AMPA-ergic regulation of amyloid-β levels in an Alzheimer’s disease mouse model
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[1] Y. Sheline,et al. Redundant Gs-coupled serotonin receptors regulate amyloid-β metabolism in vivo , 2016, Molecular Neurodegeneration.
[2] F. C. Bennett,et al. New tools for studying microglia in the mouse and human CNS , 2016, Proceedings of the National Academy of Sciences.
[3] D. Gruol,et al. IL-6 regulation of synaptic function in the CNS , 2015, Neuropharmacology.
[4] Thomas Wisniewski,et al. Clearance systems in the brain—implications for Alzheimer disease , 2015, Nature Reviews Neurology.
[5] D. Holtzman,et al. Three dimensions of the amyloid hypothesis: time, space and 'wingmen' , 2015, Nature Neuroscience.
[6] L. Tan,et al. Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease. , 2015, Annals of translational medicine.
[7] S. Sensi,et al. Age-Dependent Modifications of AMPA Receptor Subunit Expression Levels and Related Cognitive Effects in 3xTg-AD Mice , 2014, Front. Aging Neurosci..
[8] S. Cregan,et al. Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease , 2014, Molecular Brain.
[9] Robert J. Williams,et al. AMPA Receptor Activation Promotes Non-Amyloidogenic Amyloid Precursor Protein Processing and Suppresses Neuronal Amyloid-β Production , 2013, PloS one.
[10] A. Quintana,et al. Interleukin-6, a Major Cytokine in the Central Nervous System , 2012, International journal of biological sciences.
[11] David G. Jones,et al. Cortical development of AMPA receptor trafficking proteins , 2012, Front. Mol. Neurosci..
[12] A. Fisher. Cholinergic modulation of amyloid precursor protein processing with emphasis on M1 muscarinic receptor: perspectives and challenges in treatment of Alzheimer’s disease , 2012, Journal of neurochemistry.
[13] M. Mintun,et al. Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans , 2011, Proceedings of the National Academy of Sciences.
[14] D. Holtzman,et al. Opposing Synaptic Regulation of Amyloid-β Metabolism by NMDA Receptors In Vivo , 2011, The Journal of Neuroscience.
[15] Denise C. Park,et al. Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.
[16] J. Morris,et al. Alzheimer’s Disease: The Challenge of the Second Century , 2011, Science Translational Medicine.
[17] Y. Sara,et al. Use-Dependent AMPA Receptor Block Reveals Segregation of Spontaneous and Evoked Glutamatergic Neurotransmission , 2011, The Journal of Neuroscience.
[18] Jee Hoon Roh,et al. Neuronal activity regulates the regional vulnerability to amyloid-β deposition , 2011, Nature Neuroscience.
[19] J. Morris,et al. Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease , 2010, Science.
[20] E. Capetillo-Zarate,et al. Effects of Synaptic Modulation on β-Amyloid, Synaptophysin, and Memory Performance in Alzheimer's Disease Transgenic Mice , 2010, The Journal of Neuroscience.
[21] Wenjun Gao,et al. Development of calcium‐permeable AMPA receptors and their correlation with NMDA receptors in fast‐spiking interneurons of rat prefrontal cortex , 2010, The Journal of physiology.
[22] J. Wess,et al. Deletion of M1 Muscarinic Acetylcholine Receptors Increases Amyloid Pathology In Vitro and In Vivo , 2010, The Journal of Neuroscience.
[23] P. S. St George-Hyslop,et al. Group II Metabotropic Glutamate Receptor Stimulation Triggers Production and Release of Alzheimer's Amyloid β42 from Isolated Intact Nerve Terminals , 2010, The Journal of Neuroscience.
[24] D. Dickson,et al. Massive gliosis induced by interleukin‐6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[25] Roberto Malinow,et al. Amyloid beta from axons and dendrites reduces local spine number and plasticity , 2010, Nature Neuroscience.
[26] Xiaowei Wang,et al. PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification , 2009, Nucleic Acids Res..
[27] Yan Wang,et al. Characterizing the Appearance and Growth of Amyloid Plaques in APP/PS1 Mice , 2009, The Journal of Neuroscience.
