AMPA-ergic regulation of amyloid-β levels in an Alzheimer’s disease mouse model

[1]  Y. Sheline,et al.  Redundant Gs-coupled serotonin receptors regulate amyloid-β metabolism in vivo , 2016, Molecular Neurodegeneration.

[2]  F. C. Bennett,et al.  New tools for studying microglia in the mouse and human CNS , 2016, Proceedings of the National Academy of Sciences.

[3]  D. Gruol,et al.  IL-6 regulation of synaptic function in the CNS , 2015, Neuropharmacology.

[4]  Thomas Wisniewski,et al.  Clearance systems in the brain—implications for Alzheimer disease , 2015, Nature Reviews Neurology.

[5]  D. Holtzman,et al.  Three dimensions of the amyloid hypothesis: time, space and 'wingmen' , 2015, Nature Neuroscience.

[6]  L. Tan,et al.  Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease. , 2015, Annals of translational medicine.

[7]  S. Sensi,et al.  Age-Dependent Modifications of AMPA Receptor Subunit Expression Levels and Related Cognitive Effects in 3xTg-AD Mice , 2014, Front. Aging Neurosci..

[8]  S. Cregan,et al.  Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease , 2014, Molecular Brain.

[9]  Robert J. Williams,et al.  AMPA Receptor Activation Promotes Non-Amyloidogenic Amyloid Precursor Protein Processing and Suppresses Neuronal Amyloid-β Production , 2013, PloS one.

[10]  A. Quintana,et al.  Interleukin-6, a Major Cytokine in the Central Nervous System , 2012, International journal of biological sciences.

[11]  David G. Jones,et al.  Cortical development of AMPA receptor trafficking proteins , 2012, Front. Mol. Neurosci..

[12]  A. Fisher Cholinergic modulation of amyloid precursor protein processing with emphasis on M1 muscarinic receptor: perspectives and challenges in treatment of Alzheimer’s disease , 2012, Journal of neurochemistry.

[13]  M. Mintun,et al.  Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans , 2011, Proceedings of the National Academy of Sciences.

[14]  D. Holtzman,et al.  Opposing Synaptic Regulation of Amyloid-β Metabolism by NMDA Receptors In Vivo , 2011, The Journal of Neuroscience.

[15]  Denise C. Park,et al.  Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[16]  J. Morris,et al.  Alzheimer’s Disease: The Challenge of the Second Century , 2011, Science Translational Medicine.

[17]  Y. Sara,et al.  Use-Dependent AMPA Receptor Block Reveals Segregation of Spontaneous and Evoked Glutamatergic Neurotransmission , 2011, The Journal of Neuroscience.

[18]  Jee Hoon Roh,et al.  Neuronal activity regulates the regional vulnerability to amyloid-β deposition , 2011, Nature Neuroscience.

[19]  J. Morris,et al.  Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease , 2010, Science.

[20]  E. Capetillo-Zarate,et al.  Effects of Synaptic Modulation on β-Amyloid, Synaptophysin, and Memory Performance in Alzheimer's Disease Transgenic Mice , 2010, The Journal of Neuroscience.

[21]  Wenjun Gao,et al.  Development of calcium‐permeable AMPA receptors and their correlation with NMDA receptors in fast‐spiking interneurons of rat prefrontal cortex , 2010, The Journal of physiology.

[22]  J. Wess,et al.  Deletion of M1 Muscarinic Acetylcholine Receptors Increases Amyloid Pathology In Vitro and In Vivo , 2010, The Journal of Neuroscience.

[23]  P. S. St George-Hyslop,et al.  Group II Metabotropic Glutamate Receptor Stimulation Triggers Production and Release of Alzheimer's Amyloid β42 from Isolated Intact Nerve Terminals , 2010, The Journal of Neuroscience.

[24]  D. Dickson,et al.  Massive gliosis induced by interleukin‐6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[25]  Roberto Malinow,et al.  Amyloid beta from axons and dendrites reduces local spine number and plasticity , 2010, Nature Neuroscience.

[26]  Xiaowei Wang,et al.  PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification , 2009, Nucleic Acids Res..

[27]  Yan Wang,et al.  Characterizing the Appearance and Growth of Amyloid Plaques in APP/PS1 Mice , 2009, The Journal of Neuroscience.

