Discovery of the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABA(A) alpha5 inverse agonist series.
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F. Blasco | F. Knoflach | G. Trube | Maria-Clemencia Hernández | H. Fischer | T. Ballard | R. Porter | A. Thomas | B. Büttelmann | H. Stadler | J. Wichmann | H. Knust | James R. Martin | Guido Achermann | Pierre-Emmanuel Broutin | M. Graf | Peter Hilty | Andreas Koblet | A. Kurt | R. Masciadri | Maria-Clemencia Hernandez