The γδT Cell Receptor

[1]  A. Korman,et al.  Predominant variable region gene usage by gamma/delta T cell receptor- bearing cells in the adult thymus , 1988, The Journal of experimental medicine.

[2]  J. Coligan,et al.  Thymus-dependent and thymus-independent developmental pathways for peripheral T cell receptor-gamma delta-bearing lymphocytes. , 1988, Journal of immunology.

[3]  J. Mclean,et al.  Extensive junctional diversity of rearranged human T cell receptor delta genes. , 1988, Science.

[4]  M. Cooper,et al.  Identification of the avian homologues of mammalian CD4 and CD8 antigens. , 1988, Journal of immunology.

[5]  M. Lefranc,et al.  Variable region genes in the human T‐cell rearranging gamma (TRG) locus: V‐J junction and homology with the mouse genes. , 1988, The EMBO journal.

[6]  W. Paul,et al.  Proliferation and production of IL-2 and B cell stimulatory factor 1/IL-4 in early fetal thymocytes by activation through Thy-1 and CD3. , 1988, Journal of immunology.

[7]  T. Rabbitts,et al.  The mechanism of chromosomal translocation t(11;14) involving the T‐cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15. , 1988, The EMBO journal.

[8]  M. Cooper,et al.  A large subpopulation of avian T cells express a homologue of the mammalian T gamma/delta receptor , 1988, The Journal of experimental medicine.

[9]  Mark M. Davis,et al.  T-cell receptor δ gene rearrangements in early thymocytes , 1987, Nature.

[10]  J. Freed,et al.  Peptide sequences of T-cell receptor δ and γ chains are identical to predicted X and γ proteins , 1987, Nature.

[11]  Mark M. Davis,et al.  Identification and sequence of a fourth human T cell antigen receptor chain , 1987, Nature.

[12]  G. Pantaleo,et al.  Analysis of signal transducing mechanisms in CD3+ CD4- CD8- cells expressing the putative T cell receptor gamma gene product. , 1987, Journal of immunology.

[13]  T. Waldmann,et al.  Deletional rearrangement in the human T-cell receptor alpha-chain locus. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[14]  M. Lefranc,et al.  Rearrangements to the JP1, JP and JP2 segments in the human T‐cell rearranging gamma gene (TRGγ) locus , 1987, FEBS letters.

[15]  J. Bluestone,et al.  Major histocompatibility complex-linked specificity of γδ receptor-bearing T lymphocytes , 1987, Nature.

[16]  L. Lanier,et al.  Evidence that the T cell antigen receptor may not be involved in cytotoxicity mediated by gamma/delta and alpha/beta thymic cell lines , 1987, The Journal of experimental medicine.

[17]  M. Krangel,et al.  Identification of putative human T cell receptor delta complementary DNA clones. , 1987, Science.

[18]  J. Mclean,et al.  Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit. , 1987, Science.

[19]  M. A. Saper,et al.  The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens , 1987, Nature.

[20]  M. A. Saper,et al.  Structure of the human class I histocompatibility antigen, HLA-A2 , 1987, Nature.

[21]  M. Lipinski,et al.  Brief Definitive Report A NOVEL SUBSET OF HUMAN LYMPHOCYTES WITH A T CELL RECEPTOR-7 COMPLEX , 2003 .

[22]  M. Bevan,et al.  Differentiation potential of subsets of CD4−8− thymocytes , 1987, Nature.

[23]  J. Coligan,et al.  A novel population of T-cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ gene family , 1987, Nature.

[24]  J. Seidman,et al.  Measuring the human T cell receptor gamma-chain locus. , 1987, Science.

[25]  S. Tonegawa,et al.  Expression of the T-cell receptor gamma-chain gene products on the surface of peripheral T cells and T-cell blasts generated by allogeneic mixed lymphocyte reaction. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[26]  Y. Chien,et al.  Transient rearrangements of the T cell antigen receptor alpha locus in early thymocytes , 1987, The Journal of experimental medicine.

