Novel Reassortant Highly Pathogenic Avian Influenza (H5N5) Viruses in Domestic Ducks, China

In China, domestic ducks and wild birds often share the same water, in which influenza viruses replicate preferentially. Isolation of 2 novel reassortant highly pathogenic avian influenza (H5N5) viruses from apparently healthy domestic ducks highlights the role of these ducks as reassortment vessels. Such new subtypes of influenza viruses may pose a pandemic threat.

[1]  W. J. Bean,et al.  Evolution and ecology of influenza A viruses , 1992, Microbiological reviews.

[2]  Michael W. Shaw,et al.  Molecular Correlates of Influenza A H5N1 Virus Pathogenesis in Mice , 2000, Journal of Virology.

[3]  Y. Guan,et al.  Role of domestic ducks in the propagation and biological evolution of highly pathogenic H5N1 influenza viruses in Asia. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[4]  Y. Guan,et al.  Avian flu: H5N1 virus outbreak in migratory waterfowl , 2005, Nature.

[5]  Gavin J. D. Smith,et al.  Emergence and predominance of an H5N1 influenza variant in China , 2006, Proceedings of the National Academy of Sciences.

[6]  Wenbo Liu,et al.  Characterization of H9N2 influenza viruses isolated from vaccinated flocks in an integrated broiler chicken operation in eastern China during a 5 year period (1998-2002). , 2008, The Journal of general virology.

[7]  Oie,et al.  Toward a Unified Nomenclature System for Highly Pathogenic Avian Influenza Virus (H5N1) , 2008, Emerging infectious diseases.

[8]  Gavin J. D. Smith,et al.  Characterization of Avian Influenza Viruses A (H5N1) from Wild Birds, Hong Kong, 2004–2008 , 2009, Emerging infectious diseases.

[9]  R. Webster,et al.  Changes in H5N1 influenza virus hemagglutinin receptor binding domain affect systemic spread , 2009, Proceedings of the National Academy of Sciences.

[10]  R. Webster,et al.  Ducks: The “Trojan Horses” of H5N1 influenza , 2009, Influenza and other respiratory viruses.

[11]  J. Oem,et al.  Short Communication Characterization of H5N2 influenza viruses isolated in South Korea and their influence on the emergence of a novel H9N2 influenza virus , 2010 .

[12]  T. Yamashiro,et al.  Possible circulation of H5N1 avian influenza viruses in healthy ducks on farms in northern Vietnam , 2010, Microbiology and immunology.

[13]  Gavin J. D. Smith,et al.  Establishment of an H6N2 Influenza Virus Lineage in Domestic Ducks in Southern China , 2010, Journal of Virology.