[28] Robert J. Williams,et al. Synaptic NMDA Receptor Activation Stimulates α-Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-β Production , 2009, The Journal of Neuroscience.
[29] E. Schuman,et al. Partitioning the Synaptic Landscape: Distinct Microdomains for Spontaneous and Spike-Triggered Neurotransmission , 2009, Science Signaling.
[30] Keith A. Johnson,et al. Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease , 2009, The Journal of Neuroscience.
[31] Athanasia Spandidos,et al. A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance , 2008, BMC Genomics.
[32] A. Deutch,et al. Novel Selective Allosteric Activator of the M1 Muscarinic Acetylcholine Receptor Regulates Amyloid Processing and Produces Antipsychotic-Like Activity in Rats , 2008, The Journal of Neuroscience.
[33] K. Moulder,et al. Spontaneous and Evoked Glutamate Release Activates Two Populations of NMDA Receptors with Limited Overlap , 2008, The Journal of Neuroscience.
[34] E. Marcello,et al. Amyloid flirting with synaptic failure: towards a comprehensive view of Alzheimer's disease pathogenesis. , 2008, European journal of pharmacology.
[35] Guojun Bu,et al. Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo , 2008, Neuron.
[36] R. Kauppinen,et al. Proliferating Resident Microglia after Focal Cerebral Ischaemia in Mice , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[37] H. Kettenmann,et al. Microglia: active sensor and versatile effector cells in the normal and pathologic brain , 2007, Nature Neuroscience.
[38] R. Huganir,et al. The cell biology of synaptic plasticity: AMPA receptor trafficking. , 2007, Annual review of cell and developmental biology.
[39] E. Schuman,et al. Postsynaptic Decoding of Neural Activity: eEF2 as a Biochemical Sensor Coupling Miniature Synaptic Transmission to Local Protein Synthesis , 2007, Neuron.
[40] Steven Finkbeiner,et al. NMDA and AMPA receptors: old channels, new tricks , 2007, Trends in Neurosciences.
[41] W. Klein,et al. Aβ Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease , 2007, The Journal of Neuroscience.
[42] R. Malinow,et al. AMPAR Removal Underlies Aβ-Induced Synaptic Depression and Dendritic Spine Loss , 2006, Neuron.
[43] E. Schuman,et al. Miniature Neurotransmission Stabilizes Synaptic Function via Tonic Suppression of Local Dendritic Protein Synthesis , 2006, Cell.
[44] G. Collingridge,et al. Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation , 2006, Nature Neuroscience.
[45] C. Duarte,et al. Excitotoxicity mediated by Ca2+-permeable GluR4-containing AMPA receptors involves the AP-1 transcription factor , 2006, Cell Death and Differentiation.
[46] L. Feig,et al. Age-dependent Participation of Ras-GRF Proteins in Coupling Calcium-permeable AMPA Glutamate Receptors to Ras/Erk Signaling in Cortical Neurons* , 2006, Journal of Biological Chemistry.
[47] Eric H. Chang,et al. AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[48] Steven Mennerick,et al. Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo , 2005, Neuron.
[49] E. Mackenzie,et al. NMDA Receptor Activation Inhibits α-Secretase and Promotes Neuronal Amyloid-β Production , 2005, The Journal of Neuroscience.
[50] Benjamin J. Shannon,et al. Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory , 2005, The Journal of Neuroscience.
[51] P. Seeburg,et al. The AMPA Receptor Subunits GluR-A and GluR-B Reciprocally Modulate Spinal Synaptic Plasticity and Inflammatory Pain , 2004, Neuron.
[52] R. Tanzi,et al. Clearance of Alzheimer's Aβ Peptide The Many Roads to Perdition , 2004, Neuron.
[53] D. Borchelt,et al. APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1 , 2004, Neurobiology of Aging.
[54] Nicholas R Wall,et al. Regulation of Dendritic Protein Synthesis by Miniature Synaptic Events , 2004, Science.
[55] B. Seed,et al. A PCR primer bank for quantitative gene expression analysis. , 2003, Nucleic acids research.
[56] D. Holtzman,et al. In Vivo Assessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life , 2003, The Journal of Neuroscience.
[57] P. Francis. Glutamatergic systems in Alzheimer's disease , 2003, International journal of geriatric psychiatry.
