2-(2-Iodobenzenesulfonamido)acetic acid

The title compound, C8H8INO4S, is a halogenated sulfonamide, a medicinally important class of organic compounds. In the crystal structure, intermolecular O—H⋯O hydrogen bonds involving the carboxylic acid groups form characteristic centrosymmetric dimers. These dimers are further linked through centrosymmetric dimeric N—H⋯O interactions involving the amido H atom and a sulfonyl O atom. This leads to the formation of a ribbon-like polymer structure propagating in the b direction.

[1]  Muhammad Nadeem Arshad,et al.  2-(Benzenesulfonamido)acetic acid , 2008, Acta Crystallographica Section E.

[2]  Louis J. Farrugia,et al.  WinGX suite for small-molecule single-crystal crystallography , 1999 .

[3]  Louis J. Farrugia,et al.  ORTEP-3 for Windows - a version of ORTEP-III with a Graphical User Interface (GUI) , 1997 .

[4]  Xiaohu Deng,et al.  A facile, environmentally benign sulfonamide synthesis in water , 2006 .

[5]  Anthony L. Spek,et al.  Structure validation in chemical crystallography , 2009, Acta crystallographica. Section D, Biological crystallography.

[6]  Olga Kennard,et al.  Tables of bond lengths determined by X-ray and neutron diffraction. Part 1. Bond lengths in organic compounds , 1987 .

[7]  良二 上田 J. Appl. Cryst.の発刊に際して , 1970 .

[8]  G. Sheldrick A short history of SHELX. , 2008, Acta crystallographica. Section A, Foundations of crystallography.

[9]  Muhammad Nadeem Arshad,et al.  Sodium 2-iodobenzenesulfonate monohydrate , 2008, Acta crystallographica. Section E, Structure reports online.

[10]  Muhammad Nadeem Arshad,et al.  Methyl 3-hydroxy-4-oxo-3,4-dihydro-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide monohydrate , 2008, Acta crystallographica. Section E, Structure reports online.

[11]  A. Barrett,et al.  Facile one-pot synthesis of aromatic and heteroaromatic sulfonamides. , 2003, The Journal of organic chemistry.

[12]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[13]  Muhammad Nadeem Arshad,et al.  Potassium 2-iodobenzenesulfonate monohydrate , 2008, Acta crystallographica. Section E, Structure reports online.