Multicolor imaging and the anticancer effect of a bifunctional silica nanosystem based on the complex of graphene quantum dots and hypocrellin A.

An effective theranostic platform based on porous silica nanoparticles encapsulated with the complex of a photodynamic anticancer drug and graphene quantum dots (GQDs), with the bifunction of multicolor imaging and satisfactory photo-induced anticancer activity, was successfully designed and prepared for in vitro photodynamic therapy (PDT) of superficial cancer.

[1]  Indrajit Roy,et al.  Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: a novel drug-carrier system for photodynamic therapy. , 2003, Journal of the American Chemical Society.

[2]  H. Ju,et al.  Fluorescence resonance energy transfer between quantum dots and graphene oxide for sensing biomolecules. , 2010, Analytical chemistry.

[3]  Jianrong Chen,et al.  Surface functionalization of graphene quantum dots with small organic molecules from photoluminescence modulation to bioimaging applications: an experimental and theoretical investigation , 2013 .

[4]  이화영 X , 1960, Chinese Plants Names Index 2000-2009.

[5]  Cai‐Feng Wang,et al.  Facile access to versatile fluorescent carbon dots toward light-emitting diodes. , 2012, Chemical communications.

[6]  Guangxia Shen,et al.  Light‐Triggered Theranostics Based on Photosensitizer‐Conjugated Carbon Dots for Simultaneous Enhanced‐Fluorescence Imaging and Photodynamic Therapy , 2012, Advanced materials.

[7]  Jie Xie,et al.  Novel Surfactant‐like Hypocrellin Derivatives to Achieve Simultaneous Drug Delivery in Blood Plasma and Cell Uptake , 2010, Photochemistry and photobiology.

[8]  Jing-quan Zhao,et al.  Prediction on amphiphilicity of hypocrellin derivatives , 2002 .

[9]  R. Jain,et al.  Photodynamic therapy for cancer , 2003, Nature Reviews Cancer.

[10]  Jiahong Zhou,et al.  The photodynamic property improvement of hypocrellin A by chelation with lanthanum ions. , 2003, Chemical communications.

[11]  Shumin Zhu,et al.  International Journal of Pharmaceutics , 2015 .

[12]  Xiaoling Yang,et al.  Graphene quantum dots: emergent nanolights for bioimaging, sensors, catalysis and photovoltaic devices. , 2012, Chemical communications.

[13]  Paras N Prasad,et al.  Organically modified silica nanoparticles co-encapsulating photosensitizing drug and aggregation-enhanced two-photon absorbing fluorescent dye aggregates for two-photon photodynamic therapy. , 2007, Journal of the American Chemical Society.

[14]  Z. Marković,et al.  Photodynamic antibacterial effect of graphene quantum dots. , 2014, Biomaterials.

[15]  Sheila N. Baker,et al.  Luminescent carbon nanodots: emergent nanolights. , 2010, Angewandte Chemie.

[16]  Seda Demirel Topel,et al.  Near IR excitation of heavy atom free Bodipy photosensitizers through the intermediacy of upconverting nanoparticles. , 2014, Chemical communications.

[17]  Gorjan Alagic,et al.  #p , 2019, Quantum information & computation.

[18]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[19]  Stanley B. Brown,et al.  The present and future role of photodynamic therapy in cancer treatment. , 2004, The Lancet. Oncology.

[20]  Jiahong Zhou,et al.  External heavy-atomic construction of photosensitizer nanoparticles for enhanced in vitro photodynamic therapy of cancer. , 2012, The journal of physical chemistry. B.

[21]  Jiahong Zhou,et al.  A new sol-gel silica nanovehicle preparation for photodynamic therapy in vitro. , 2010, International journal of pharmaceutics.

[22]  X. Wen,et al.  Efficient electron transfer in carbon nanodot–graphene oxide nanocomposites , 2014 .

[23]  Qiangbin Wang,et al.  Novel multifunctional NaYF4:Er3+,Yb3+/PEGDA hybrid microspheres: NIR-light-activated photopolymerization and drug delivery. , 2013, Chemical communications.

[24]  Ya‐Ping Sun,et al.  Bandgap-like strong fluorescence in functionalized carbon nanoparticles. , 2010, Angewandte Chemie.

[25]  Ross W. Boyle,et al.  Unique Diagnostic and Therapeutic Roles of Porphyrins and Phthalocyanines in Photodynamic Therapy, Imaging and Theranostics , 2012, Theranostics.

[26]  P. Choyke,et al.  New strategies for fluorescent probe design in medical diagnostic imaging. , 2010, Chemical reviews.

[27]  Y. Hsiao,et al.  Facile synthesis of highly emissive carbon dots from pyrolysis of glycerol; gram scale production of carbon dots/mSiO2 for cell imaging and drug release , 2012 .

[28]  T. Krasia‐Christoforou,et al.  Polymeric theranostics: using polymer-based systems for simultaneous imaging and therapy. , 2013, Journal of materials chemistry. B.

[29]  Liang Yan,et al.  Recent Advances in Design and Fabrication of Upconversion Nanoparticles and Their Safe Theranostic Applications , 2013, Advanced materials.

[30]  Theresa M Reineke,et al.  Theranostics: combining imaging and therapy. , 2011, Bioconjugate chemistry.

[31]  J. Aubry,et al.  Production Rate and Reactivity of Singlet Oxygen 1O2(1Δg) Directly Photoactivated at 1270 nm in Lipid Nanocapsules Dispersed in Water , 2014 .

[32]  Boris E. Burakov,et al.  Advanced Materials , 2019, Springer Proceedings in Physics.