The successful use of minocycline in pyoderma gangrenosum—a report of seven cases and review of the literature

We report seven cases in which minocycline was successfully used to treat pyoderma gangrenosum. This more than doubles the six previously reported cases. Minocycline is considerably safer than systemic steroids and may, therefore, represent a useful advance in the treatment of this disease.

[1]  J. Bonnetblanc,et al.  [Pyoderma gangrenosum and vasculitis. Pathogenic discussion apropos of 3 cases]. , 1987, Annales de dermatologie et de venereologie.

[2]  F. Goldstein,et al.  Intralesional steroid therapy of pyoderma gangrenosum. , 1985, Journal of clinical gastroenterology.

[3]  C. Vickers,et al.  Pyoderma gangrenosum treated with cyclosporin A , 1985, The British journal of dermatology.

[4]  R. S. Basler Minocycline-related hyperpigmentation. , 1985, Archives of dermatology.

[5]  F. Malkinson,et al.  Pyoderma Gangrenosum: Response to Cyclophosphamide Therapy , 1983 .

[6]  M. Davies,et al.  Pyoderma gangrenosum: successful treatment with minocycline , 1981, Clinical and experimental dermatology.

[7]  Walters,et al.  Tetracycline and benign intracranial hypertension: report of five cases. , 1981, British medical journal.

[8]  G. Nuki,et al.  Pyoderma Gangrenosum: CLINICAL AND LABORATORY FINDINGS IN 15 PATIENTS WITH SPECIAL REFERENCE TO POLYARTHRITIS , 1980, Medicine.

[9]  P. Holt The current status of pyoderma gangrenosum , 1979, Clinical and experimental dermatology.

[10]  Bergfeld Wf,et al.  Pyoderma gangrenosum responsive to minocycline hydrochloride. , 1978 .

[11]  L. Hovelius,et al.  Report of Five Cases , 1977 .

[12]  H. Valdimarsson,et al.  (33) Pyoderma gangrenosum with cellular immunity deficit treated with plasmaphoresis and leukocyte transfusion , 1976, British Journal of Dermatology.

[13]  D. Rosenthal,et al.  Pyoderma Gangrenosum and rheumatoid arthritis. , 1975, Archives of dermatology.

[14]  Dantzig Pi Letter: Pyoderma gangrenosum. , 1975 .

[15]  R. Couch,et al.  Effects of tetracycline on leukotaxis. , 1974, The Journal of infectious diseases.

[16]  E. Schöpf,et al.  [Azathioprine treatment of ulcerative dermatitis (pyoderma gangrenosum)]. , 1969, Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete.

[17]  I. Sluis Two Cases of Pyoderma (Ecthyma) Gangraenosum Associated with the Presence of an Abnormal Serumprotein (β2A-paraprotein) , 1966 .

[18]  A. Lorincz,et al.  Sulfapyridine and sulfone type drugs in dermatology. , 1962, Archives of dermatology.

[19]  G. Percival PYODERMA GANGRENOSUM: THE HISTOLOGY OF THE PRIMARY LESION. * , 1957, The British journal of dermatology.

[20]  H. Perry,et al.  Pyoderma Gangrenosum: A Clinical Study of Nineteen Cases , 1957 .

[21]  B. Russell PHAGEDENIC AND GANGRENOUS ULCERATION OF THE SKIN COMPLICATING ULCERATIVE COLITIS (PHAGEDENA GEOMETRICUM) , 1950 .

[22]  F. Sagher,et al.  PHAGEDENIC ULCER (PYODERMA GANGRAENOSUM): TREATMENT WITH SULFAPYRIDINE POWDER AND MOIST CHAMBER THERAPY , 1943 .

[23]  S. S. Greenbaum PHAGEDAENA GEOMETRICA (BROCQ): INOCULATION STUDIES WITH VIABLE BACTERIA CULTURED FROM LESIONS OF PHAGEDAENA GEOMETRICA (BROCQ) (CHRONIC BURROWING ULCER AND PYODERMA GANGRAENOSUM) , 1941 .

[24]  A. L. Weiner PYODERMA GANGRAENOSUM TREATED WITH SULFANILAMIDE: REPORT OF A CASE , 1940 .

[25]  L. Brunsting,et al.  PYODERMA (ECHTHYMA) GANGRENOSUM: CLINICAL AND EXPERIMENTAL OBSERVATIONS IN FIVE CASES OCCURRING IN ADULTS , 1930 .