[28]  Robert J. Williams,et al.  Synaptic NMDA Receptor Activation Stimulates α-Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-β Production , 2009, The Journal of Neuroscience.

[29]  E. Schuman,et al.  Partitioning the Synaptic Landscape: Distinct Microdomains for Spontaneous and Spike-Triggered Neurotransmission , 2009, Science Signaling.

[30]  Keith A. Johnson,et al.  Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease , 2009, The Journal of Neuroscience.

[31]  Athanasia Spandidos,et al.  A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance , 2008, BMC Genomics.

[32]  A. Deutch,et al.  Novel Selective Allosteric Activator of the M1 Muscarinic Acetylcholine Receptor Regulates Amyloid Processing and Produces Antipsychotic-Like Activity in Rats , 2008, The Journal of Neuroscience.

[33]  K. Moulder,et al.  Spontaneous and Evoked Glutamate Release Activates Two Populations of NMDA Receptors with Limited Overlap , 2008, The Journal of Neuroscience.

[34]  E. Marcello,et al.  Amyloid flirting with synaptic failure: towards a comprehensive view of Alzheimer's disease pathogenesis. , 2008, European journal of pharmacology.

[35]  Guojun Bu,et al.  Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo , 2008, Neuron.

[36]  R. Kauppinen,et al.  Proliferating Resident Microglia after Focal Cerebral Ischaemia in Mice , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[37]  H. Kettenmann,et al.  Microglia: active sensor and versatile effector cells in the normal and pathologic brain , 2007, Nature Neuroscience.

[38]  R. Huganir,et al.  The cell biology of synaptic plasticity: AMPA receptor trafficking. , 2007, Annual review of cell and developmental biology.

[39]  E. Schuman,et al.  Postsynaptic Decoding of Neural Activity: eEF2 as a Biochemical Sensor Coupling Miniature Synaptic Transmission to Local Protein Synthesis , 2007, Neuron.

[40]  Steven Finkbeiner,et al.  NMDA and AMPA receptors: old channels, new tricks , 2007, Trends in Neurosciences.

[41]  W. Klein,et al.  Aβ Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease , 2007, The Journal of Neuroscience.

[42]  R. Malinow,et al.  AMPAR Removal Underlies Aβ-Induced Synaptic Depression and Dendritic Spine Loss , 2006, Neuron.

[43]  E. Schuman,et al.  Miniature Neurotransmission Stabilizes Synaptic Function via Tonic Suppression of Local Dendritic Protein Synthesis , 2006, Cell.

[44]  G. Collingridge,et al.  Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation , 2006, Nature Neuroscience.

[45]  C. Duarte,et al.  Excitotoxicity mediated by Ca2+-permeable GluR4-containing AMPA receptors involves the AP-1 transcription factor , 2006, Cell Death and Differentiation.

[46]  L. Feig,et al.  Age-dependent Participation of Ras-GRF Proteins in Coupling Calcium-permeable AMPA Glutamate Receptors to Ras/Erk Signaling in Cortical Neurons* , 2006, Journal of Biological Chemistry.

[47]  Eric H. Chang,et al.  AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[48]  Steven Mennerick,et al.  Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo , 2005, Neuron.

[49]  E. Mackenzie,et al.  NMDA Receptor Activation Inhibits α-Secretase and Promotes Neuronal Amyloid-β Production , 2005, The Journal of Neuroscience.

[50]  Benjamin J. Shannon,et al.  Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory , 2005, The Journal of Neuroscience.

[51]  P. Seeburg,et al.  The AMPA Receptor Subunits GluR-A and GluR-B Reciprocally Modulate Spinal Synaptic Plasticity and Inflammatory Pain , 2004, Neuron.

[52]  R. Tanzi,et al.  Clearance of Alzheimer's Aβ Peptide The Many Roads to Perdition , 2004, Neuron.

[53]  D. Borchelt,et al.  APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1 , 2004, Neurobiology of Aging.

[54]  Nicholas R Wall,et al.  Regulation of Dendritic Protein Synthesis by Miniature Synaptic Events , 2004, Science.

[55]  B. Seed,et al.  A PCR primer bank for quantitative gene expression analysis. , 2003, Nucleic acids research.

[56]  D. Holtzman,et al.  In Vivo Assessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life , 2003, The Journal of Neuroscience.

[57]  P. Francis Glutamatergic systems in Alzheimer's disease , 2003, International journal of geriatric psychiatry.

