Pten Regulates Neuronal Arborization and Social Interaction in Mice

[1]  S. Baker,et al.  Neuron‐specific enolase‐cre mouse line with cre activity in specific neuronal populations , 2006, Genesis.

[2]  C. Hoogenraad,et al.  Control of Dendritic Arborization by the Phosphoinositide-3′-Kinase–Akt–Mammalian Target of Rapamycin Pathway , 2005, The Journal of Neuroscience.

[3]  U. Frith,et al.  Vagaries of Visual Perception in Autism , 2005, Neuron.

[4]  N. Hay,et al.  The Akt-mTOR tango and its relevance to cancer. , 2005, Cancer cell.

[5]  S. Baron-Cohen,et al.  Autism: a window onto the development of the social and the analytic brain. , 2005, Annual review of neuroscience.

[6]  P. Bolton,et al.  Consensus clinical guidelines for the assessment of cognitive and behavioural problems in Tuberous Sclerosis , 2005, European Child & Adolescent Psychiatry.

[7]  W. Greenough,et al.  From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome , 2005, Nature Reviews Neuroscience.

[8]  B. Luikart,et al.  TrkB Has a Cell-Autonomous Role in the Establishment of Hippocampal Schaffer Collateral Synapses , 2005, The Journal of Neuroscience.

[9]  C Eng,et al.  Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations , 2005, Journal of Medical Genetics.

[10]  Karl Herrup,et al.  A question of balance: a proposal for new mouse models of autism , 2005, International Journal of Developmental Neuroscience.

[11]  T. Kemper,et al.  Neuroanatomic observations of the brain in autism: a review and future directions , 2005, International Journal of Developmental Neuroscience.

[12]  C. Ribak,et al.  Integration of newly born dentate granule cells into adult brains: hypotheses based on normal and epileptic rodents , 2005, Brain Research Reviews.

[13]  H. Zoghbi,et al.  Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome. , 2005, Human molecular genetics.

[14]  K. Kaibuchi,et al.  GSK-3β Regulates Phosphorylation of CRMP-2 and Neuronal Polarity , 2005, Cell.

[15]  Y. Rao,et al.  Both the Establishment and the Maintenance of Neuronal Polarity Require Active Mechanisms Critical Roles of GSK-3β and Its Upstream Regulators , 2005, Cell.

[16]  M. Stoltenberg,et al.  Immersion Autometallography: Histochemical In Situ Capturing of Zinc Ions in Catalytic Zinc-Sulfur Nanocrystals , 2004, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[17]  Nobumasa Kato,et al.  Association between the neurofibromatosis‐1 (NF1) locus and autism in the Japanese population , 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[18]  D. Gutmann,et al.  Pten Loss Causes Hypertrophy and Increased Proliferation of Astrocytes In vivo , 2004, Cancer Research.

[19]  J. Crawley.  Designing mouse behavioral tasks relevant to autistic-like behaviors. , 2004, Mental retardation and developmental disabilities research reviews.

[20]  J. Piven,et al.  Sociability and preference for social novelty in five inbred strains: an approach to assess autistic‐like behavior in mice , 2004, Genes, brain, and behavior.

[21]  Shunyou Wang,et al.  PTENless means more. , 2004, Developmental biology.

[22]  M. Radrizzani,et al.  Correlation between synaptogenesis and the PTEN phosphatase expression in dendrites during postnatal brain development. , 2004, Brain research. Molecular brain research.

[23]  R. McLendon,et al.  Mutations of PIK3CA in Anaplastic Oligodendrogliomas, High-Grade Astrocytomas, and Medulloblastomas , 2004, Cancer Research.

[24]  D. Amaral,et al.  The Amygdala Is Enlarged in Children But Not Adolescents with Autism; the Hippocampus Is Enlarged at All Ages , 2004, The Journal of Neuroscience.

[25]  T. Südhof,et al.  The Presynaptic Active Zone Protein RIM1α Is Critical for Normal Learning and Memory , 2004, Neuron.

[26]  M. Karayiorgou,et al.  Convergent evidence for impaired AKT1-GSK3β signaling in schizophrenia , 2004, Nature Genetics.

[27]  H. Zoghbi.  Postnatal Neurodevelopmental Disorders: Meeting at the Synapse? , 2003, Science.

[28]  S. Baker,et al.  mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[29]  L. Cantley,et al.  Targeting the PI3K-Akt pathway in human cancer: rationale and promise. , 2003, Cancer cell.

[30]  L. Cantley,et al.  United at last: the tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target of rapamycin (mTOR) signalling. , 2003, Biochemical Society transactions.