[27]  P. Pelicci,et al.  Molecular diversity of the human T-gamma constant region genes. , 1987, Science.

[28]  R. Warnke,et al.  Immunophenotypic criteria for the diagnosis of non-Hodgkin's lymphoma. , 1987, The American journal of pathology.

[29]  H. Willard,et al.  Human T‐cell tumours containing chromosome 14 inversion or translocation with breakpoints proximal to immunoglobulin joining regions at 14q32. , 1987, The EMBO journal.

[30]  J. Coligan,et al.  Independent association of T cell receptor beta and gamma chains with CD3 in the same cell , 1987, The Journal of experimental medicine.

[31]  J. Allison,et al.  Regulation of T-cell receptor γ-chain RNA expression in murine Thy-1+ dendritic epidermal cells , 1987, Nature.

[32]  J. Mclean,et al.  Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes. , 1987, Science.

[33]  P. Nowell,et al.  Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[34]  J. Coligan,et al.  Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[35]  J. Pelkonen,et al.  A new mouse TCR V gamma gene that shows remarkable evolutionary conservation. , 1987, The EMBO journal.

[36]  M. Lefranc,et al.  New subgroups in the human T cell rearranging V gamma gene locus. , 1987, The EMBO journal.

[37]  R. Sékaly,et al.  Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery , 1987, The Journal of experimental medicine.

[38]  J. Mclean,et al.  T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[39]  F. Fox,et al.  Identification of a second T-cell antigen receptor in human and mouse by an anti-peptide gamma-chain-specific monoclonal antibody. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[40]  B. Alarcón,et al.  The T-cell receptor gamma chain-CD3 complex: implication in the cytotoxic activity of a CD3+ CD4- CD8- human natural killer clone. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[41]  Mark M. Davis,et al.  A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation , 1987, Nature.

[42]  H. Yamagishi,et al.  Isolation of an excision product of T-cell receptor α-chain gene rearrangments , 1987, Nature.

[43]  J. Coligan,et al.  Identification of a T3-associated gamma delta T cell receptor on Thy-1+ dendritic epidermal Cell lines. , 1987, Science.

[44]  L. Degos,et al.  Human T cell clones use a CD3-associated surface antigen recognition structure to exhibit both NK-like and allogeneic cytotoxic reactivity. , 1987, Journal of Immunology.

[45]  J. Seidman,et al.  Functional gamma chain-associated T cell receptors on cerebrospinal fluid-derived natural killer-like T cell clones , 1987, The Journal of experimental medicine.

[46]  Laurie Smith.  CD4+ murine T cells develop from CD8+ precursors in vivo , 1987, Nature.

[47]  J. Seidman,et al.  Human T cell gamma chain joining regions and T cell development. , 1987, Journal of immunology.

[48]  E. Tschachler,et al.  Thy-1+ dendritic epidermal cells belong to the T-cell lineage. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[49]  N. Federspiel,et al.  The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8- T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer , 1987, The Journal of experimental medicine.

[50]  B. V. van Krimpen,et al.  Lysis of tumor cells by CD3+4-8-16+ T cell receptor alpha beta- clones, regulated via CD3 and CD16 activation sites, recombinant interleukin 2, and interferon beta 1. , 1987, Journal of immunology.

[51]  R. Warnke,et al.  Characterization and expression of the human alpha beta T cell receptor by using a framework monoclonal antibody. , 1987, Journal of immunology.

[52]  J. Bluestone,et al.  Identification of a monoclonal antibody specific for a murine T3 polypeptide. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[53]  J. Seidman,et al.  Characterization of an expressed CDS-associated Ti γ-chain reveals Cγ domain polymorphism , 1987, Nature.

[54]  J. Bluestone,et al.  Characterization of murine thymocytes with CDS-associated T-cell receptor structures , 1987, Nature.

[55]  J. Coligan,et al.  Differential expression of two distinct T-cell receptors during thymocyte development , 1987, Nature.

[56]  F. Faure,et al.  A γ-chain complex forms a functional receptor on cloned human lymphocytes with natural killer-like activity , 1987, Nature.

