Dose calculation formalisms and consensus dosimetry parameters for intravascular brachytherapy dosimetry: Recommendations of the AAPM Therapy Physics Committee Task Group No. 149.

Since the publication of AAPM Task Group 60 report in 1999, a considerable amount of dosimetry data for the three coronary brachytherapy systems in use in the United States has been reported. A subgroup, Task Group 149, of the AAPM working group on Special Brachytherapy Modalities (Bruce Thomadsen, Chair) was charged to develop recommendations for dose calculation formalisms and the related consensus dosimetry parameters. The recommendations of this group are presented here. For the Cordis Ir192 and Novoste Sr90∕Y90 systems, the original TG-43 formalism in spherical coordinates should be used along with the consensus values of the dose rate constant, geometry function, radial dose function, and anisotropy function for the single seeds. Contributions from the single seeds should be added linearly for the calculation of dose distributions from a source train. For the Guidant P32 wire system, the modified TG-43 formalism in cylindrical coordinates along with the recommended data for the 20 and 27mm wires should be used. Data tables for the 6, 10, 14, 18, and 22 seed trains of the Cordis system, 30, 40, and 60mm seed trains of the Novoste system, and the 20 and 27mm wires of the Guidant system are presented along with our rationale and methodology for selecting the consensus data. Briefly, all available datasets were compared with each other and the consensus dataset was either an average of available data or the one obtained from the most densely populated study; in most cases this was a Monte Carlo calculation.

[1]  D Baltas,et al.  Dosimetry comparison of 192Ir sources. , 2002, Medical physics.

[2]  G. D. Valdez,et al.  ITS: the integrated TIGER series of electron/photon transport codes-Version 3.0 , 1991, Conference Record of the 1991 IEEE Nuclear Science Symposium and Medical Imaging Conference.

[3]  Peter E Metcalfe,et al.  Radiochromic film for medical radiation dosimetry , 2003 .

[4]  S. Chiu‐Tsao,et al.  Thermoluminescent dosimetry of the Symmetra 125I model I25.S06 interstitial brachytherapy seed. , 2001, Medical physics.

[5]  K. Harte,et al.  A new miniature x-ray source for interstitial radiosurgery: device description. , 1996, Medical physics.

[6]  J. Williamson,et al.  Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations. , 2004 .

[7]  P. Teirstein,et al.  Intracoronary radiation therapy for multi‐drug resistant in‐stent restenosis: Initial clinical experience , 2007, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[8]  S. Chiu‐Tsao,et al.  The use of cylindrical coordinates for treatment planning parameters of an elongated 192Ir source. , 2001, International journal of radiation oncology, biology, physics.

[9]  R Wang,et al.  A Monte Carlo calculation of dosimetric parameters of 90Sr/90Y and 192Ir SS sources for intravascular brachytherapy. , 2000, Medical physics.

[10]  J. Fernández-Varea,et al.  Characterization of a high-dose-rate 90Sr-90Y source for intravascular brachytherapy by using the Monte Carlo code PENELOPE. , 2002, Physics in medicine and biology.

[11]  P. Serruys,et al.  A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. , 2002, The New England journal of medicine.

[12]  X. Li,et al.  Monte Carlo characterization of a 32P source for intravascular brachytherapy. , 2001, Medical physics.

[13]  Z. Chen,et al.  Dose rate constant and energy spectrum of interstitial brachytherapy sources. , 2001, Medical physics.

[14]  R. Sloboda,et al.  Influence of source geometry and materials on the transverse axis dosimetry of 192Ir brachytherapy sources. , 1998, Physics in medicine and biology.

[15]  A. Rankine,et al.  A handbook of radioactivity measurements procedures: NCRP Report No. 58, Second Edition (Bethesda, MD 20814, USA, 1985) pp. XVI + 592 , 1985 .

[16]  D Baltas,et al.  Beta versus gamma dosimetry close to Ir-192 brachytherapy sources. , 2001, Medical physics.

[17]  Dosimetry of 192Ir sources used for endovascular brachytherapy. , 2001, Physics in medicine and biology.

[18]  C. Soares,et al.  A high-precision, high-resolution and fast dosimetry system for beta sources applied in cardiovascular brachytherapy. , 2000, Medical physics.

[19]  R. Collé,et al.  Chemical digestion and radionuclidic assay of TiNi-encapsulated 32P intravascular brachytherapy sources. , 1999, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[20]  M. Stabin.  Dosimetry of External Beta Rays for Radiation Protection , 1998 .

[21]  J F Williamson,et al.  Comparison of measured and calculated dose rates in water near I-125 and Ir-192 seeds. , 1991, Medical physics.

[22]  S. Chiu‐Tsao,et al.  A new treatment planning formalism for catheter-based beta sources used in intravascular brachytherapy. , 2001, Cardiovascular radiation medicine.

[23]  A. Branzi,et al.  32P brachytherapy in the treatment of complex Cypher in-stent restenosis. , 2005, Journal of interventional cardiology.

[24]  D. Schaart.  The scaling method applied to beta particle line sources with a finite diameter. , 2002, Medical physics.