[58]  M. Staufenbiel,et al.  Extracellular amyloid formation and associated pathology in neural grafts , 2003, Nature Neuroscience.

[59]  R. Malinow,et al.  APP Processing and Synaptic Function , 2003, Neuron.

[60]  M. Schwaninger,et al.  Interleukin-6 (IL-6): A Possible Neuromodulator Induced by Neuronal Activity , 2002, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[61]  D. Borchelt,et al.  Co-expression of multiple transgenes in mouse CNS: a comparison of strategies. , 2001, Biomolecular engineering.

[62]  Kortaro Tanaka,et al.  Enhanced Expression of Iba1, Ionized Calcium-Binding Adapter Molecule 1, After Transient Focal Cerebral Ischemia In Rat Brain , 2001, Stroke.

[63]  M. Schwaninger,et al.  Induction of Interleukin-6 by Depolarization of Neurons , 2000, The Journal of Neuroscience.

[64]  Robert J. Williams,et al.  Ca2+-Permeable AMPA Receptors Induce Phosphorylation of cAMP Response Element-Binding Protein through a Phosphatidylinositol 3-Kinase-Dependent Stimulation of the Mitogen-Activated Protein Kinase Signaling Cascade in Neurons , 1999, The Journal of Neuroscience.

[65]  Clive N Svendsen,et al.  Leukocyte Infiltration, Neuronal Degeneration, and Neurite Outgrowth after Ablation of Scar-Forming, Reactive Astrocytes in Adult Transgenic Mice , 1999, Neuron.

[66]  Yizheng Wang,et al.  AMPA receptor-mediated regulation of a Gi-protein in cortical neurons , 1997, Nature.

[67]  J. Olney,et al.  Excitotoxic neurodegeneration in Alzheimer disease. New hypothesis and new therapeutic strategies. , 1997, Archives of neurology.

[68]  U. Otten,et al.  Interleukin-6 (IL-6)—A molecule with both beneficial and destructive potentials , 1997, Progress in Neurobiology.

[69]  George B. Benedek,et al.  Kinetic theory of fibrillogenesis of amyloid β-protein , 1997 .

[70]  Yizheng Wang,et al.  α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, but Not N-Methyl-D-aspartate, Activates Mitogen-activated Protein Kinase through G-protein βγ Subunits in Rat Cortical Neurons (*) , 1995, The Journal of Biological Chemistry.

[71]  S. Squazzo,et al.  Evidence that production and release of amyloid beta-protein involves the endocytic pathway. , 1994, The Journal of biological chemistry.

[72]  T. Murphy,et al.  Differential regulation of calcium/calmodulin-dependent protein kinase II and p42 MAP kinase activity by synaptic transmission , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[73]  F. Holsboer,et al.  Cellular Localization of Interleukin 6 mRNA and Interleukin 6 Receptor mRNA in Rat Brain , 1993, The European journal of neuroscience.

[74]  L. Trussell,et al.  Desensitization of AMPA receptors upon multiquantal neurotransmitter release , 1993, Neuron.

[75]  K. A. Yamada,et al.  Diazoxide blocks glutamate desensitization and prolongs excitatory postsynaptic currents in rat hippocampal neurons. , 1992, The Journal of physiology.

[76]  J. Hardy,et al.  Alzheimer's disease: the amyloid cascade hypothesis. , 1992, Science.

[77]  T. Hirano,et al.  Structure and expression of human B cell stimulatory factor‐2 (BSF‐2/IL‐6) gene. , 1987, The EMBO journal.

[78]  Denise C. Park,et al.  Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging and the Alzheimer's Association workgroup , 2011 .

[79]  W. Klein,et al.  Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. , 2007, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[80]  E. Mackenzie,et al.  NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production. , 2005, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[81]  David M Holtzman,et al.  Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo. , 2005, Neuron.

[82]  D. Kirschner,et al.  Kinetic theory of fibrillogenesis of amyloid beta-protein. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[83]  L. Kaczmarek,et al.  Glutamate receptor-driven gene expression in learning. , 1993, Acta neurobiologiae experimentalis.

[84]  A. Yu,et al.  Astrocytic response to injury. , 1992, Progress in brain research.

[85]  R. C. Collins,et al.  Excitotoxic mechanisms of epileptic brain damage. , 1986, Advances in neurology.