[57]  J. Seidman,et al.  Two forms of the T-cell receptor γ protein found on peripheral blood cytotoxic T lymphocytes , 1987, Nature.

[58]  J. Seidman,et al.  A T-cell receptor γ/CD3 complex found on cloned functional lymphocytes , 1987, Nature.

[59]  S. Tonegawa,et al.  Tγ protein is expressed on murine fetal thymocytes as a disulphide-linked heterodimer , 1987, Nature.

[60]  J. V. van Dongen,et al.  T cell receptor-CD3 complex during early T cell differentiation. Analysis of immature T cell acute lymphoblastic leukemias (T-ALL) at DNA, RNA, and cell membrane level. , 1987, Journal of immunology.

[61]  O. Acuto,et al.  T-cell antigen receptor expression in the thymus. , 1987, Human immunology.

[62]  G. Pantaleo,et al.  CD3+ WT31− peripheral T lymphocytes lack T44 (CD28), a surface molecule involved in activation of T cells bearing the α/β heterodimer , 1987 .

[63]  H. Macdonald,et al.  Anti‐Thy‐1‐induced proliferation of immature thymocytes expressing the CD3‐associated γ/δ heterodimer , 1987 .

[64]  E. Ciccone,et al.  Human CD3+4−8−WT31−T lymphocyte expressing the putative T cell receptor γ‐gene product. A limiting dilution and clonal analysis , 1987 .

[65]  H. Griesser,et al.  Repertoire of the human T cell gamma genes: high frequency of nonfunctional transcripts in thymus and mature T cells , 1987, European journal of immunology.

[66]  J. Seidman,et al.  Two types of gamma T cell receptors expressed by T cell acute lymphoblastic leukemias , 1987, European journal of immunology.

[67]  I. Weissman,et al.  Early events in T-cell maturation. , 1987, Annual review of immunology.

[68]  T. Mak,et al.  Genes of the T-cell antigen receptor in normal and malignant T cells. , 1987, Annual review of immunology.

[69]  J. Allison,et al.  Delta is the C x-gene product in the γ/δ antigen receptor of dendritic epidermal cells , 1987, Nature.

[70]  F. Sigaux,et al.  A t(8;14)(q24;q11) translocation in a T‐cell leukemia (L1‐all) with c‐myc and TcR‐alpha chain locus rearrangements , 1986, International journal of cancer.

[71]  J. Coligan,et al.  Characterization of T cell receptor gamma chain expression in a subset of murine thymocytes. , 1986, Science.

[72]  M. Lefranc,et al.  Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[73]  J. Rowley,et al.  T-cell receptor alpha-chain gene is split in a human T-cell leukemia cell line with a t(11;14)(p15;q11). , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[74]  T. Mak,et al.  Athymic mice express a high level of functional γ-chain but greatly reduced levels of α- and β-chain T-cell receptor messages , 1986, Nature.

[75]  F. Alt,et al.  A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes , 1986, Nature.

[76]  C. Croce,et al.  A common mechanism of chromosomal translocation in T- and B-cell neoplasia. , 1986, Science.

[77]  L. Lanier,et al.  Presence of Ti (WT31) negative T lymphocytes in normal blood and thymus , 1986, Nature.

[78]  J. C. Pratt,et al.  Direct evidence for the existence of nominal antigen binding sites on T cell surface Ti α-β heterodimers of MHC-restricted T cell clones , 1986, Cell.

[79]  P. Marrack,et al.  Synchronized rearrangement of T-cell gamma and beta chain genes in fetal thymocyte development. , 1986, Science.

[80]  F. Faure,et al.  A unique T-cell receptor complex expressed on human fetal lymphocytes displaying natural-killer-like activity , 1986, Nature.

[81]  A. Weiss,et al.  Expression of T3 in association with a molecule distinct from the T-cell antigen receptor heterodimer. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[82]  J. Rowley,et al.  Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor alpha-chain gene and sequences on the 3' side of MYC. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[83]  T. Honjo,et al.  Expression and rearrangement of the alpha, beta, and gamma chain genes of the T cell receptor in cloned murine large granular lymphocyte lines. No correlation with the cytotoxic spectrum , 1986, The Journal of experimental medicine.

