, and international trade in health services , 2011, The Lancet.

[155]  H. Taylor,et al.  Prevalence of self‐reported diabetes and diabetic retinopathy in indigenous Australians: the National Indigenous Eye Health Survey , 2011, Clinical & experimental ophthalmology.

[156]  H. Taylor,et al.  Diabetic retinopathy--screening and management by Australian GPs. , 2011, Australian family physician.

[157]  Jennifer K. Sun,et al.  Expanded 2-year follow-up of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. , 2011, Ophthalmology.

[158]  H. Hammes,et al.  Diabetic retinopathy in type 1 diabetes—a contemporary analysis of 8,784 patients , 2011, Diabetologia.

[159]  M. B. Sultan,et al.  A phase 2/3, multicenter, randomized, double-masked, 2-year trial of pegaptanib sodium for the treatment of diabetic macular edema. , 2011, Ophthalmology.

[160]  [Recommendation of the Retinological Society, the German Ophthalmological Society and the Professional Association of Ophthalmologists in Germany: treatment of diabetic maculopathy]. , 2011, Klinische Monatsblatter fur Augenheilkunde.

[161]  Planning diabetic retinopathy services — lessons from Latin America , 2011, Community eye health.

[162]  [Clinical practice guidelines. Diagnosis and treatment of diabetic retinopathy]. , 2011, Revista medica del Instituto Mexicano del Seguro Social.

[163]  Guía de práctica clínica. Diagnóstico y tratamiento de la retinopatía diabética , 2011 .

[164]  M. Ezzati,et al.  National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants , 2011, The Lancet.

[165]  Changing scenery of eye care in China: from cataract to diabetic retinopathy. , 2012, Archives of ophthalmology.

[166]  T. Peto,et al.  A 2-year prospective randomized controlled trial of intravitreal bevacizumab or laser therapy (BOLT) in the management of diabetic macular edema: 24-month data: report 3. , 2012, Archives of ophthalmology.

[167]  B. Klein,et al.  Global Prevalence and Major Risk Factors of Diabetic Retinopathy , 2012, Diabetes Care.

[168]  Diagnosis and treatment of diabetic retinopathy , 2013 .