CD5 (OKT1) Augments CD3-Mediated Intracellular Signaling Events in Human T Lymphocytes

[1]  Y. Yashiro‐Ohtani,et al.  CD5 Costimulation Up-Regulates the Signaling to Extracellular Signal-Regulated Kinase Activation in CD4+CD8+ Thymocytes and Supports Their Differentiation to the CD4 Lineage1 , 2000, The Journal of Immunology.

[2]  Fernando A. Arosa,et al.  CD2 and CD3 associate independently with CD5 and differentially regulate signaling through CD5 in Jurkat T cells. , 1999, Journal of immunology.

[3]  A. Tarakhovsky,et al.  An influence of CD5 on the selection of CD4‐lineage T cells , 1999, European journal of immunology.

[4]  J. Sprent,et al.  Several Different Cell Surface Molecules Control Negative Selection of Medullary Thymocytes , 1999, The Journal of experimental medicine.

[5]  D. Andreu,et al.  Human CD5 signaling and constitutive phosphorylation of C-terminal serine residues by casein kinase II. , 1998, Journal of immunology.

[6]  A. Aruffo,et al.  A role for CD5 in cognate interactions between T cells and B cells, and identification of a novel ligand for CD5. , 1998, International immunology.

[7]  V. Lang,et al.  In vivo association of CD5 with tyrosine-phosphorylated ZAP-70 and p21 phospho-zeta molecules in human CD3+ thymocytes. , 1997, Journal of immunology.

[8]  M. Simarro,et al.  The cytoplasmic domain of CD5 mediates both TCR/CD3-dependent and -independent diacylglycerol production. , 1997, Journal of immunology.

[9]  R. Mage,et al.  CD5 is a potential selecting ligand for B cell surface immunoglobulin framework region sequences , 1996, The Journal of experimental medicine.

[10]  S. Berney,et al.  Phosphatidylinositol hydrolysis in freshly isolated human T lymphocytes. , 1995, Journal of immunological methods.

[11]  K. Rajewsky,et al.  A role for CD5 in TCR-mediated signal transduction and thymocyte selection. , 1995, Science.

[12]  S. Muthukkumar,et al.  Involvement of CD5 in Th1 and Th2 contact-mediated rescue of anti-mu and ionomycin induced growth inhibition in a B cell lymphoma. , 1995, International Immunology.

[13]  R. Testi,et al.  The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells. , 1994, Immunology today.

[14]  J. Ceuppens,et al.  Ligation of the CD5 or CD28 molecules on resting human T cells induces expression of the early activation antigen CD69 by a calcium- and tyrosine kinase-dependent mechanism. , 1993, Immunology.

[15]  C. Rudd,et al.  CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor zeta chain/CD3 and protein-tyrosine kinases p56lck and p59fyn. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[16]  M. Kaliner,et al.  Phospholipase C-gamma 1 is translocated to the membrane of rat basophilic leukemia cells in response to aggregation of IgE receptors. , 1992, Journal of immunology.

[17]  D. Cantrell,et al.  Intracellular events involved in CD5-induced human T cell activation and proliferation. , 1992, Journal of immunology.

[18]  H. Velde,et al.  The B-cell surface protein CD72/Lyb-2 is the ligand for CDS , 1991, Nature.

[19]  K. Horgan,et al.  Costimulation of proliferative responses of resting CD4+ T cells by the interaction of VLA-4 and VLA-5 with fibronectin or VLA-6 with laminin. , 1990, Journal of immunology.

[20]  C. June,et al.  Stimulation of CD5 enhances signal transduction by the T cell antigen receptor. , 1990, The Journal of clinical investigation.

[21]  J. Imboden,et al.  The T-cell antigen receptor regulates sustained increases in cytoplasmic free Ca2+ through extracellular Ca2+ influx and ongoing intracellular Ca2+ mobilization. , 1987, The Biochemical journal.

[22]  Arthur Weiss,et al.  The role of protein kinase C in transmembrane signaling by the T cell antigen receptor complex. Effects of stimulation with soluble or immobilized CD3 antibodies. , 1987, Journal of immunology.

[23]  P. Rabinovitch,et al.  CD5 antibodies increase intracellular ionized calcium concentration in T cells. , 1987, Journal of immunology.

[24]  P. Majerus,et al.  The metabolism of phosphoinositide-derived messenger molecules. , 1986, Science.

[25]  W. Farrar,et al.  Association of protein kinase C activation with IL 2 receptor expression. , 1986, Journal of Immunology.

[26]  E. Neufeld,et al.  Production of phosphoinositide-derived messengers , 1984, Cell.

[27]  T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. , 1983, Journal of immunological methods.

[28]  J. Hawthorne,et al.  Phosphatidylinositol kinase and diphosphoinositide kinase of rat kidney cortex: properties and subcellular localization. , 1976, The Biochemical journal.