[84]  J. Seidman,et al.  Human T-cell γ genes contain N segments and have marked junctional variability , 1986, Nature.

[85]  J. Seidman,et al.  Identification of a putative second T-cell receptor , 1986, Nature.

[86]  D. Gold,et al.  Developmentally regulated rearrangement and expression of genes encoding the T cell receptor-T3 complex , 1986, Cell.

[87]  F. Oliveri,et al.  Normal T cell development is possible without ‘functional’ gamma chain genes. , 1986, The EMBO journal.

[88]  J. Crawford,et al.  Thy-1+ epidermal cells are not demonstrable in rat and human skin. , 1986, The Journal of investigative dermatology.

[89]  L. Lanier,et al.  Human CD3+ T lymphocytes that express neither CD4 nor CD8 antigens , 1986, The Journal of experimental medicine.

[90]  M. Cooper,et al.  Identification of a T3/T cell receptor complex in chickens , 1986, The Journal of experimental medicine.

[91]  L. Hood,et al.  Rearrangement and expression of T cell antigen receptor and gamma genes during thymic development , 1986, The Journal of experimental medicine.

[92]  P. Doherty,et al.  Diversity, rearrangement, and expression of murine T cell gamma genes , 1986, Cell.

[93]  R. Bell.  Protein kinase C activation by diacylglycerol second messengers , 1986, Cell.

[94]  E. Unanue,et al.  Antigenic competition at the level of peptide-Ia binding. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[95]  J. Freed,et al.  Interaction between a "processed" ovalbumin peptide and Ia molecules. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[96]  M. Minden,et al.  Rearrangement and expression of the alpha, beta, and gamma chain T cell receptor genes in human thymic leukemia cells and functional T cells , 1986, The Journal of experimental medicine.

[97]  P. Nowell,et al.  Deregulation of c-myc by translocation of the alpha-locus of the T-cell receptor in T-cell leukemias. , 1986, Science.

[98]  J. Rowley,et al.  Gene encoding the alpha chain of the T-cell receptor is moved immediately downstream of c-myc in a chromosomal 8;14 translocation in a cell line from a human T-cell leukemia. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[99]  H. Pircher,et al.  T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes , 1986, The Journal of experimental medicine.

[100]  M. Lefranc,et al.  Diversity and rearrangement of the human T cell rearranging γ genes: Nine germ-line variable genes belonging to two subgroups , 1986, Cell.

[101]  R. Tigelaar,et al.  Thy-1+ epidermal cells proliferate in response to concanavalin A and interleukin 2. , 1986, Journal of immunology.

[102]  C. Denny,et al.  A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci , 1986, Nature.

[103]  J. Seidman,et al.  Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[104]  E. Reinherz,et al.  Expression of the NKTa clonotype in a series of human natural killer clones with identical cytotoxic specificity , 1986, The Journal of experimental medicine.

[105]  M. Lefranc,et al.  Rearrangement of two distinct T-cell γ-chain variable-region genes in human DNA , 1986, Nature.

[106]  J. Seidman,et al.  Human T-cell gamma chain genes: organization, diversity, and rearrangement. , 1986, Science.

[107]  L. Hood,et al.  The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition. , 1986, Annual review of immunology.

[108]  P. Marrack,et al.  The antigen-specific, major histocompatibility complex-restricted receptor on T cells. , 1986, Advances in immunology.

[109]  R. Zinkernagel,et al.  No functional γ-chain transcripts detected in an alloreactive cytotoxic T-cell clone , 1986, Nature.

[110]  S. Tonegawa,et al.  A functional γ gene formed from known γ-gene segments is not necessary for antigen-specific responses of murine cytotoxic T lymphocytes , 1986, Nature.

[111]  S. Tonegawa,et al.  Diversity of murine gamma genes and expression in fetal and adult T lymphocytes , 1986, Nature.