[31]  B. Oostra,et al.  The Fragile X Syndrome Protein FMRP Associates with BC1 RNA and Regulates the Translation of Specific mRNAs at Synapses , 2003, Cell.

[32]  C. Kahn,et al.  Regulation of Myocardial Contractility and Cell Size by Distinct PI3K-PTEN Signaling Pathways , 2002, Cell.

[33]  L. Hennighausen,et al.  Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland. , 2002, Development.

[34]  A. Markus,et al.  Raf and Akt Mediate Distinct Aspects of Sensory Axon Growth , 2002, Neuron.

[35]  J. Piven,et al.  Structural and functional magnetic resonance imaging of autism , 2002, International Journal of Developmental Neuroscience.

[36]  C. Eng,et al.  Protean PTEN: form and function. , 2002, American journal of human genetics.

[37]  C. Andres.  Molecular genetics and animal models in autistic disorder , 2002, Brain Research Bulletin.

[38]  A. Gingras,et al.  A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[39]  P. Burger,et al.  Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease , 2001, Nature Genetics.

[40]  T. Mak,et al.  Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease , 2001, Nature Genetics.

[41]  A. Trumpp,et al.  Negative Regulation of Neural Stem/Progenitor Cell Proliferation by the Pten Tumor Suppressor Gene in Vivo , 2001, Science.

[42]  R. Rothermel,et al.  Autism in tuberous sclerosis complex is related to both cortical and subcortical dysfunction , 2001, Neurology.

[43]  P. Gean,et al.  A Role for the PI-3 Kinase Signaling Pathway in Fear Conditioning and Synaptic Plasticity in the Amygdala , 2001, Neuron.

[44]  L. Hoefsloot,et al.  PTEN mutation in a family with Cowden syndrome and autism. , 2001, American journal of medical genetics.

[45]  M. Lauritsen,et al.  The genetics of autism , 2001, Acta psychiatrica Scandinavica.

[46]  T. Sasaki,et al.  T cell-specific loss of Pten leads to defects in central and peripheral tolerance. , 2001, Immunity.

[47]  M. Geyer,et al.  Effects of strain and serotonergic agents on prepulse inhibition and habituation in mice , 2000, Neuropharmacology.

[48]  C. Barthélémy,et al.  Association study of the NF1 gene and autistic disorder. , 1999, American journal of medical genetics.

[49]  L. Schriml,et al.  Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity. , 1999, Journal of the National Cancer Institute.

[50]  Jon T. Willie,et al.  Narcolepsy in orexin Knockout Mice Molecular Genetics of Sleep Regulation , 1999, Cell.

[51]  E. Fombonne,et al.  Microcephaly and Macrocephaly in Autism , 1999, Journal of autism and developmental disorders.

[52]  L. Klesse,et al.  p21 Ras and Phosphatidylinositol-3 Kinase Are Required for Survival of Wild-Type and NF1 Mutant Sensory Neurons , 1998, The Journal of Neuroscience.

[53]  C. Eng,et al.  Germline PTEN mutation in a family with Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome. , 1998, American journal of medical genetics.

[54]  Tomohiko Maehama,et al.  The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate* , 1998, The Journal of Biological Chemistry.

[55]  R. Crowder,et al.  Phosphatidylinositol 3-Kinase and Akt Protein Kinase Are Necessary and Sufficient for the Survival of Nerve Growth Factor-Dependent Sympathetic Neurons , 1998, The Journal of Neuroscience.

[56]  Richard Paylor,et al.  Social Interaction and Sensorimotor Gating Abnormalities in Mice Lacking Dvl1 , 1997, Cell.

[57]  P. Cohen,et al.  Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B , 1995, Nature.

[58]  G. Dawson,et al.  Use of the elevated plus maze in the search for novel anxiolytic agents. , 1995, Trends in pharmacological sciences.

[59]  B. Leventhal,et al.  Autism and tuberous sclerosis , 1991, Journal of autism and developmental disorders.

[60]  D. Amaral.  A golgi study of cell types in the hilar region of the hippocampus in the rat , 1978, The Journal of comparative neurology.

[61]  吉村 武.  GSK-3β regulates phosphorylation of CRMP-2 and neuronal polarity , 2005 .

[62]  Philippe Soriano.  Generalized lacZ expression with the ROSA26 Cre reporter strain , 1999, Nature Genetics.

[63]  T. Freund,et al.  Distribution, ultrastructure, and connectivity of calretinin‐immunoreactive mossy cells of the mouse dentate gyrus , 1997, Hippocampus.