Onset of adult varicella in relation to rural or urban origin and its complications.

OBJECTIVES To determine area of origin of adult varicella patients, whether rural or urban, to compare the mean interval between leaving the area of origin and onset of varicella in adults of rural origin in comparison with those of urban origin and to observe its complications. STUDY DESIGN A cross-sectional study. PLACE AND DURATION OF STUDY Combined Military Hospital, Abbottabad, from January to December 2006. PATIENTS AND METHODS All patients over the age of 18 years, presenting with acute illness clinically, suggestive of varicella were included in the study. A specially designed proforma was filled for each patient separately, which included demographic features as well as area of origin, whether rural or urban, and the age at which they left the area of origin. These patients were examined, treated and assessed clinically on regular basis for the progress of the disease as well as for its possible local or systemic complications. Data analysis was done by using statistical programme SPSS-10. RESULTS Out of 9155 adult patients, 156 (1.70%) had varicella, including 128 (82.1%) males and 28 (17.9%) females. Origin was rural in 125 (80.1%) and urban in 31 (19.9%) patients. Mean interval between leaving area of origin and developing varicella in those of rural origin was 01.79+/-01.78 years and that in patients of urban origin was 03.37+/-05.72 years (p+/-0.009). None of the patients developed any complication of the disease. CONCLUSION Varicella in adults is generally a benign illness. It is more common among adult males of rural origin and the interval between leaving the area of origin and onset of varicella in these patients is significantly less as compared to that in adults of urban origin.

[1]  黄亚明 eMedicine , 2009 .

[2]  C. Dorobăț,et al.  [Varicella-zoster infection--extreme clinical aspects]. , 2006, Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi.

[3]  G. Goldman The Case against Universal Varicella Vaccination , 2006, International journal of toxicology.

[4]  D. Bernstein,et al.  Variability and gender differences in memory T cell immunity to varicella-zoster virus in healthy adults. , 2006, Vaccine.

[5]  Nadir Ali,et al.  Chicken pox associated thrombocytopenia in adults. , 2006, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.

[6]  Z. Memish,et al.  Chickenpox complications in Saudi Arabia: Is it time for routine varicella vaccination? , 2006, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

[7]  E. Castagnola,et al.  Varicella and its complications as cause of hospitalization. , 2005, Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive.

[8]  I. Pneumatikos,et al.  Varicella-zoster virus pneumonia in adults: report of 14 cases and review of the literature. , 2004, European journal of internal medicine.

[9]  A. Goldstein,et al.  Delayed disseminated Staphylococcus aureus infection following chickenpox , 2004, Journal of paediatrics and child health.

[10]  P. Böelle,et al.  Varicella in non-immune persons: incidence, hospitalization and mortality rates , 2002, Epidemiology and Infection.

[11]  Y. Hutagalung,et al.  Effect of climatic factors and population density on varicella zoster virus epidemiology within a tropical country. , 2001, The American journal of tropical medicine and hygiene.

[12]  B. Olowokure,et al.  Seroepidemiology of varicella-zoster in Pakistan. , 2000, The Southeast Asian journal of tropical medicine and public health.

[13]  K. O'Grady,et al.  High seroprevalence of antibodies to varicella zoster virus in adult women in a tropical climate , 2000, Tropical medicine & international health : TM & IH.

[14]  M. Lokeshwar,et al.  Age related seroprevalence of antibodies to varicella in India. , 2000, Indian pediatrics.

[15]  B. Mandal,et al.  Adult susceptibility to varicella in the tropics is a rural phenomenon due to the lack of previous exposure. , 1998, The Journal of infectious diseases.

[16]  Lee Review of varicella zoster seroepidemiology in India and South‐east Asia , 1998, Tropical medicine & international health : TM & IH.

[17]  Lee Bw Review of varicella zoster seroepidemiology in India and South‐east Asia , 1998 .

[18]  R Platt,et al.  The epidemiology of varicella and its complications. , 1995, The Journal of infectious diseases.

[19]  I. Pachón del Amo,et al.  [Update on chickenpox]. , 2006, Revista clinica espanola.

[20]  Isabel Peña-Rey,et al.  Actualización en varicela , 2006 .