[25]  J. Sempau,et al.  PENELOPE-2006: A Code System for Monte Carlo Simulation of Electron and Photon Transport , 2009 .

[26]  S. Chiu‐Tsao,et al.  Verification of Ir-192 near source dosimetry using GAFCHROMIC film. , 2004, Medical physics.

[27]  Firas Mourtada,et al.  Dosimetry characterization of a 32P source wire used for intravascular brachytherapy with automated stepping. , 2003, Medical physics.

[28]  M. Rivard.  Refinements to the geometry factor used in the AAPM Task Group Report No. 43 necessary for brachytherapy dosimetry calculations. American Association of Physicists in Medicine. , 1999, Medical physics.

[29]  Dosimetric characteristics of the Novoste Beta-Cath 90Sr/Y source trains at submillimeter distances. , 2004, Medical physics.

[30]  S. Chiu‐Tsao,et al.  High beta and electron dose from 192Ir: implications for "gamma" intravascular brachytherapy. , 2002, International journal of radiation oncology, biology, physics.

[31]  R. Jeraj,et al.  Comparisons between MCNP, EGS4 and experiment for clinical electron beams. , 1999, Physics in medicine and biology.

[32]  J. Feldmeier,et al.  Dosimetric characteristics of a linear array of γ or β‐emitting seeds in intravascular irradiation: Monte Carlo studies for the AAPM TG‐43/60 formalism , 2003 .

[33]  J. F. Briesmeister.  MCNP-A General Monte Carlo N-Particle Transport Code , 1993 .

[34]  B. Clark,et al.  Experimental determination of dosimetry functions of Ir-192 sources. , 1998, Medical physics.

[35]  N. B. Gove,et al.  Log-f tables for beta decay , 1971 .

[36]  W. Cross.  Variation of beta dose attenuation in different media. , 1968, Physics in medicine and biology.

[37]  R Jeraj,et al.  Parameter dependence of the MCNP electron transport in determining dose distributions. , 2002, Medical physics.

[38]  S. Silber,et al.  Intracoronary beta-radiation to reduce restenosis after balloon angioplasty and stenting; the Beta Radiation In Europe (BRIE) study. , 2002, European heart journal.

[39]  P. Tripuraneni.  The future of CART in the era of drug eluting stents: "It's not over until it's over". Counterpoint. , 2003, Brachytherapy.

[40]  R Waksman,et al.  Endovascular beta-radiation to reduce restenosis after coronary balloon angioplasty: results of the beta energy restenosis trial (BERT). , 1998, Circulation.

[41]  R Nath,et al.  Intravascular brachytherapy physics: report of the AAPM Radiation Therapy Committee Task Group no. 60. American Association of Physicists in Medicine. , 1999, Medical physics.

[42]  T. Loftus,et al.  Standardization of Iridium-192 Gamma-Ray Sources in Terms of Exposure. , 1980, Journal of research of the National Bureau of Standards.

[43]  F. Mourtada,et al.  A segmented 32P source Monte Carlo model to derive AAPM TG-60 dosimetric parameters used for intravascular brachytherapy. , 2004, Medical physics.

[44]  J J Mazeron,et al.  Prescribing, recording, and reporting in endovascular brachytherapy. Quality assurance, equipment, personnel and education. , 2001, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[45]  J. Dempsey,et al.  Validation of a precision radiochromic film dosimetry system for quantitative two-dimensional imaging of acute exposure dose distributions. , 2000, Medical physics.

[46]  J. Williamson,et al.  Comment on “Let's abandon geometry factors other than that of a point source in brachytherapy dosimetry” [Med Phys. 29, 1917–1918 (2002)] , 2002 .

[47]  E. Kouwenhoven,et al.  Variation in interpretation of the AAPM TG-43 geometry factor leads to unclearness in brachytherapy dosimetry. , 2001, Medical physics.

[48]  Gregg W Stone,et al.  A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. , 2004, The New England journal of medicine.

[49]  R A Schatz,et al.  Catheter-based radiotherapy to inhibit restenosis after coronary stenting. , 1997, The New England journal of medicine.

[50]  P. Teirstein,et al.  Intracoronary Radiation Therapy Improves the Clinical and Angiographic Outcomes of Diffuse In-Stent Restenotic Lesions: Results of the Washington Radiation for In-Stent Restenosis Trial for Long Lesions (Long WRIST) Studies , 2003, Circulation.

[51]  C. Kirisits,et al.  Determination and application of the reference isodose length (RIL) for commercial endovascular brachytherapy devices. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[52]  D Flühs,et al.  Direct reading measurement of absorbed dose with plastic scintillators--the general concept and applications to ophthalmic plaque dosimetry. , 1996, Medical physics.

[53]  X. Li,et al.  IVBTMC, a Monte Carlo dose calculation tool for intravascular brachytherapy. , 2002, Medical physics.

[54]  Antonio M Lallena,et al.  Dosimetry characterization of 32P intravascular brachytherapy source wires using Monte Carlo codes PENELOPE and GEANT4. , 2004, Medical physics.