[112]  K. Chen,et al.  Fusion of an immunoglobulin variable gene and a T cell receptor constant gene in the chromosome 14 inversion associated with T cell tumors , 1985, Cell.

[113]  R. Berger,et al.  Molecular cloning of a DNA fragment from human chromosome 14(14q11) involved in T‐cell malignancies. , 1985, The EMBO journal.

[114]  T. Mak,et al.  Organization and sequences of the diversity, joining, and constant region genes of the human T-cell receptor beta chain. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[115]  M. Crumpton,et al.  Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[116]  A. Palini,et al.  Fluorescence microscopic and flow cytometric analysis of bone marrow-derived cells in human epidermis: a search for the human analogue of the murine dendritic Thy-1+ epidermal cell. , 1985, The Journal of investigative dermatology.

[117]  M. Minden,et al.  Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor α-chain , 1985, Nature.

[118]  E. Rothenberg,et al.  Differentiation and cell division in the mammalian thymus. , 1985, Developmental biology.

[119]  M. Minden,et al.  Breakpoints in the human T-cell antigen receptor α-chain locus in two T-cell leukaemia patients with chromosomal translocations , 1985, Nature.

[120]  S. Tonegawa,et al.  The molecules of the immune system. , 1985, Scientific American.

[121]  S. Tonegawa,et al.  Expression of the T-cell-specific γ gene is unnecessary in T cells recognizing class II MHC determinants , 1985, Nature.

[122]  J. Borst,et al.  Characteristics of a monoclonal antibody (WT-31) that recognizes a common epitope on the human T cell receptor for antigen. , 1985, Journal of immunology.

[123]  B. Fowlkes,et al.  Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells , 1985, The Journal of experimental medicine.

[124]  E. Reinherz,et al.  Genes encoding the T-cell receptor alpha and beta subunits are transcribed in an ordered manner during intrathymic ontogeny. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[125]  T. Waldmann,et al.  Human γ-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7 , 1985, Nature.

[126]  M. Lefranc,et al.  Two tandemly organized human genes encoding the T-cell γ constant-region sequences show multiple rearrangement in different T-cell types , 1985, Nature.

[127]  S. Burakoff,et al.  T3 monoclonal antibody activation of nonspecific cytolysis: a mechanism of CTL inhibition. , 1985, Journal of immunology.

[128]  S. Tonegawa,et al.  Regulation of T-cell receptor gene expression in human T-cell development. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[129]  E. Reinherz,et al.  Analysis of T-cell receptor gene rearrangement and expression in human natural killer clones. , 1985, Science.

[130]  I. Trowbridge,et al.  Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor β-chain gene , 1985, Nature.

[131]  B. Fowlkes,et al.  Intrathymic differentiation: Thymocyte heterogeneity and the characterization of early t-cell precursors , 1985, Survey of immunologic research.

[132]  H. Spits,et al.  Induction of nonspecific cytotoxicity by monoclonal anti-T3 antibodies. , 1985, Journal of immunology.

[133]  M. Lefranc,et al.  The chromosomal location of T‐cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia. , 1985, The EMBO journal.

[134]  R. Steinman,et al.  The Thy-1-bearing cell of murine epidermis. A distinctive leukocyte perhaps related to natural killer cells , 1985, The Journal of experimental medicine.

[135]  H. Snodgrass,et al.  Expression of T-cell antigen receptor genes during fetal development in the thymus , 1985, Nature.

[136]  R. Axel,et al.  A one and a half receptor model for MHC-restricted antigen recognition by T lymphocytes , 1985, Cell.

[137]  J. Yagüe,et al.  Rearrangement of T-cell receptor beta-chain genes during T-cell development. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[138]  T. Mak,et al.  T cell receptor alpha chain genes are located on chromosome 14 at 14q11- 14q12 in humans , 1985, The Journal of experimental medicine.

[139]  L. Hood,et al.  Gene rearrangement in cells with natural killer activity and expression of the β-chain of the T-cell antigen receptor , 1985, Nature.

