Intracellular calprotectin (S100A8/A9) facilitates DNA damage responses and promotes apoptosis in head and neck squamous cell carcinoma.

[1]  O. Krizanova,et al.  Camptothecin, triptolide, and apoptosis inducer kit have differential effects on mitochondria in colorectal carcinoma cells , 2022, FEBS open bio.

[2]  L. Lossi,et al.  Association of Caspase 3 Activation and H2AX γ Phosphorylation in the Aging Brain: Studies on Untreated and Irradiated Mice , 2021, Biomedicines.

[3]  K. Struhl,et al.  S100A8/S100A9 cytokine acts as a transcriptional coactivator during breast cellular transformation , 2021, Science Advances.

[4]  T. Kimura,et al.  Evaluating Individual Radiosensitivity for the Prediction of Acute Toxicities of Chemoradiotherapy in Esophageal Cancer Patients , 2020, Radiation Research.

[5]  I. Koutlas,et al.  Endogenous APOBEC3B overexpression characterizes HPV-positive and HPV-negative oral epithelial dysplasias and head and neck cancers , 2020, Modern Pathology.

[6]  P. Sung,et al.  The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication , 2020, Nature Reviews Molecular Cell Biology.

[7]  L. Chow Head and Neck Cancer. , 2020, The New England journal of medicine.

[8]  I. Koutlas,et al.  Intracellular calprotectin (S100A8/A9) controls epithelial differentiation and caspase-mediated cleavage of EGFR in head and neck squamous cell carcinoma. , 2019, Oral oncology.

[9]  J. Suchánková,et al.  A role of the 53BP1 protein in genome protection: structural and functional characteristics of 53BP1-dependent DNA repair , 2019, Aging.

[10]  Ville Mustonen,et al.  The repertoire of mutational signatures in human cancer , 2018, Nature.

[11]  F. Xia,et al.  Altered DNA repair; an early pathogenic pathway in Alzheimer’s disease and obesity , 2018, Scientific Reports.

[12]  N. Jung,et al.  Secretion of the Phosphorylated Form of S100A9 from Neutrophils Is Essential for the Proinflammatory Functions of Extracellular S100A8/A9 , 2018, Front. Immunol..

[13]  M. Herzberg,et al.  Calprotectin and the Initiation and Progression of Head and Neck Cancer , 2018, Journal of dental research.

[14]  M. Santiago,et al.  Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-Dependent Protein Degradation , 2018, Journal of Virology.

[15]  H. Fan,et al.  Regulatory mechanism and functional analysis of S100A9 in acute promyelocytic leukemia cells , 2017, Frontiers of Medicine.

[16]  G. Su,et al.  Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma , 2017, Oncotarget.

[17]  H. Nishina,et al.  Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor , 2017, Journal of Virology.

[18]  A. Jemal,et al.  Cancer treatment and survivorship statistics, 2016 , 2016, CA: a cancer journal for clinicians.

[19]  S. Nuyts,et al.  HPV Positive Head and Neck Cancers: Molecular Pathogenesis and Evolving Treatment Strategies , 2016, Cancers.

[20]  R. Hasina,et al.  Involvement of calprotectin (S100A8/A9) in molecular pathways associated with HNSCC , 2016, Oncotarget.

[21]  Y. Ishii,et al.  Identification of APOBEC3B promoter elements responsible for activation by human papillomavirus type 16 E6. , 2015, Biochemical and biophysical research communications.

[22]  V. C. Vieira,et al.  Human Papillomavirus E6 Triggers Upregulation of the Antiviral and Cancer Genomic DNA Deaminase APOBEC3B , 2014, mBio.

[23]  Y. Pazhang,et al.  Calprotectin induces cell death in human prostate cancer cell (LNCaP) through survivin protein alteration , 2014, Cell biology international.

[24]  M. Santiago,et al.  APOBEC3A Functions as a Restriction Factor of Human Papillomavirus , 2014, Journal of Virology.

[25]  M. Herzberg,et al.  S100A8/A9 regulates MMP-2 expression and invasion and migration by carcinoma cells. , 2014, The international journal of biochemistry & cell biology.

