Integrin-mediated targeting of drug delivery to irradiated tumor blood vessels.

[1]  Grietje Molema,et al.  Tumor Vascular Endothelium: Barrier or Target in Tumor Directed Drug Delivery and Immunotherapy , 2004, Pharmaceutical Research.

[2]  S. Fox,et al.  Markers of tumor angiogenesis: clinical applications in prognosis and anti-angiogenic therapy , 2004, Investigational New Drugs.

[3]  Hon J. Yu,et al.  A Longitudinal Study of Radiation-Induced Changes in Tumor Vasculature by Contrast-Enhanced Magnetic Resonance Imaging , 2002, Radiation research.

[4]  M. Bednarski,et al.  Tumor Regression by Targeted Gene Delivery to the Neovasculature , 2002, Science.

[5]  Ramon Planas,et al.  Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial , 2002, The Lancet.

[6]  J. Tímár,et al.  Multiple Roles for Platelet GPIIb/IIIa and αvβ3 Integrins in Tumor Growth, Angiogenesis, and Metastasis , 2002 .

[7]  D. Taverna,et al.  Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins , 2002, Nature Medicine.

[8]  W. Oyen,et al.  Radiopharmaceuticals to image infection and inflammation. , 2001, Seminars in nuclear medicine.

[9]  R. Kalluri,et al.  Extracellular Matrix-derived Peptide Binds to αvβ3 Integrin and Inhibits Angiogenesis* , 2001, The Journal of Biological Chemistry.

[10]  D. Hallahan,et al.  Targeting drug delivery to radiation-induced neoantigens in tumor microvasculature. , 2001, Journal of controlled release : official journal of the Controlled Release Society.

[11]  E F Donnelly,et al.  Quantified power Doppler US of tumor blood flow correlates with microscopic quantification of tumor blood vessels. , 2001, Radiology.

[12]  D. Hallahan,et al.  Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy. , 2001, Cancer research.

[13]  D. Boger,et al.  Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[14]  L. Steinman,et al.  ICAM-1 expression in autoimmune encephalitis visualized using magnetic resonance imaging , 2000, Journal of Neuroimmunology.

[15]  Erkki Ruoslahti,et al.  Anti-cancer activity of targeted pro-apoptotic peptides , 1999, Nature Medicine.

[16]  A. Plückthun,et al.  Beyond binding: using phage display to select for structure, folding and enzymatic activity in proteins. , 1999, Current opinion in structural biology.

[17]  D. Hallahan,et al.  Accumulation of P-selectin in the lumen of irradiated blood vessels. , 1999, Radiation research.

[18]  S. Seeber,et al.  Paclitaxel and UFT plus oral calcium folinate in pretreated metastatic breast cancer. , 1999, Oncology.

[19]  R Pasqualini,et al.  NG2 proteoglycan-binding peptides target tumor neovasculature. , 1999, Cancer research.

[20]  Erkki Ruoslahti,et al.  Membrane Dipeptidase Is the Receptor for a Lung-targeting Peptide Identified by in Vivo Phage Display* , 1999, The Journal of Biological Chemistry.

[21]  D. Hallahan,et al.  X-ray-induced P-selectin localization to the lumen of tumor blood vessels. , 1998, Cancer research.

[22]  M. Zwick,et al.  Phage-displayed peptide libraries. , 1998, Current opinion in biotechnology.

[23]  E. Ruoslahti,et al.  Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. , 1998, Science.

[24]  I. Pastan,et al.  Targeted therapy of cancer with recombinant immunotoxins. , 1997, Biochimica et biophysica acta.

[25]  Fung,et al.  Polymeric implants for cancer chemotherapy. , 1997, Advanced drug delivery reviews.

[26]  John W. Park,et al.  Sterically stabilized anti-HER2 immunoliposomes: design and targeting to human breast cancer cells in vitro. , 1997, Biochemistry.

[27]  D. Hallahan,et al.  Cell adhesion molecules mediate radiation-induced leukocyte adhesion to the vascular endothelium. , 1996, Cancer research.

[28]  Erkki Ruoslahti,et al.  Organ targeting In vivo using phage display peptide libraries , 1996, Nature.

[29]  E Ruoslahti,et al.  RGD and other recognition sequences for integrins. , 1996, Annual review of cell and developmental biology.

[30]  P. Trail,et al.  Immunoconjugates and immunotoxins for therapy of solid tumors , 1996, Cancer Chemotherapy and Pharmacology.

[31]  B. Beilin,et al.  Effect of oral chemotherapy on the mitochondrial size of mouse intestinal cells , 1996, Cancer Chemotherapy and Pharmacology.

[32]  J. Folkman.  Clinical Applications of Research on Angiogenesis , 1995 .

[33]  D. Hallahan,et al.  E-selectin gene induction by ionizing radiation is independent of cytokine induction. , 1995, Biochemical and biophysical research communications.

[34]  I. Kovesdi,et al.  Targeting of adenovirus penton base to new receptors through replacement of its RGD motif with other receptor-specific peptide motifs. , 1995, Gene therapy.

[35]  Samuel Hellman,et al.  Spatial and temporal control of gene therapy using ionizing radiation , 1995, Nature Medicine.

[36]  C. T. Baillie,et al.  Tumour vasculature--a potential therapeutic target. , 1995, British Journal of Cancer.

[37]  D. Cheresh,et al.  Integrin α v β 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels , 1994, Cell.

[38]  Y. Kan,et al.  Tissue-specific targeting of retroviral vectors through ligand-receptor interactions. , 1994, Science.

[39]  H. Fine,et al.  Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to ganciclovir. , 1994, Cancer research.

[40]  J. F. Atkins,et al.  Frameshifting in gene 10 of bacteriophage T7 , 1991, Journal of bacteriology.

[41]  M. Russel,et al.  Filnmentous phage assembly , 1991, Molecular microbiology.

[42]  H. Dvorak,et al.  Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodies. , 1991, Cancer cells.

[43]  H. Dvorak,et al.  Penetration of Tumor Tissue by Antibodies and Other Immunoproteins , 1991, Annals of the New York Academy of Sciences.

[44]  A. Brill,et al.  Preclinical assessments of 90Y-labeled C110 anti-carcinoembryonic antigen immunotoxin: a therapeutic immunoconjugate for human colon cancer. , 1991, Cancer research.

[45]  J W Smith,et al.  The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunit. , 1988, The Journal of biological chemistry.

[46]  S. Santoro,et al.  Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins , 1987, Cell.

[47]  J. Powers,et al.  Albumin microspheres as carrier of an inhibitor of leukocyte elastase: potential therapeutic agent for emphysema. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[48]  W. Kruskal,et al.  Use of Ranks in One-Criterion Variance Analysis , 1952 .