[140]  J. Allison,et al.  Identification of antigen receptor-associated structures on murine T cells , 1985, Nature.

[141]  S. Tonegawa,et al.  Developmental regulation of T-cell receptor gene expression , 1985, Nature.

[142]  L. Cantley,et al.  Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx , 1985, Cell.

[143]  A. Palumbo,et al.  Gene for alpha-chain of human T-cell receptor: location on chromosome 14 region involved in T-cell neoplasms. , 1985, Science.

[144]  J. Imboden,et al.  Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores , 1985, The Journal of experimental medicine.

[145]  R. Steinman,et al.  Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro , 1985, The Journal of experimental medicine.

[146]  S. Tonegawa,et al.  Chromosomal locations of the murine T-cell receptor alpha-chain gene and the T-cell gamma gene. , 1985, Science.

[147]  H. Snodgrass,et al.  Ontogeny of the T-cell antigen receptor within the thymus , 1985, Nature.

[148]  S. Tonegawa,et al.  Structure, organization, and somatic rearrangement of T cell gamma genes , 1985, Cell.

[149]  J. Strominger,et al.  Cross-linking of human T cell receptor proteins: association between the T cell idiotype β subunit and the T3 glycoprotein heavy subunit , 1985, Cell.

[150]  J. Woody,et al.  Partial primary structure of the alpha and beta chains of human tumor T-cell receptors. , 1985, Science.

[151]  O. Stutman.  Ontogeny of T Cells , 1985, Clinics in Immunology and Allergy.

[152]  J. D. de Vries,et al.  Antigen‐specific cytotoxic T cell and antigen‐specific proliferating T cell clones can be induced to cytolytic activity by monoclonal antibodies against T3 , 1985, European journal of immunology.

[153]  J. Lamb,et al.  Investigation of early T cell activation: Analysis of the effect of specific antigen, interleukin 2 and monoclonal antibodies on intracellular free calcium concentration , 1985, European journal of immunology.

[154]  A. Pierrès,et al.  Analysis of the Thy‐1 pathway of T cell hybridoma activation using 17 rat monoclonal antibodies reactive with distinct Thy‐1 epitopes , 1985, European journal of immunology.

[155]  H. Macdonald,et al.  Production and characterization of monoclonal anti‐Thy‐1 antibodies that stimulate lymphokine production by cytolytic T cell clones , 1985, European journal of immunology.

[156]  E. Unanue,et al.  Binding of immunogenic peptides to Ia histocompatibility molecules , 1985, Nature.

[157]  S. Tonegawa,et al.  Limited diversity of the rearranged T-cell γ gene , 1985, Nature.

[158]  F. Hecht,et al.  Common region on chromosome 14 in T-cell leukemia and lymphoma. , 1984, Science.

[159]  E. Reinherz,et al.  Genes encoding the Ti β subunit of the antigen/MHC receptor undergo rearrangement during intrathymic ontogeny prior to surface T3-Ti expression , 1984, Cell.

[160]  B. Fowlkes,et al.  Cell Surface Antigen Expression on Thymocytes: Development and Phenotypic Differentiation of Intrathymic Subsets , 1984, Immunological reviews.

[161]  K. Shortman,et al.  T Cell Development in the Adult Murine Thymus: Changes in the Expression of the Surface Antigens Ly2, L3T4 and B2A2 during Development from Early Precursor Cells to Emigrants , 1984, Immunological reviews.

[162]  Michael J. Berridge,et al.  Inositol trisphosphate, a novel second messenger in cellular signal transduction , 1984, Nature.

[163]  E. Reinherz,et al.  Homology of Ti α-subunit of a T-cell antigen–MHC receptor with immunoglobulin , 1984, Nature.

[164]  E. Reinherz,et al.  Calcium dependency of antigen-specific (T3-Ti) and alternative (T11) pathways of human T-cell activation. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[165]  A. Weiss,et al.  Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line , 1984, The Journal of experimental medicine.

