Preoperative diffusion tensor imaging: improving neurosurgical outcomes in brain tumor patients.

Preoperative mapping has revolutionized neurosurgical care for brain tumor patients. Maximizing resections has improved diagnosis, optimized treatment algorithms, and decreased potentially devastating postoperative deficits. Although mapping has multiple steps and complimentary localization sources, diffusion tensor imaging (DTI) excels in its essential role in depicting white matter tracts. A thorough understanding of DTI, data visualization methods, and limitations with mastery of functional and dysfunctional white matter anatomy is necessary to realize the potential of DTI. By establishing spatial relationships between lesion borders and functional networks preoperatively and intraoperatively, DTI is central to high-risk neurosurgical resections and becoming the standard of care.

[1]  D. Tuch Q‐ball imaging , 2004, Magnetic resonance in medicine.

[2]  R. C. Oldfield The assessment and analysis of handedness: the Edinburgh inventory. , 1971, Neuropsychologia.

[3]  F. Jolesz,et al.  Survival rates in patients with low‐grade glioma after intraoperative magnetic resonance image guidance , 2005, Cancer.

[4]  Srikantan S Nagarajan,et al.  Accuracy of diffusion tensor magnetic resonance imaging tractography assessed using intraoperative subcortical stimulation mapping and magnetic source imaging. , 2007, Journal of neurosurgery.

[5]  Andrew L. Alexander,et al.  Bootstrap white matter tractography (BOOT-TRAC) , 2005, NeuroImage.

[6]  Z L Gokaslan,et al.  A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. , 2001, Journal of neurosurgery.

[7]  L. Frank Characterization of anisotropy in high angular resolution diffusion‐weighted MRI , 2002, Magnetic resonance in medicine.

[8]  M. Mikhael,et al.  Supratentorial gliomas: surgical considerations and immediate postoperative results. Gross total resection versus partial resection. , 1987, Neurosurgery.

[9]  P. V. van Zijl,et al.  Three‐dimensional tracking of axonal projections in the brain by magnetic resonance imaging , 1999, Annals of neurology.

[10]  C. Price The anatomy of language: contributions from functional neuroimaging , 2000, Journal of anatomy.

[11]  M. Brell,et al.  Factors Influencing Surgical Complications of Intra-Axial Brain Tumours , 2000, Acta Neurochirurgica.

[12]  Wade M Mueller,et al.  The Role of Diffusion Tensor Imaging in Establishing the Proximity of Tumor Borders to Functional Brain Systems: Implications for Preoperative Risk Assessments and Postoperative Outcomes , 2004, Technology in cancer research & treatment.

[13]  S Pajevic,et al.  Color schemes to represent the orientation of anisotropic tissues from diffusion tensor data: Application to white matter fiber tract mapping in the human brain , 1999, Magnetic resonance in medicine.

[14]  A. Alexander,et al.  Diffusion tensor imaging of cerebral white matter: a pictorial review of physics, fiber tract anatomy, and tumor imaging patterns. , 2004, AJNR. American journal of neuroradiology.

[15]  Wade M Mueller,et al.  Lesion-induced Pseudo-dominance at Functional Magnetic Resonance Imaging: Implications for Preoperative Assessments , 2004, Neurosurgery.

[16]  P J Kelly,et al.  Resection, biopsy, and survival in malignant glial neoplasms. A retrospective study of clinical parameters, therapy, and outcome. , 1993, Journal of neurosurgery.

[17]  H. Thaler,et al.  Morbidity and mortality of craniotomy for excision of supratentorial gliomas , 1988, Neurology.

[18]  H. Moser,et al.  Imaging cortical association tracts in the human brain using diffusion‐tensor‐based axonal tracking , 2002, Magnetic resonance in medicine.

[19]  J. Pillai,et al.  The Evolution of Clinical Functional Imaging during the Past 2 Decades and Its Current Impact on Neurosurgical Planning , 2010, American Journal of Neuroradiology.

[20]  Wade M Mueller,et al.  Pseudo-reorganization of language cortical function at fMR imaging: a consequence of tumor-induced neurovascular uncoupling. , 2003, AJNR. American journal of neuroradiology.

[21]  M. Raichle,et al.  Tracking neuronal fiber pathways in the living human brain. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[22]  Chris A Clark,et al.  White matter fiber tracking in patients with space-occupying lesions of the brain: a new technique for neurosurgical planning? , 2003, NeuroImage.

[23]  A. Anderson Theoretical analysis of the effects of noise on diffusion tensor imaging , 2001, Magnetic resonance in medicine.

[24]  Susan M. Chang,et al.  Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[25]  Christine Delmaire,et al.  Comparison of diffusion tensor imaging tractography of language tracts and intraoperative subcortical stimulations. , 2010, Journal of neurosurgery.

[26]  J. Ulmer,et al.  White Matter: Functional Anatomy of Key Tracts , 2011 .

[27]  T. Schwartz,et al.  Tumor involvement of the corticospinal tract: diffusion magnetic resonance tractography with intraoperative correlation. , 2001, Journal of neurosurgery.

[28]  N. Hopf,et al.  Contribution of diffusion tensor imaging to delineation of gliomas and glioblastomas , 2004, Journal of magnetic resonance imaging : JMRI.