[58] M. Staufenbiel,et al. Extracellular amyloid formation and associated pathology in neural grafts , 2003, Nature Neuroscience.
[59] R. Malinow,et al. APP Processing and Synaptic Function , 2003, Neuron.
[60] M. Schwaninger,et al. Interleukin-6 (IL-6): A Possible Neuromodulator Induced by Neuronal Activity , 2002, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[61] D. Borchelt,et al. Co-expression of multiple transgenes in mouse CNS: a comparison of strategies. , 2001, Biomolecular engineering.
[62] Kortaro Tanaka,et al. Enhanced Expression of Iba1, Ionized Calcium-Binding Adapter Molecule 1, After Transient Focal Cerebral Ischemia In Rat Brain , 2001, Stroke.
[63] M. Schwaninger,et al. Induction of Interleukin-6 by Depolarization of Neurons , 2000, The Journal of Neuroscience.
[64] Robert J. Williams,et al. Ca2+-Permeable AMPA Receptors Induce Phosphorylation of cAMP Response Element-Binding Protein through a Phosphatidylinositol 3-Kinase-Dependent Stimulation of the Mitogen-Activated Protein Kinase Signaling Cascade in Neurons , 1999, The Journal of Neuroscience.
[65] Clive N Svendsen,et al. Leukocyte Infiltration, Neuronal Degeneration, and Neurite Outgrowth after Ablation of Scar-Forming, Reactive Astrocytes in Adult Transgenic Mice , 1999, Neuron.
[66] Yizheng Wang,et al. AMPA receptor-mediated regulation of a Gi-protein in cortical neurons , 1997, Nature.
[67] J. Olney,et al. Excitotoxic neurodegeneration in Alzheimer disease. New hypothesis and new therapeutic strategies. , 1997, Archives of neurology.
[68] U. Otten,et al. Interleukin-6 (IL-6)—A molecule with both beneficial and destructive potentials , 1997, Progress in Neurobiology.
[69] George B. Benedek,et al. Kinetic theory of fibrillogenesis of amyloid β-protein , 1997 .
[70] Yizheng Wang,et al. α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, but Not N-Methyl-D-aspartate, Activates Mitogen-activated Protein Kinase through G-protein βγ Subunits in Rat Cortical Neurons (*) , 1995, The Journal of Biological Chemistry.
[71] S. Squazzo,et al. Evidence that production and release of amyloid beta-protein involves the endocytic pathway. , 1994, The Journal of biological chemistry.
[72] T. Murphy,et al. Differential regulation of calcium/calmodulin-dependent protein kinase II and p42 MAP kinase activity by synaptic transmission , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[73] F. Holsboer,et al. Cellular Localization of Interleukin 6 mRNA and Interleukin 6 Receptor mRNA in Rat Brain , 1993, The European journal of neuroscience.
[74] L. Trussell,et al. Desensitization of AMPA receptors upon multiquantal neurotransmitter release , 1993, Neuron.
[75] K. A. Yamada,et al. Diazoxide blocks glutamate desensitization and prolongs excitatory postsynaptic currents in rat hippocampal neurons. , 1992, The Journal of physiology.
[76] J. Hardy,et al. Alzheimer's disease: the amyloid cascade hypothesis. , 1992, Science.
[77] T. Hirano,et al. Structure and expression of human B cell stimulatory factor‐2 (BSF‐2/IL‐6) gene. , 1987, The EMBO journal.
[78] Denise C. Park,et al. Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging and the Alzheimer's Association workgroup , 2011 .
[79] W. Klein,et al. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. , 2007, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[80] E. Mackenzie,et al. NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production. , 2005, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[81] David M Holtzman,et al. Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo. , 2005, Neuron.
[82] D. Kirschner,et al. Kinetic theory of fibrillogenesis of amyloid beta-protein. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[83] L. Kaczmarek,et al. Glutamate receptor-driven gene expression in learning. , 1993, Acta neurobiologiae experimentalis.
[84] A. Yu,et al. Astrocytic response to injury. , 1992, Progress in brain research.
[85] R. C. Collins,et al. Excitotoxic mechanisms of epileptic brain damage. , 1986, Advances in neurology.