IMMUNOGENETIC STUDIES ON METH‐A‐VACCINIA TUMOUR CELLS IN VIVO AND IN VITRO *

The expression of H‐2 antigenic specificities on Meth‐A and meth‐A‐vaccinia were compared. Their ability to inhibit complement dependent cytotoxicity of 51Cr‐labelled normal lymphoid target cells was tested by anti H‐2 sera of restricted specificity. Normal lymphocytes positive or negative for a particular specificity, were used as controls. With this assay the expression of H‐2‐like specificities of foreign haplotypes on Meth‐A cells passaged together with vaccinia virus was confirmed.

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