[29]  Ji Heon Hong,et al.  Location of the corticospinal tract at the corona radiata in human brain , 2010, Brain Research.

[30]  Ayse Aralasmak,et al.  Association, Commissural, and Projection Pathways and Their Functional Deficit Reported in Literature , 2006, Journal of computer assisted tomography.

[31]  M. Bernstein,et al.  Awake craniotomy with brain mapping as the routine surgical approach to treating patients with supratentorial intraaxial tumors: a prospective trial of 200 cases. , 1999, Journal of neurosurgery.

[32]  Ying Mao,et al.  CLINICAL EVALUATION AND FOLLOW‐UP OUTCOME OF DIFFUSION TENSOR IMAGING‐BASED FUNCTIONAL NEURONAVIGATION: A PROSPECTIVE, CONTROLLED STUDY IN PATIENTS WITH GLIOMAS INVOLVING PYRAMIDAL TRACTS , 2007, Neurosurgery.

[33]  M. Berger,et al.  Minimalism through intraoperative functional mapping. , 1996, Clinical neurosurgery.

[34]  Nathalie Tzourio-Mazoyer,et al.  New insights into the anatomo-functional connectivity of the semantic system: a study using cortico-subcortical electrostimulations. , 2005, Brain : a journal of neurology.

[35]  J. Helpern,et al.  Diffusional kurtosis imaging: The quantification of non‐gaussian water diffusion by means of magnetic resonance imaging , 2005, Magnetic resonance in medicine.

[36]  John L. Ulmer,et al.  DTI for Presurgical Mapping , 2014 .

[37]  Alan Connelly,et al.  Direct estimation of the fiber orientation density function from diffusion-weighted MRI data using spherical deconvolution , 2004, NeuroImage.

[38]  D. Pandya,et al.  Segmentation of subcomponents within the superior longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study. , 2005, Cerebral cortex.

[39]  D. Pandya,et al.  Fiber Pathways of the Brain , 2006 .

[40]  Geoffrey J M Parker,et al.  A framework for a streamline‐based probabilistic index of connectivity (PICo) using a structural interpretation of MRI diffusion measurements , 2003, Journal of magnetic resonance imaging : JMRI.

[41]  E. Wu,et al.  MR diffusion kurtosis imaging for neural tissue characterization , 2010, NMR in biomedicine.

[42]  D. Poeppel,et al.  Dorsal and ventral streams: a framework for understanding aspects of the functional anatomy of language , 2004, Cognition.

[43]  Tzu-Chao Chuang,et al.  PROPELLER EPI: An MRI technique suitable for diffusion tensor imaging at high field strength with reduced geometric distortions , 2005, Magnetic resonance in medicine.

[44]  Pratik Mukherjee,et al.  Diffusion-tensor imaging-guided tracking of fibers of the pyramidal tract combined with intraoperative cortical stimulation mapping in patients with gliomas. , 2004, Journal of neurosurgery.

[45]  Wei Huang,et al.  Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project. , 2003, Journal of neurosurgery.

[46]  J. Masdeu,et al.  Localization in Clinical Neurology , 1985 .

[47]  John L. Ulmer,et al.  Issues in Translating Imaging Technology and Presurgical Diffusion Tensor Imaging , 2011 .

[48]  G H Barnett,et al.  A proposed preoperative grading scheme to assess risk for surgical resection of primary and secondary intraaxial supratentorial brain tumors. , 1998, Neurosurgical focus.

[49]  Timothy C. Ryken,et al.  Surgical management of newly diagnosed glioblastoma in adults: role of cytoreductive surgery , 2008, Journal of Neuro-Oncology.

[50]  Manuel Lopes,et al.  Intraoperative mapping of the subcortical language pathways using direct stimulations. An anatomo-functional study. , 2002, Brain : a journal of neurology.

[51]  Veit Rohde,et al.  Intraoperative three-dimensional visualization of the pyramidal tract in a neuronavigation system (PTV) reliably predicts true position of principal motor pathways. , 2003, Surgical neurology.

[52]  K R Hess,et al.  Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors. , 1998, Neurosurgery.

[53]  P. Hagmann,et al.  Mapping complex tissue architecture with diffusion spectrum magnetic resonance imaging , 2005, Magnetic resonance in medicine.

[54]  Derek K. Jones,et al.  Virtual in Vivo Interactive Dissection of White Matter Fasciculi in the Human Brain , 2002, NeuroImage.

[55]  J. Ulmer,et al.  Functional neuroradiology: Principles and clinical applications , 2012 .

[56]  P. Basser,et al.  In vivo fiber tractography using DT‐MRI data , 2000, Magnetic resonance in medicine.

[57]  Mitchel S Berger,et al.  Functional outcome after language mapping for glioma resection. , 2008, The New England journal of medicine.

[58]  Donald W. Kormos,et al.  Glioma Resection in a Shared-resource Magnetic Resonance Operating Room after Optimal Image-guided Frameless Stereotactic Resection , 2001, Neurosurgery.

[59]  F. Zanella,et al.  Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. , 2006, The Lancet. Oncology.