[166]  J. Freed,et al.  Immunoglobulin-like nature of the α-chain of a human T-cell antigen/MHC receptor , 1984, Nature.

[167]  Mark M. Davis,et al.  A third type of murine T-cell receptor gene , 1984, Nature.

[168]  S. Tonegawa,et al.  A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes , 1984, Nature.

[169]  H. Oettgen,et al.  Characterization of the two heavy chains of the T3 complex on the surface of human T lymphocytes. , 1984, The Journal of biological chemistry.

[170]  Y. Nishizuka.  Turnover of inositol phospholipids and signal transduction. , 1984, Science.

[171]  P. Marrack,et al.  The major histocompatibility complex-restricted antigen receptor on T cells: Distribution on thymus and peripheral T cells , 1984, Cell.

[172]  J. Streilein,et al.  Thy-1 antigen-bearing dendritic cells in murine epidermis are derived from bone marrow precursors. , 1984, The Journal of investigative dermatology.

[173]  A. Weiss,et al.  Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[174]  S. Katz,et al.  Thy-1+ dendritic cells in murine epidermis are bone marrow-derived. , 1984, The Journal of investigative dermatology.

[175]  E. Reinherz,et al.  Purification and NH2-terminal amino acid sequencing of the beta subunit of a human T-cell antigen receptor. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[176]  J. Winter,et al.  Cytogenetic studies on patients with chronic T cell leukemia/lymphoma. , 1984, Blood.

[177]  A. Rao,et al.  Binding of antigen in the absence of histocompatibility proteins by arsonate-reactive T-cell clones , 1984, Cell.

[178]  E. Reinherz,et al.  An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein , 1984, Cell.

[179]  Mark M. Davis,et al.  Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins , 1984, Nature.

[180]  Mark M. Davis,et al.  Isolation of cDNA clones encoding T cell-specific membrane-associated proteins , 1984, Nature.

[181]  Tak W. Mak,et al.  A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains , 1984, Nature.

[182]  E. Shevach,et al.  T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4 , 1984, The Journal of experimental medicine.

[183]  A. Look,et al.  New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia , 1984, Cell.

[184]  P. Marrack,et al.  The major histocompatibility complex-restricted antigen receptor on T cells. , 1984, Annual review of immunology.

[185]  J. Yagüe,et al.  Primary structure of human T-cell receptor α-chain , 1984, Nature.

[186]  S. Orkin,et al.  Isolation of cDNA clones encoding the 20K T3 glycoprotein of human T-cell receptor complex , 1984, Nature.

[187]  L. Zech,et al.  Inversion of chromosome 14 marks human T-cell chronic lymphocytic leukaemia , 1984, Nature.

[188]  B. Haynes,et al.  Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[189]  S. Tonegawa,et al.  Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences , 1984, Nature.

[190]  T. Honjo,et al.  The D-JH complex is an intermediate to the complete immunoglobulin heavy-chain V-region gene. , 1983, Nucleic acids research.

[191]  P. Marrack,et al.  The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: Identification of constant and variable peptides , 1983, Cell.

[192]  R. Germain,et al.  Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[193]  H. Macdonald,et al.  Precursors of T cell growth factor producing cells in the thymus: ontogeny, frequency, and quantitative recovery in a subpopulation of phenotypically mature thymocytes defined by monoclonal antibody GK-1.5 , 1983, The Journal of experimental medicine.

[194]  E. Reinherz,et al.  Identification of a clonally restricted 90 kD heterodimer on two human cloned natural killer cell lines. Its role in cytotoxic effector function , 1983, The Journal of experimental medicine.

[195]  M. Crumpton,et al.  Biosynthesis and molecular nature of the T3 antigen of human T lymphocytes. , 1983, The EMBO journal.

[196]  J. Allison,et al.  The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by Xenoantiserum , 1983, Cell.

[197]  Peptide variability exists within alpha and beta subunits of the T cell receptor for antigen , 1983, The Journal of experimental medicine.

[198]  J. Dees,et al.  Thy-1 antigen-bearing dendritic cells populate murine epidermis. , 1983, The Journal of investigative dermatology.

