Towards a federated neuroscientific knowledge management system using brain atlases

Abstract The topic of federated databases has received much attention within the domain of neuroinformatics and is widely perceived as the eventual solution to the problems inherent in building truly interoperable informatics systems. We describe a feasibility study of a methodology strategy for building federated informatics systems with a specific example from informatics approaches involving the neuroscientific literature. We examine the logistical issues concerning linking two database systems (CoCoMac and NeuroScholar) via a method based on the use of transformations between neuroanatomical parcellations (Stephan et al., Phil. Trans. R. Soc. London B 335 (2000) 37–54).

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