[26]  B. Sorenson,et al.  S100A8/A9 (Calprotectin) Negatively Regulates G2/M Cell Cycle Progression and Growth of Squamous Cell Carcinoma , 2013, PloS one.

[27]  E. Cohen,et al.  Modifiable risk behaviors in patients with head and neck cancer , 2013, Cancer.

[28]  David J. Chen,et al.  DNA double strand break repair via non-homologous end-joining. , 2013, Translational cancer research.

[29]  N. A. Temiz,et al.  APOBEC3B is an enzymatic source of mutation in breast cancer , 2013, Nature.

[30]  J. Markowitz,et al.  Review of S100A9 biology and its role in cancer. , 2013, Biochimica et biophysica acta.

[31]  B. Sorenson,et al.  IL-1 receptor regulates S100A8/A9-dependent keratinocyte resistance to bacterial invasion , 2011, Mucosal Immunology.

[32]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[33]  C. Mathers,et al.  Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 , 2010, International journal of cancer.

[34]  R. Hasina,et al.  Dual Inhibition of Vascular Endothelial Growth Factor Receptor and Epidermal Growth Factor Receptor is an Effective Chemopreventive Strategy in the Mouse 4-NQO Model of Oral Carcinogenesis , 2010, Cancer Prevention Research.

[35]  S. Elledge,et al.  The DNA damage response: making it safe to play with knives. , 2010, Molecular cell.

[36]  Lye Mun Tho,et al.  The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer. , 2010, Advances in cancer research.

[37]  Yao Song,et al.  S100A8/A9 Induces Apoptosis and Inhibits Metastasis of CasKi Human Cervical Cancer Cells , 2010, Pathology & Oncology Research.

[38]  C. Geczy,et al.  ANTI-INFECTIVE PROTECTIVE PROPERTIES OF S100 CALGRANULINS. , 2009, Anti-inflammatory & anti-allergy agents in medicinal chemistry.

[39]  Y. Pommier,et al.  The apoptotic ring: A novel entity with phosphorylated histones H2AX and H2B, and activated DNA damage response kinases , 2009, Cell cycle.

[40]  S. Warnakulasuriya Global epidemiology of oral and oropharyngeal cancer. , 2009, Oral oncology.

[41]  M. Herzberg,et al.  Calprotectin S100A9 Calcium-binding Loops I and II Are Essential for Keratinocyte Resistance to Bacterial Invasion* , 2009, Journal of Biological Chemistry.

[42]  W. Chazin,et al.  Subversion of antimicrobial calprotectin (S100A8/S100A9 complex) in the cytoplasm of TR146 epithelial cells after invasion by Listeria monocytogenes , 2009, Mucosal Immunology.

[43]  M. Karamouzis,et al.  Head and neck cancer , 2008, The Lancet.

[44]  T. Paull,et al.  Activation and regulation of ATM kinase activity in response to DNA double-strand breaks , 2007, Oncogene.

[45]  Carole Fakhry,et al.  Case-control study of human papillomavirus and oropharyngeal cancer. , 2007, The New England journal of medicine.

[46]  I. Thorey,et al.  MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes. , 2004, Blood.

[47]  W. Chazin,et al.  Target selectivity in EF-hand calcium binding proteins. , 2004, Biochimica et biophysica acta.

[48]  S. Ghavami,et al.  Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: the role of ROS and the effect of metal ions , 2004, Journal of leukocyte biology.

[49]  A. Sancar,et al.  Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. , 2004, Annual review of biochemistry.

[50]  Boris Zhivotovsky,et al.  DNA damage-induced apoptosis , 2004, Oncogene.

[51]  S. Tickoo,et al.  Oral Cavity and Esophageal Carcinogenesis Modeled in Carcinogen-Treated Mice , 2004, Clinical Cancer Research.

[52]  M. Herzberg,et al.  Calprotectin Expression In Vitro by Oral Epithelial Cells Confers Resistance to Infection by Porphyromonas gingivalis , 2001, Infection and Immunity.

[53]  S. Nagata Apoptotic DNA fragmentation. , 2000, Experimental cell research.

[54]  D. Hanahan,et al.  The Hallmarks of Cancer , 2000, Cell.

[55]  S. Nagata,et al.  A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD , 1998, Nature.