[199]  K. Wolff,et al.  Expression of Thy-1 antigen by murine epidermal cells. , 1983, The Journal of investigative dermatology.

[200]  C. Janeway,et al.  Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells , 1983, The Journal of experimental medicine.

[201]  P. Capel,et al.  Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells , 1983, Nature.

[202]  E. Reinherz,et al.  Comparison of T3-associated 49- and 43-kilodalton cell surface molecules on individual human T-cell clones: evidence for peptide variability in T-cell receptor structures. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[203]  J. Borst,et al.  The T3 complex on human T lymphocytes involves four structurally distinct glycoproteins. , 1983, The Journal of biological chemistry.

[204]  S. Tonegawa.  Somatic generation of antibody diversity , 1983, Nature.

[205]  P. Marrack,et al.  The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody , 1983, The Journal of experimental medicine.

[206]  E. Reinherz,et al.  Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex , 1983, The Journal of experimental medicine.

[207]  P. Krammer,et al.  T cell hybrids , 1983 .

[208]  J. Allison,et al.  Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody. , 1982, Journal of immunology.

[209]  J. Borst,et al.  The role of T cell differentiation markers in antigen-specific and lectin-dependent cellular cytotoxicity mediated by T8+ and T4+ human cytotoxic T cell clones directed at class I and class II MHC antigens. , 1982, Journal of immunology.

[210]  R. Michell,et al.  Inositol lipid metabolism in dividing and differentiating cells. , 1982, Cell calcium.

[211]  F. Alt,et al.  Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[212]  J. Borst,et al.  Complexity of the human T lymphocyte-specific cell surface antigen T3. , 1982, Journal of immunology.

[213]  R. Tsien,et al.  T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes , 1982, Nature.

[214]  E. Jenkinson,et al.  Detection of Thy‐1, T‐200, Lyt‐1 and Lyt‐2‐bearing cells in the developing lymphoid organs of the mouse embryo in vivo and in vitro , 1982, European journal of immunology.

[215]  T. Chang,et al.  Regulation of influenza virus-specific cytotoxic T cell responses by monoclonal antibody to a human T cell differentiation antigen. , 1981, Journal of immunology.

[216]  R. Good,et al.  Inhibition of specific cell-mediated cytotoxicity by monoclonal antibodies to human T cell antigens. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[217]  C. Kaplan,et al.  Seeding of the 10-day mouse embryo thymic rudiment by lymphocyte precursors in vitro. , 1981, Journal of immunology.

[218]  T. Chang,et al.  Does OKT3 monoclonal antibody react with an antigen-recognition structure on human T cells? , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[219]  M. Lipinski,et al.  Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man , 1981, The Journal of experimental medicine.

[220]  U. Hämmerling,et al.  Lyt 1+23− cells appear in the thymus before Lyt 123+ cells , 1981, Nature.

[221]  F. Bach,et al.  T cell clones , 1981 .

[222]  Van Wauwe Jp,et al.  OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties. , 1980 .

[223]  E. Reinherz,et al.  Monoclonal antibodies defining distinctive human T cell surface antigens. , 1979, Science.

[224]  R M Zinkernagel,et al.  MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness. , 1979, Advances in immunology.

[225]  G. Shearer,et al.  Major histocompatibility complex restricted cell-mediated immunity. , 1977, Advances in immunology.

[226]  F. Burnet.  A modification of jerne's theory of antibody production using the concept of clonal selection , 1976, CA: a cancer journal for clinicians.

[227]  C. Milstein,et al.  Continuous cultures of fused cells secreting antibody of predefined specificity , 1975, Nature.

[228]  D. Shreffler,et al.  H-2 dependence of co-operation between T and B cells in vivo. , 1972, Journal of immunology.

[229]  M. Moore,et al.  EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS , 1967, The Journal of experimental medicine.

[230]  W. Dreyer,et al.  The molecular basis of antibody formation: a paradox. , 1965, Proceedings of the National Academy of Sciences of the United States of America.