[55]  K. Kent,et al.  Intravascular brachytherapy versus drug-eluting stents for the treatment of patients with drug-eluting stent restenosis. , 2006, The American journal of cardiology.

[56]  Dennis R Schaart,et al.  A comparison of MCNP4C electron transport with ITS 3.0 and experiment at incident energies between 100 keV and 20 MeV: influence of voxel size, substeps and energy indexing algorithm. , 2002, Physics in medicine and biology.

[57]  P. Fitzgerald,et al.  Intracoronary gamma-radiation therapy after angioplasty inhibits recurrence in patients with in-stent restenosis. , 2000, Circulation.

[58]  P. Teirstein,et al.  Localized intracoronary gamma-radiation therapy to inhibit the recurrence of restenosis after stenting. , 2001, The New England journal of medicine.

[59]  J. Moses,et al.  Sirolimus-eluting stents vs. standard stents in patients with stenosis in a native coronary artery , 2004 .

[60]  Icru.  Prescribing, recording, and reporting photon beam therapy , 1993 .

[61]  X. Li,et al.  Dosimetric comparison of two 90Sr/90Y sources for intravascular brachytherapy: an EGSnrc Monte Carlo calculation. , 2002, Physics in medicine and biology.

[62]  Richard R. Heuser,et al.  Randomized Trial of 90Sr/90Y β-Radiation Versus Placebo Control for Treatment of In-Stent Restenosis , 2002 .

[63]  M. Leon,et al.  Intracoronary β-Radiation Therapy Inhibits Recurrence of In-Stent Restenosis , 2000 .

[64]  S. Chiu‐Tsao,et al.  Treatment planning dosimetric parameters for 192Ir seed at short distances: effects of air channels and neighboring seeds based on Monte Carlo study. , 2004, Medical physics.

[65]  J F Williamson,et al.  Clinical implementation of AAPM Task Group 32 recommendations on brachytherapy source strength specification. , 1991, Medical physics.

[66]  X. Li,et al.  Dosimetric perturbations of linear array of beta-emitter seeds and metallic stent in intravascular brachytherapy. , 2000, Medical physics.

[67]  C G Soares,et al.  Calibration and characterization of beta-particle sources for intravascular brachytherapy. , 1998, Medical physics.

[68]  Experimental dosimetry of a 32P catheter-based endovascular brachytherapy source. , 2003, Physics in medicine and biology.

[69]  Radiochromic film dosimetry of a high dose rate beta source for intravascular brachytherapy. , 1999, Medical physics.

[70]  R Wang,et al.  Monte Carlo dose calculations of beta-emitting sources for intravascular brachytherapy: a comparison between EGS4, EGSnrc, and MCNP. , 2001, Medical physics.

[71]  Jeffrey W Moses,et al.  Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. , 2003, The New England journal of medicine.

[72]  J. Meli.  Let's abandon geometry factors other than that of a point source in brachytherapy dosimetry. , 2002, Medical physics.

[73]  D. Schaart,et al.  The radial depth-dose distribution of a 188W/188Re beta line source measured with novel, ultra-thin TLDs in a PMMA phantom: comparison with Monte Carlo simulations. , 2002, Physics in medicine and biology.

[74]  S. Seltzer,et al.  Dosimetry characterization of 32P catheter-based vascular brachytherapy source wire. , 2000, Medical physics.

[75]  A. Lansky,et al.  Five-year clinical and angiographic follow-up after intracoronary iridium-192 radiation therapy. , 2002, Cardiovascular radiation medicine.

[76]  A. Yeung,et al.  Use of localised intracoronary β radiation in treatment of in-stent restenosis: the INHIBIT randomised controlled trial , 2002, The Lancet.

[77]  J. Galvin,et al.  Radiochromic film dosimetry: recommendations of AAPM Radiation Therapy Committee Task Group 55. American Association of Physicists in Medicine. , 1998, Medical physics.

[78]  L. Anderson,et al.  Dosimetry of interstitial brachytherapy sources: Recommendations of the AAPM Radiation Therapy Committee Task Group No. 43 , 1995 .

[79]  D. Schaart,et al.  On the applicability of the AAPM TG-60/TG-43 dose calculation formalism to intravascular line sources: proposal for an adapted formalism. , 2001, Medical physics.

[80]  L. Sakelliou,et al.  Limitations of the point and line source approximations for the determination of geometry factors around brachytherapy sources. , 2000, Medical physics.

[81]  Dosimetry of source stepping for intravascular brachytherapy. , 2001, Cardiovascular radiation medicine.

[82]  A. Yeung,et al.  Inhibition of Restenosis With &bgr;-Emitting Radiotherapy: Report of the Proliferation Reduction With Vascular Energy Trial (PREVENT) , 2000, Circulation.

[83]  C. Soares.  Radiochromic film dosimetry , 2006 .

[84]  R. Capote,et al.  Anisotropy function for 192Ir low-dose-rate brachytherapy sources: an EGS4 Monte Carlo study. , 2001, Physics in medicine and biology.

[85]  Dose rate table for a 32P intravascular brachytherapy source from Monte Carlo calculations. , 2001, Medical physics.