Significance of Pulmonary Elastic and Viscous Resistance in Orthopnea

The mechanical properties of the lungs were measured in the sitting and supine positions in 5 normal subjects and in 5 patients with orthopnea due to congestive heart failure. The patients had higher elastic and viscous resistances in the sitting position. Recumbency increased both resistances in both groups but there was a disproportionate increase in the viscous resistance of the patients. This increase was most marked in late expiration and early inspiration. The significance of these findings to orthopnea is discussed.

[1]  H. D. Green,et al.  Adrenergic Drugs and Blockade on Coronary Arterioles and Myocardial Contraction , 1956, Circulation research.

[2]  R. Cherniack.  The physical properties of the lung in chronic obstructive pulmonary emphysema. , 1956, The Journal of clinical investigation.

[3]  J. Mead,et al.  The mechanical properties of the lungs in emphysema. , 1955, The Journal of clinical investigation.

[4]  D. L. Fry,et al.  The mechanics of pulmonary ventilation in patients with heart diseases. , 1954, The American journal of medicine.

[5]  M. Mcilroy,et al.  The work of breathing in normal subjects. , 1954, Clinical science.

[6]  M. Mcilroy,et al.  The work of breathing in mitral stenosis. , 1954, Clinical science.

[7]  R V CHRISTIE,et al.  Dyspnœa in Relation to the Visco-Elastic Properties of the Lung , 1953, Proceedings of the Royal Society of Medicine.

[8]  G. Lee,et al.  The intrathoracic blood volume in mitral stenosis and left ventricular failure. , 1951, Clinical science.

[9]  H. S. Wells,et al.  STUDIES OF THE PULMONARY CIRCULATION. II. THE CIRCULATION TIME FROM THE PULMONARY ARTERY TO THE FEMORAL ARTERY AND THE QUANTITY OF BLOOD IN THE LUNGS IN PATIENTS WITH MITRAL STENOSIS AND IN PATIENTS WITH LEFT VENTRICULAR FAILURE. , 1949, The Journal of clinical investigation.

[10]  D. Richards,et al.  Pulmonary in-sufficiency I. Physiological classification, clinical methods of analysis, standard values in normal subjects , 1948 .

[11]  W. B. Kountz,et al.  INTRAPLEURAL PRESSURE IN HEALTH AND DISEASE AND ITS INFLUENCE ON BODY FUNCTION , 1935 .

[12]  R. Christie,et al.  THE INTRAPLEURAL PRESSURE IN CONGESTIVE HEART FAILURE AND ITS CLINICAL SIGNIFICANCE. , 1934, The Journal of clinical investigation.

[13]  W. Hamilton,et al.  MECHANISM OF THE POSTURAL REDUCTION IN VITAL CAPACITY IN RELATION TO ORTHOPNEA AND STORAGE OF BLOOD IN THE LUNGS , 1932 .

[14]  F. Peabody.  CLINICAL STUDIES ON THE RESPIRATION: III. A MECHANICAL FACTOR IN THE PRODUCTION OF DYSPNEA IN PATIENTS WITH CARDIAC DISEASE , 1917 .